Protein

Protein accession
A0A291LGZ3 [UniProt]
Representative
7uiQL
Source
UniProt (cluster: phalp2_17750)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MATPMTAQQFVDALKKEGLTVSEKFSGWRTHERDDETGRIFGPVNGVVIHHTAGRDSLSLCYNGTSALPGPLCHTHLGKTGVATMISAGRANHAGGFTQNAHDAVVNESTSHPRPSGAEVVDGNDHYYGIEIENLGDGKDFYPQAQYDAAVKWAAAICRFHGWTAQSVIGHKEGTTRKIDPKGPVGKAGGPMWDMDQFRKDVQARLNKDVSKPATPAPAKPAPKPAPKPASKIVALKDGVRPGATHSQVSDLQRFLIKAGYGPIKGAYTDYYGPETQKAVARFHNKNPHLRTAGKSYDPAIGKSGFKELQKEAGIK
Physico‐chemical
properties
protein length:316 AA
molecular weight:33956,8 Da
isoelectric point:9,36
hydropathy:-0,61
Representative Protein Details
Accession
7uiQL
Protein name
7uiQL
Sequence length
153 AA
Molecular weight
15753,55690 Da
Isoelectric point
9,03539
Sequence
VQIAIGGDQAPSDAALRSARALYDEACAKTGRQLSKHGHRDGFATECPGGRLYAWVKAGMPAPGGGGGGGTVALDPAVKPGVNHPQVRLLQELLMKAGYGPIPGAVTDFYGANTQAAVARFHDRHPEFKSAGVSHDVAIGGRGFAVLQQEAGR
Other Proteins in cluster: phalp2_17750
Total (incl. this protein): 7 Avg length: 293,4 Avg pI: 9,34
Protein ID Length (AA) pI
7uiQL 153 9,03539
A0A2Z4QC94 317 9,55997
A0A291LHE3 317 9,35973
A0A291LHU5 317 9,34703
A0A345MI49 317 9,37249
A0A411CPT1 317 9,35954
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_40588
7Clcy
 7 33,8% 121 3.375E-05
2 phalp2_35681
3yvcZ
 6 27,4% 113 5.195E-04

Domains

Domains [InterPro]
Unannotated
PG_1
Representative sequence (used for alignment): 7uiQL (153 AA)
Member sequence: A0A291LGZ3 (316 AA)
1 153 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Amethyst
[NCBI] 		2041205 Omarvirus > Omarvirus amethyst
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF766044 [NCBI]
CDS location
range 21581 -> 22531
strand +
CDS
ATGGCTACCCCCATGACCGCCCAGCAGTTCGTTGACGCCCTCAAGAAGGAGGGCCTGACCGTCTCGGAGAAGTTCTCCGGCTGGCGCACGCACGAGCGCGACGACGAGACCGGCCGCATCTTCGGCCCCGTCAACGGCGTCGTGATCCACCACACCGCGGGTCGCGACTCGCTGAGCCTCTGCTACAACGGCACCTCCGCCCTGCCCGGCCCGCTGTGCCACACCCACCTGGGCAAGACCGGCGTCGCGACGATGATCTCGGCCGGCCGCGCCAACCACGCGGGCGGCTTCACGCAGAACGCCCACGATGCCGTGGTCAACGAGTCGACCAGCCACCCCCGCCCCTCGGGCGCTGAGGTCGTGGACGGCAACGACCACTACTACGGCATCGAGATCGAGAACCTGGGCGACGGGAAGGACTTCTACCCGCAGGCCCAGTACGACGCCGCGGTGAAGTGGGCCGCCGCGATCTGCCGCTTCCACGGCTGGACCGCTCAGTCGGTCATCGGCCACAAGGAGGGGACGACCCGCAAGATCGACCCGAAGGGTCCGGTCGGCAAGGCGGGCGGCCCGATGTGGGACATGGACCAGTTCCGCAAGGACGTCCAGGCCCGCCTGAACAAGGACGTGAGCAAGCCGGCGACCCCGGCCCCCGCGAAGCCTGCGCCCAAGCCGGCCCCGAAGCCGGCCTCGAAGATCGTGGCCCTGAAGGACGGCGTCAGGCCGGGTGCCACGCACTCCCAGGTCAGCGACCTCCAGCGGTTCCTGATCAAGGCGGGCTACGGCCCGATCAAGGGTGCGTACACCGACTACTACGGGCCGGAGACCCAGAAGGCGGTCGCCCGGTTCCACAACAAGAACCCCCACCTGCGCACGGCAGGGAAGTCGTACGACCCGGCAATCGGGAAGTCCGGCTTCAAGGAGCTCCAGAAGGAGGCAGGCATCAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A291LGZ3
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi000be4af57_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7uiQL) rather than this protein.
PDB ID
7uiQL
Method AlphaFoldv2
Resolution 89.66
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50