Protein

Protein accession
Q38317 [UniProt]
Representative
78KBx
Source
UniProt (cluster: phalp2_2696)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTQTIENRAYGVDVSSFNNANVTEYTNAGANFVLVKVSEGLDYRNPKAKAQVDSTKQNNVVPMGYHYAHFGADSNRAVQEGNYAISSAKLAGVVVGSFLACDYEQGSGNETRGDREANTTAILAFLDTIVSAGYKPLLYSGAYLMKNKINTSRILAKYPDCLWVAAYPLGNGVSANVPNFEYFPSMDGVAIWQFTDNWKGMNVDSNIAVKSLSFNFNVAKPASQAVKTSTQPKTWTDVQGMNWYEEYGTFITGGAINLRWGATTQSSIIAQLPAGVEVKYDAWSRDQAGRVWLRQPRANGYGYLVGRVGNEAWGTFK
Physico‐chemical
properties
protein length:317 AA
molecular weight:34702,4 Da
isoelectric point:8,33
hydropathy:-0,31
Representative Protein Details
Accession
78KBx
Protein name
78KBx
Sequence length
115 AA
Molecular weight
12480,66840 Da
Isoelectric point
8,73258
Sequence
MTQTIKNRAYGVDVSSFNNANVTEYTNAGADFVLVKVSEGLDYRNPKAKTQVDSIKQNNVVPMAYHYARFSSNASVAVQEGNYAISSAKLAGVVVGSFLACDYEQGSGNETRRRS
Other Proteins in cluster: phalp2_2696
Total (incl. this protein): 3 Avg length: 189,3 Avg pI: 8,89
Protein ID Length (AA) pI
78KBx 115 8,73258
7P3zx 136 9,59775
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27605
5MaVO
 4 62,8% 70 6.275E-29
2 phalp2_36207
7gJNV
 1 45,1% 82 5.259E-20
3 phalp2_10061
7upZQ
 3 31,5% 114 1.335E-12
4 phalp2_29408
1gJlJ
 3 32,9% 79 4.343E-08
5 phalp2_3177
8tR7d
 1 29,0% 100 3.909E-07
6 phalp2_16698
CDyq
 11 31,2% 96 1.370E-06

Domains

Domains [InterPro]
GH25
Representative sequence (used for alignment): 78KBx (115 AA)
Member sequence: Q38317 (317 AA)
1 115 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage phiadh
[NCBI] 		12417 No lineage information
Host Lactobacillus gasseri
[NCBI] 		1596 Firmicutes > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
AJ131519 [NCBI]
CDS location
range 41948 -> 42901
strand +
CDS
ATGACGCAAACAATTGAAAATCGAGCTTATGGTGTTGATGTATCTAGTTTTAATAATGCAAATGTGACTGAATATACAAACGCTGGGGCTAATTTTGTTCTTGTAAAAGTATCTGAAGGCTTAGACTATCGTAACCCTAAAGCTAAAGCACAAGTAGATAGTACTAAGCAAAATAATGTGGTACCAATGGGTTACCACTATGCTCACTTTGGTGCTGATAGCAACAGAGCTGTTCAAGAAGGAAACTATGCTATTAGTTCTGCTAAGCTAGCAGGTGTGGTTGTAGGATCTTTTTTAGCTTGTGACTATGAGCAAGGAAGTGGGAACGAAACTAGAGGAGATCGTGAAGCTAATACGACGGCAATTCTAGCTTTCTTGGATACTATTGTGAGTGCTGGATATAAGCCTTTACTATATTCAGGAGCTTATTTGATGAAAAACAAAATTAATACTTCTAGAATTCTAGCCAAATATCCTGATTGTTTGTGGGTAGCAGCCTATCCACTTGGTAACGGAGTATCTGCCAATGTGCCAAATTTTGAATATTTCCCATCAATGGACGGGGTAGCAATTTGGCAATTTACTGACAATTGGAAAGGTATGAATGTGGACAGTAATATCGCCGTTAAATCTTTATCCTTTAATTTCAATGTAGCTAAACCTGCATCTCAAGCCGTTAAGACTTCCACACAGCCTAAGACATGGACGGATGTACAAGGAATGAATTGGTATGAAGAATATGGAACTTTTATCACTGGCGGAGCAATTAACCTTAGATGGGGAGCAACCACACAAAGCTCGATCATTGCACAATTACCAGCAGGTGTAGAAGTAAAGTATGATGCTTGGTCAAGAGACCAAGCAGGTCGAGTTTGGTTGAGACAACCGCGTGCAAATGGCTACGGGTATCTAGTCGGACGTGTTGGCAATGAAGCATGGGGAACATTTAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (78KBx) rather than this protein.
PDB ID
78KBx
Method AlphaFoldv2
Resolution 87.72
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50