Protein

Protein accession
D6PSS2 [UniProt]
Representative
5tR7x
Source
UniProt (cluster: phalp2_18353)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPHYDVVDTSNNNGIMTVANWRSMKKYGVKAMIAKLSEGTYFTDQTAKQSIRNAVSAGLHVNGYHFSRFTTVAGAKAEAQMAARSALKAGLGKSSVIVLDFEATNSGWNQNSKIVKAWINEVHRMGYPKTDVYTMGSWINSVPLNNSGRGGWVANYPYNPSGFKLYTGYNGWQWTSSMHFPGCYGTFDVSQMYSNYYYGTATKAVKPKKAIYYRYNPKMIYARTPINRYKDVAFKHKVDSFPAGTVFAIAKVVTYGKITRFQLANGYYITSNQDNVNRLYYVAGGDVKRVKSVRGTHRYKDKALKHVVDWQPAGTEFDVAKIV
Physico‐chemical
properties
protein length:323 AA
molecular weight:36293,8 Da
isoelectric point:9,84
hydropathy:-0,43
Representative Protein Details
Accession
5tR7x
Protein name
5tR7x
Sequence length
411 AA
Molecular weight
45782,00890 Da
Isoelectric point
9,32833
Sequence
LRFKKIILGAAIIVAPFLWSQKANAAMTQNSTQPRTDMVDVSSNNGYVSVSDYQQMRAQGVKSVVVKATEGTTYKNPYAKEQAQNADKAGLSINFYHFSHFTSVSDAQAEANYFADYVQTITSDRHVVMVNDEESITSTWYTFAQNNLFNSAFTKQLNQRGYYSTDIYSSASWFNYRFSADNANKGWVAAYPSVPTGTRYSTNNNWQWGSDFQFWNMLGRNFDVSQNYNDKYYHVGTSNASATAQAIKNGTATATTSSLSVGDTVYIKTAANKYYGSSTSIPKFVKNKNYHVLSVSGNRVVIREILSAVNRTDVVKVNTSTSTSTGSSALPSGVHAQNGTFTPNQRLMVWHGAGVSPTYQYYYSGESIKYVGYIDNWSAGYRYVVYKGASGNWCYVADRHLSPNYMLGYAR
Other Proteins in cluster: phalp2_18353
Total (incl. this protein): 6 Avg length: 387,8 Avg pI: 9,33
Protein ID Length (AA) pI
5tR7x 411 9,32833
5oNF0 419 9,23473
7g5i7 414 8,56754
7iNqs 410 9,15021
A0A4Y5FE66 350 9,88205
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17635
6JmE3
 482 35,2% 289 2.911E-49

Domains

Domains [InterPro]
Disordered region
GH25
Unannotated
Unannotated
Representative sequence (used for alignment): 5tR7x (411 AA)
Member sequence: D6PSS2 (323 AA)
1 411 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage LBR48
[NCBI] 		755164 Anamdongvirus > Anamdongvirus LBR48
Host Lactobacillus brevis
[NCBI] 		1580 Firmicutes > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
GU967410 [NCBI]
CDS location
range 3940 -> 4911
strand +
CDS
ATGCCGCATTATGATGTTGTGGATACGTCCAATAACAATGGAATCATGACCGTTGCCAATTGGCGTTCAATGAAAAAGTATGGTGTCAAAGCCATGATAGCTAAACTATCCGAAGGCACGTACTTCACTGACCAAACGGCCAAGCAAAGCATTCGTAACGCGGTATCTGCTGGCTTACACGTCAACGGCTATCACTTTTCCCGATTTACGACAGTGGCTGGGGCTAAGGCCGAAGCCCAGATGGCAGCCCGAAGTGCGCTTAAGGCAGGATTGGGCAAGAGCAGTGTGATCGTACTTGACTTTGAAGCCACCAACTCTGGTTGGAATCAGAACTCTAAAATTGTTAAGGCCTGGATTAACGAAGTTCATCGCATGGGCTATCCCAAAACGGATGTCTATACGATGGGTAGCTGGATTAATTCAGTGCCATTGAACAACTCGGGCCGTGGTGGTTGGGTAGCTAACTACCCTTATAACCCGTCAGGATTTAAGCTCTATACCGGATATAATGGTTGGCAATGGACATCAAGCATGCACTTCCCGGGCTGTTATGGAACATTTGATGTGTCCCAGATGTACTCTAACTATTACTACGGCACCGCAACCAAGGCGGTTAAACCGAAGAAGGCCATCTATTACCGATACAATCCCAAGATGATCTATGCCCGGACGCCAATTAATCGCTACAAGGATGTTGCCTTCAAACACAAAGTAGACAGTTTCCCGGCCGGCACCGTATTTGCGATTGCTAAAGTGGTAACCTATGGTAAAATTACCCGGTTCCAGTTGGCCAACGGGTACTATATCACGTCTAACCAAGACAATGTAAATCGACTTTACTATGTGGCTGGTGGTGATGTCAAACGAGTGAAGTCTGTACGCGGTACTCATCGGTACAAAGATAAGGCCCTCAAACATGTTGTGGACTGGCAGCCAGCCGGCACTGAATTTGATGTCGCTAAGATCGTCTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi0001d1c4af_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (5tR7x) rather than this protein.
PDB ID
5tR7x
Method AlphaFoldv2
Resolution 80.36
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50