Protein

Protein accession
E5EPF0 [UniProt]
Representative
7BEyZ
Source
UniProt (cluster: phalp2_29178)
Protein name
Putative N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTTFTITAGHGAGDPGALGFGRREADIAVDMRNMVTFYLERDGFKVINDGDGKENKSLTEAIKLINKSDIAVEFHCNASANATAQGVETLAKTQHAKLAKDISQAITGVTGWKLRREDGWYKDANEHSRLGFVRNGGLIVELFFITNAAELKIWDEKKWLIAKAVAAVLAKA
Physico‐chemical
properties
protein length:172 AA
molecular weight:18766,2 Da
isoelectric point:7,85
hydropathy:-0,20
Representative Protein Details
Accession
7BEyZ
Protein name
7BEyZ
Sequence length
259 AA
Molecular weight
28146,92450 Da
Isoelectric point
9,49221
Sequence
MKLIENWKESYKLLTVKIGALLSAFFTLLILFSDHLVTVWNQIPQAWKDQIPETWGFWIGGIVSVAMILARLKSQPKLQQQPLGFVTVTAGHSNFDPGAVNGKYKEAELVTNFRNAVNFYLNQAGIKTRTDGIGSKNEPLSSAVKLIKGSSVAVEFHLNAAGSSQANGIETIALPADKLLAQKLSNAVASALGSRVRGQNGWIDQSDSARGKLAFVNGGGLILELGFISNQDELARFNARYWLAARAVANVLIEHEKGN
Other Proteins in cluster: phalp2_29178
Total (incl. this protein): 91 Avg length: 244,9 Avg pI: 9,10
Protein ID Length (AA) pI
7BEyZ 259 9,49221
1L92H 237 9,00193
1a4ha 249 9,17554
1afxJ 248 9,46514
1b040 249 9,49737
1b0e3 250 9,17677
1bEHN 262 9,39712
1bF2b 249 8,92296
1bMnk 246 9,31853
1bPPF 249 9,28134
1bScu 249 9,22132
1bVNe 253 9,20991
1bVvW 248 9,17664
1bWrG 248 9,14292
1c2EE 248 9,45411
1c3xx 253 9,08342
1c7yS 248 9,04151
1caUE 248 9,00122
1cbBe 258 9,08000
1cbFO 250 8,99368
1cbHX 249 9,54211
1cd1X 248 9,32131
1cenm 248 8,67069
1cequ 258 9,45488
1cgIX 248 9,09644
1chaH 248 9,00193
1chdj 249 8,85269
1cihD 250 9,20410
1cj9L 249 9,62966
1cmDL 250 9,17683
1coO0 248 9,14299
1cpct 253 9,20849
1cpqG 247 9,34497
1cpvx 262 9,39712
1gyTv 248 9,34471
1gyzu 248 9,11694
1jPPJ 250 9,17677
1jSfU 261 9,34529
1kk6J 249 8,98027
1mLcz 248 9,07762
1msoB 250 9,38552
1mt6P 262 9,43438
1peOi 250 9,26393
3MDYm 250 9,17677
3MMvU 208 9,34574
3MW8e 258 9,47558
4TY64 249 9,52084
4fvLw 257 9,20378
4pSkg 213 9,19875
4z8vi 248 9,29952
5HUEn 258 9,48203
73JBj 248 9,17541
73JC7 249 9,44154
73Jyd 258 9,13506
75Vjy 249 8,68829
76SGO 247 9,44096
76SXt 250 9,39641
77eQj 248 9,15962
7UGTq 263 9,20385
7UGxb 257 9,09767
7UHjo 257 9,22125
7Vj86 250 8,68958
7XQZ7 262 9,07942
7YgQZ 258 9,36727
7d3bj 260 9,31815
7hpvd 257 8,97879
7mCqR 256 9,43935
7mCuC 248 8,93901
7oaYV 246 9,20417
7oaZS 258 9,13519
7ovEc 249 9,51980
7r38s 227 9,34555
7vBdq 263 9,31795
7vBfY 255 9,23150
7vQRD 252 9,14337
7vR05 266 9,15524
7xrEz 249 9,15478
7yC7C 225 9,04641
7yC9l 250 9,14324
8jMw7 258 9,39667
8oVpC 259 9,31776
8q0rO 259 9,22151
CH8t 249 9,44154
eQyb 223 9,43471
U5PZX6 177 9,04725
A0A1J0GUZ6 193 6,75272
A0A2P9HY81 209 5,33027
A0A9E7E141 173 8,78783
A0A9E7E1A7 173 8,78783
A0A9E7E1N5 173 6,90977
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37678
3Xhrk
 501 51,4% 171 7.096E-74
2 phalp2_23090
4q8sF
 5 45,1% 175 2.151E-51
3 phalp2_3696
51zXL
 234 34,8% 178 8.246E-29
4 phalp2_32223
7cpfr
 3 32,7% 180 6.195E-27
5 phalp2_14862
15a1
 46 32,2% 177 1.561E-26
6 phalp2_29815
2324Y
 17 25,2% 182 3.208E-19
7 phalp2_24413
4m1OU
 1246 26,7% 176 1.984E-18
8 phalp2_6374
7yZe6
 41 29,6% 172 1.528E-15
9 phalp2_27233
3PKbz
 18 25,4% 177 1.688E-14
10 phalp2_8747
8qMi4
 13 31,5% 184 4.526E-13

Domains

Domains [InterPro]
Unannotated
Ami3
Representative sequence (used for alignment): 7BEyZ (259 AA)
Member sequence: E5EPF0 (172 AA)
1 259 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Acinetobacter phage Acj9
[NCBI] 		760939 Straboviridae > Acajnonavirus > Acajnonavirus acj9
Host Acinetobacter johnsonii
[NCBI] 		40214 Proteobacteria > Gammaproteobacteria > Pseudomonadales > Moraxellaceae > Acinetobacter >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM004124 [NCBI]
CDS location
range 10258 -> 10776
strand -
CDS
ATGACAACTTTCACAATTACTGCAGGCCATGGTGCCGGAGATCCAGGTGCCTTAGGATTTGGACGACGCGAAGCAGATATCGCAGTTGATATGCGCAATATGGTCACGTTCTATCTTGAACGTGACGGCTTCAAGGTTATCAATGATGGGGATGGCAAAGAAAACAAATCTTTGACCGAAGCTATCAAATTGATCAATAAGTCTGATATTGCTGTTGAGTTTCATTGCAATGCTAGTGCAAATGCCACCGCTCAAGGTGTCGAAACACTCGCAAAAACACAGCATGCTAAACTTGCAAAAGACATCTCTCAAGCTATTACAGGCGTTACTGGCTGGAAACTTCGACGCGAAGATGGATGGTACAAGGATGCTAATGAGCATAGTCGCCTAGGTTTTGTACGTAATGGTGGCCTCATTGTTGAATTGTTCTTCATCACCAATGCAGCAGAACTCAAGATTTGGGATGAGAAGAAATGGCTCATTGCAAAGGCTGTTGCAGCGGTTCTAGCAAAGGCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001ebcc4a_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7BEyZ) rather than this protein.
PDB ID
7BEyZ
Method AlphaFoldv2
Resolution 89.93
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50