Protein

Protein accession
B6D7J9 [UniProt]
Representative
7804q
Source
UniProt (cluster: phalp2_29128)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVLVLDISKWQPTVNYSGLKEDVGFVVIRSSNGTQKYDERLEQHAKGLDKVGMPFGLYHYALFEGGQDTINEANMLVSAYKKCRQLGAEPTFLFLDYEEVKLKSGNVVNECQRFIDHVKGQTGVKVGLYAGDSFWKTHDLDKVKHDLRWVARYGVDNGKPSTKPSIPYDLWQYTSKGRIKAIASPVDMNTCSSDILNKLKGSKAPVKPAPKPTPSKPAPAKPAPKTTTKYVNTAHLNIREKASADSKVLGVLDLNDSVQVISESGGWSKLKSGNKQVYVSSKYLSKSKTTPKAKPSSKQYYTIKSGDNLSYIAKKYKTTVKQIQNWNGIKDANKIYAGQKIRVK
Physico‐chemical
properties
protein length:344 AA
molecular weight:38260,4 Da
isoelectric point:9,69
hydropathy:-0,60
Representative Protein Details
Accession
7804q
Protein name
7804q
Sequence length
303 AA
Molecular weight
33655,18390 Da
Isoelectric point
9,53979
Sequence
MGKLVDISKYQANVNYQKLKSEVDYVILRSSYGTQKFDELLDTHLKGVIGAGIPFGLYHYALMEGGQDTINEADMLIKAVKKAKKLGKVPSYLFVDVEEKHCVDIISETNRFIIEVQNKTGIKCGLYSGDAFVKQHNLLKVNTPIRWTARYGQNDGKVNMKYQPTTPFHIWQYTSAGKLSSISGNLDLNTCSTAVLNQLRGSSAPTPTPKPKPATTKKPDRQYAEKGVFTATTTVAIKYTPKVSTAQVAKLTPNESVHYRRVAFSDGYVWVQYMRSIGKLAWACAGKASADNSKNAEKYGTFK
Other Proteins in cluster: phalp2_29128
Total (incl. this protein): 3 Avg length: 330,3 Avg pI: 9,64
Protein ID Length (AA) pI
7804q 303 9,53979
8KVCs 344 9,69290
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32227
7cHL2
 31 34,9% 229 3.129E-37
2 phalp2_32637
21xEV
 86 36,0% 211 3.789E-32
3 phalp2_354
72wcG
 31 32,5% 227 4.414E-31
4 phalp2_10110
c1k0
 16 32,1% 230 2.649E-26
5 phalp2_12693
24JaA
 16 34,2% 190 6.599E-26
6 phalp2_24235
2VKgf
 225 27,5% 279 1.212E-25
7 phalp2_2120
3gPQA
 3 32,9% 191 8.486E-24
8 phalp2_19565
3TIJJ
 398 27,3% 223 7.055E-23
9 phalp2_5615
4g2xP
 40 29,7% 202 2.362E-22
10 phalp2_29740
1rkWk
 100 30,3% 234 4.319E-22

Domains

Domains [InterPro]
GH25
SH3_5
Representative sequence (used for alignment): 7804q (303 AA)
Member sequence: B6D7J9 (344 AA)
1 303 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF08460

Taxonomy

  Name Taxonomy ID Lineage
Phage Listeria phage P40
[NCBI] 		560178 No lineage information
Host Listeria
[NCBI] 		1637 Firmicutes > Bacilli > Bacillales > Listeriaceae >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
EU855793 [NCBI]
CDS location
range 18076 -> 19110
strand +
CDS
ATGGTATTAGTTTTAGACATTTCAAAATGGCAACCGACAGTGAATTATTCAGGACTAAAAGAAGATGTAGGATTCGTTGTCATTCGTTCTAGCAACGGAACACAGAAGTATGATGAGAGATTAGAGCAACACGCAAAAGGCTTAGATAAAGTGGGAATGCCTTTCGGACTGTACCACTACGCTTTATTTGAAGGTGGACAAGATACTATCAATGAAGCGAATATGTTAGTTAGCGCATATAAGAAATGTCGTCAATTAGGCGCAGAACCAACATTCTTGTTCTTAGATTATGAAGAAGTCAAGTTAAAATCTGGTAATGTGGTAAACGAATGTCAGAGATTTATAGACCATGTGAAAGGTCAAACTGGGGTCAAAGTAGGACTTTATGCTGGGGATAGTTTTTGGAAGACGCACGATTTAGATAAAGTCAAGCACGATTTAAGATGGGTAGCTAGATATGGGGTAGATAACGGTAAACCGTCTACAAAACCATCTATACCTTATGATTTGTGGCAGTATACTTCCAAGGGGCGAATTAAAGCCATTGCTTCACCTGTAGATATGAATACATGTTCTAGCGACATATTGAACAAATTAAAAGGTTCAAAAGCACCTGTTAAACCAGCACCAAAACCGACACCTAGTAAGCCAGCACCAGCGAAACCAGCACCAAAAACGACTACTAAATATGTCAATACGGCACATTTAAATATTCGTGAAAAGGCAAGTGCTGACTCGAAAGTATTGGGAGTTCTTGACCTCAACGATTCCGTACAGGTCATTTCTGAATCAGGTGGATGGTCTAAGTTGAAATCTGGGAACAAGCAAGTATATGTTTCTAGCAAGTATCTTAGTAAGTCAAAAACGACACCGAAGGCGAAACCAAGCTCGAAACAGTATTATACTATTAAAAGCGGTGATAATTTAAGTTACATTGCTAAGAAGTATAAAACTACAGTAAAACAGATTCAAAACTGGAACGGTATCAAGGATGCTAACAAAATTTACGCAGGTCAAAAAATTAGAGTTAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
4JZ5
Method PDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
B6D7J9
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00018198e0_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7804q) rather than this protein.
PDB ID
7804q
Method AlphaFoldv2
Resolution 92.54
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50