Protein

Protein accession
I6R9Z4 [UniProt]
Representative
3CTPR
Source
UniProt (cluster: phalp2_25557)
Protein name
Putative N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKIVIHCSDTPNGRDDTAEDIHGWHLAKGWDGIGYHHVIEVGGAVRAGRPHYWIGSHVAGYNEDSLGICMIGRDQFDGDQWRALEGLVLSLNAQYPDAEVLGHRDLDSKKTCPNFDVRSWWSDVKKRSMD
Physico‐chemical
properties
protein length:131 AA
molecular weight:14757,3 Da
isoelectric point:5,85
hydropathy:-0,59
Representative Protein Details
Accession
3CTPR
Protein name
3CTPR
Sequence length
233 AA
Molecular weight
25259,72800 Da
Isoelectric point
8,76378
Sequence
MRPVNTIVIHCSATPEGRPVSVETIRRWHLDRGWRDIGYHYVIDLDGNVHEGRPIGQIGAHVRGHNTGTIGICYVGGVTNDGRLAPKDTRTPAQVEALRSLVAELAETYPGIMTVKGHRDFPRVAKACPCFDAQPELQPVVAAVRAGRLAPRSRPEPADPIEPAFPPDPEPNAGKSLLQSKTNLSAIGAFVTSVVTALTSLETWVAALVIVIAAGFAFWIIRERMQKARELGV
Other Proteins in cluster: phalp2_25557
Total (incl. this protein): 25 Avg length: 219,4 Avg pI: 8,49
Protein ID Length (AA) pI
3CTPR 233 8,76378
1IJTf 273 8,92637
1P5oe 186 9,63288
1jZZJ 273 9,32775
32Z5E 172 9,74931
4PqZ9 250 8,37594
4UreV 246 9,71334
4Utt9 246 9,65983
4Uux6 269 9,47036
7FTuq 214 9,29784
7RcyP 313 9,87477
7hfDp 233 9,74583
7uayE 225 7,87225
7wg23 230 8,86745
81nC7 308 9,64320
8dxZg 269 9,86477
8qgG7 247 9,79792
A0A411BKB7 145 5,89178
A0A6B7KSC9 163 6,51678
A0A6C6Y1I7 163 6,65803
A0A6H0X8J6 145 5,95203
A0A7T7CLE0 163 6,65803
A0A899IPJ1 134 6,53526
A0AB38ZLK5 253 9,61070
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36193
72BPm
 409 59,2% 140 5.775E-61
2 phalp2_3887
6RreM
 7260 57,8% 140 5.229E-57
3 phalp2_9794
8qYns
 5 38,9% 231 2.791E-54
4 phalp2_35819
4CbZx
 312 38,6% 238 8.769E-50
5 phalp2_28171
8yYQh
 287 38,8% 234 1.323E-47
6 phalp2_3620
4OVfK
 7 32,0% 303 2.673E-42
7 phalp2_11611
1k5JO
 2203 45,0% 153 4.997E-42
8 phalp2_12934
2XGYf
 62 41,7% 151 2.899E-32
9 phalp2_14660
5KVev
 6 38,6% 145 1.877E-31
10 phalp2_1028
6VxJI
 1 37,7% 175 3.085E-30

Domains

Domains [InterPro]
Ami2
Disordered region
Representative sequence (used for alignment): 3CTPR (233 AA)
Member sequence: I6R9Z4 (131 AA)
1 233 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Marinomonas phage P12026
[NCBI] 		1176423 No lineage information
Host Marinomonas
[NCBI] 		28253 Proteobacteria > Gammaproteobacteria > Oceanospirillales > Oceanospirillaceae >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
JQ867100 [NCBI]
CDS location
range 16388 -> 16783
strand +
CDS
ATGAAAAAAATAGTGATCCATTGCAGCGACACACCGAACGGGCGCGATGACACGGCCGAGGATATTCACGGCTGGCACTTGGCGAAGGGCTGGGATGGCATCGGGTATCATCATGTTATCGAAGTGGGGGGGGCGGTCAGGGCAGGCCGCCCTCATTACTGGATTGGTTCACACGTCGCGGGCTATAACGAGGATTCGTTAGGTATCTGCATGATTGGCCGAGATCAGTTCGATGGCGACCAGTGGCGAGCATTAGAGGGATTGGTCTTATCTCTTAATGCGCAATACCCAGATGCCGAGGTGTTGGGGCATCGCGACTTAGACAGCAAAAAGACGTGCCCAAACTTTGATGTTAGGTCCTGGTGGTCTGACGTAAAAAAGCGGAGTATGGATTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0002688f41_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3CTPR) rather than this protein.
PDB ID
3CTPR
Method AlphaFoldv2
Resolution 85.81
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50