Protein

Protein accession
A0A2D1GCZ8 [UniProt]
Representative
42vZA
Source
UniProt (cluster: phalp2_3109)
Protein name
Lysin A, protease C39 domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAAGDVVLKFDHVIIPQETYYWCGPATMQVLLSIRGIKVTEKYMADQLGTTENGTDTILYLTRELNERLGDIYRTVQVPGAGNLDQFRKHVFHSIDAGYGVGGNIMVPPANYPRPQRGERAQYGGGWIYHYWSIVGKNERLDQMAIADSGFPDYFYWVTSEQALSMISGKGYTWAANAKVADDFLGALSEADQLRVLAAAIQVGEPHRGA
Physico‐chemical
properties
protein length:210 AA
molecular weight:23283,0 Da
isoelectric point:5,50
hydropathy:-0,23
Representative Protein Details
Accession
42vZA
Protein name
42vZA
Sequence length
549 AA
Molecular weight
60894,25120 Da
Isoelectric point
4,38703
Sequence
MTDPVSVLADAMQWSVTYERYAELYPALSQSLRESECTTYDRIAMYCAQTGHESAGLYYMEEQDWNGDNYAYLEGRCDDLGNCSPGDGAKYHGRGPIQVTGKYNYTECSQWAFDEGLAPSPTFFVDIPEELAQDDNGFHGVTWYWTTQRPMNDAADAHDIYLATYYINGGYNGIEDREQRYNHCMSMGDLLLVLLQPKDERPLVGERVLSYNPDIIPQETGYWCGPASAQMCLDMRGIYESEQTLANEMGTDDGGTDYVALIEQSLDPRLPEANYSSHDAPHDPPSAPEKEALWDALKRSIDNGYGVVMNWVAPPANYPIGIKGSPNPSYGGGTVFHYVSAAGYDDNPSQRAVWIVDSGFQPWHYWISFDQCCTLIPPKAFCYANLPHTGGGEPMSDETVWVYEQLCGPINPATGYGSGWPQLGQNEHGQNLYYVDALGRTLAMLEGEPFTDIQAQPTAAPRNPLDYSALSLDQLAGPVTADGERHGWPQLGNRSVTDTQAHINSLLSEDSGEPPLQKAHQEQSSLVGNRLSSRLRERGQRQEPDSPAT
Other Proteins in cluster: phalp2_3109
Total (incl. this protein): 6 Avg length: 307,5 Avg pI: 5,09
Protein ID Length (AA) pI
42vZA 549 4,38703
6IggY 454 4,34332
A0A386KFM4 210 5,51591
A0A0K0N611 210 5,30805
A0A9E8M2V6 212 5,50670
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28047
725I0
 68 47,1% 443 5.708E-126

Domains

Domains [InterPro]
GH19
PET_C39
Unannotated
Disordered region
Representative sequence (used for alignment): 42vZA (549 AA)
Member sequence: A0A2D1GCZ8 (210 AA)
1 549 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00182, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Gordonia phage Kabluna
[NCBI] 		2041511 Zierdtviridae > Kablunavirus > Kablunavirus kabluna
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF919510 [NCBI]
CDS location
range 36789 -> 37421
strand +
CDS
ATGGCTGCTGGCGACGTCGTGCTGAAGTTCGACCATGTGATCATCCCGCAGGAGACGTATTACTGGTGCGGACCCGCGACGATGCAGGTTCTCCTGTCGATCCGGGGGATCAAGGTCACCGAGAAGTACATGGCCGACCAGCTCGGGACGACCGAGAACGGCACCGACACCATCCTCTACCTCACCCGCGAGCTGAACGAGCGCCTCGGCGACATCTATCGCACCGTGCAGGTCCCGGGAGCCGGGAACCTCGACCAGTTCCGCAAGCACGTCTTCCACTCGATCGACGCTGGGTACGGGGTCGGCGGCAACATCATGGTGCCCCCGGCCAACTACCCCCGGCCGCAGCGCGGAGAGCGCGCACAGTACGGCGGGGGATGGATCTACCACTACTGGTCCATCGTCGGGAAGAACGAGCGGCTCGACCAGATGGCGATCGCCGACAGCGGGTTCCCGGACTACTTCTACTGGGTCACCAGCGAGCAGGCGCTCTCGATGATCTCCGGCAAGGGATACACCTGGGCCGCGAACGCCAAGGTCGCCGACGACTTCCTCGGCGCACTGTCCGAAGCCGACCAGCTCCGCGTGCTCGCAGCCGCGATCCAGGTCGGCGAACCCCACCGAGGAGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000c0c1786_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (42vZA) rather than this protein.
PDB ID
42vZA
Method AlphaFoldv2
Resolution 86.78
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50