Protein

Protein accession
A0A141HRR0 [UniProt]
Representative
8g8s
Source
UniProt (cluster: phalp2_18632)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MSINIIASNIKPIGKLTTGNRPLFIIFYDTQDRKNPDIYDIDKEDKYENSKSMFGGHYFIQKNGVIVRGREDNIYGDFSKDDNSNFNINSLGIQVEGNFDNSLINSQQKNSIITLIKHLLDKYPIRDVYTLKELNSNFKTPGLFFPINEIIDESSDKLVSKFRTIPNGNIIYTFGGRKIFYDPKNNMQGNDIIELQTLLNLLGYKCSISGIFSLETKDKLIGFQKYYNLIPDGIMDEDDYISIKKISLEYFKNDKTFNRVLYFESNPKFILFGEDIKLLQNRLNLLGYKCPISGIYDNETMDKVSEFQRNHSLTIDGKVGPITWEFITNSDYNIIRRTIEYKTPMMYGDDIKLIQNRLIELGYTDHIENIGWYDEYTKDLVMNFQKNKNIKKTGIIDNNTSKLLFK
Physico‐chemical
properties
protein length:406 AA
molecular weight:47244,3 Da
isoelectric point:6,19
hydropathy:-0,48
Representative Protein Details
Accession
8g8s
Protein name
8g8s
Sequence length
192 AA
Molecular weight
21423,64340 Da
Isoelectric point
9,48261
Sequence
VALIQGDRGLDVKILQDSLKRLGYNCIIDGDFGPKTTVAVIKFQKDHGLSIDGIVGPKTRKVLADKLAEKPLNWQSSKYFKPIEFKCKCCGILKISEELIIKLNKLREKIGKPLVINSGYRCLKYNKSISGSPKSQHLLGNAADVNIPAGWTVDSLADVGAKVGFKGIGRYYKQNFVHLDVRENYSRWTDEN
Other Proteins in cluster: phalp2_18632
Total (incl. this protein): 5 Avg length: 216,6 Avg pI: 8,06
Protein ID Length (AA) pI
8g8s 192 9,48261
5K13R 241 9,09676
A0A2I7RBW6 122 8,57992
A0A2I7RZB9 122 6,94563
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28580
851Wc
 142 41,2% 148 1.558E-43
2 phalp2_24008
45fcF
 278 39,7% 186 6.117E-35
3 phalp2_7923
ouik
 1 35,8% 212 5.322E-28
4 phalp2_34581
54ivU
 71 40,4% 136 1.659E-26
5 phalp2_18374
5Bl31
 3 38,1% 165 4.794E-17
6 phalp2_24872
5FQh
 5 34,4% 119 4.261E-14
7 phalp2_37118
1hl31
 667 34,4% 122 1.250E-12
8 phalp2_17802
8yuhy
 1 34,4% 122 7.852E-12
9 phalp2_36967
8Dlj2
 1 28,1% 142 9.039E-11

Domains

Domains [InterPro]
PG_1
PET_M15
Representative sequence (used for alignment): 8g8s (192 AA)
Member sequence: A0A141HRR0 (406 AA)
1 192 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF08291

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BpuM-BpSp
[NCBI] 		1739968 Takahashivirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KT895374 [NCBI]
CDS location
range 10056 -> 11276
strand -
CDS
TTGTCTATTAACATTATAGCTTCAAATATAAAACCAATAGGTAAATTAACTACAGGTAATAGACCTTTATTTATCATATTTTATGATACACAGGATAGAAAGAATCCTGATATTTATGATATTGATAAAGAAGACAAATATGAAAATTCTAAATCAATGTTTGGTGGTCATTATTTTATTCAAAAAAATGGTGTCATTGTAAGAGGTAGAGAAGATAATATTTATGGTGACTTCTCTAAAGATGATAATAGTAATTTTAATATTAATAGTCTAGGTATTCAGGTCGAGGGTAATTTTGATAACTCATTAATAAATAGTCAGCAAAAGAATTCAATCATTACTCTTATTAAACATTTATTAGATAAATATCCTATTAGAGACGTATATACGCTTAAAGAATTAAATTCTAATTTTAAAACTCCTGGATTATTTTTTCCCATTAATGAAATAATTGATGAAAGTTCAGATAAATTAGTAAGTAAATTTAGAACCATACCTAACGGTAATATAATTTATACTTTCGGTGGGAGAAAAATTTTCTATGATCCAAAGAATAATATGCAAGGAAATGATATAATTGAATTACAAACATTATTAAATCTATTGGGATACAAATGTTCTATATCAGGAATATTTAGTTTAGAAACAAAAGATAAACTTATTGGATTTCAAAAATATTATAATTTAATACCAGATGGAATAATGGATGAAGATGATTATATTTCTATTAAAAAAATATCTTTGGAATATTTTAAGAATGATAAAACATTTAATAGAGTTTTATATTTTGAATCTAATCCTAAATTTATTTTGTTTGGAGAAGATATTAAATTATTACAGAATAGATTAAATCTATTAGGATATAAGTGTCCTATATCAGGAATTTATGATAACGAAACTATGGATAAAGTTTCTGAATTTCAAAGAAATCATTCATTAACTATTGATGGTAAAGTTGGACCTATTACATGGGAGTTTATTACTAATAGTGATTATAATATTATACGTAGAACTATAGAATATAAGACTCCTATGATGTATGGTGATGATATAAAACTAATTCAGAATAGGTTAATAGAATTAGGTTATACTGATCATATAGAAAATATTGGTTGGTATGATGAGTATACTAAAGATTTAGTTATGAATTTTCAAAAAAATAAAAATATTAAAAAAACAGGTATAATAGATAATAATACTTCAAAGTTATTATTTAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8g8s) rather than this protein.
PDB ID
8g8s
Method AlphaFoldv2
Resolution 95.09
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50