Protein

Protein accession
A0A2P1MY02 [UniProt]
Representative
7aJP9
Source
UniProt (cluster: phalp2_368)
Protein name
Lysin, N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAVKKTKSEAIKYLNSLAGRGWDWDGYYGWQCFDLANFYYNYVVGSGSLAGQGAKDIPFQNNFKGIATVHKNTPSFKAQAGDIVVFSGKYGQGYGHVAIVTNGNYDGNYMKFQSLDQNQIRFPLYSNI
Physico‐chemical
properties
protein length:128 AA
molecular weight:14277,8 Da
isoelectric point:9,12
hydropathy:-0,40
Representative Protein Details
Accession
7aJP9
Protein name
7aJP9
Sequence length
207 AA
Molecular weight
23082,21640 Da
Isoelectric point
5,15799
Sequence
MKIKSKLLLAIAFTSLTALNLNLHADAKDGGGSDTSKDKTPKIQNVEVEHRDYDKKSSKVQKEVAKSSTAAMNYVYSLEGKGWDFDGYYGWQCFDLVNYYWNYLYGHGLHGDYAKDIPTANNFSDEATVYKNTPSFVAQPGDVVVFNEDFGSGAGHTAIVLNGNADGNVMQFTSLDQNWYGGGADKTEVAQRITHDYETEMWFIRPN
Other Proteins in cluster: phalp2_368
Total (incl. this protein): 3 Avg length: 174,7 Avg pI: 7,96
Protein ID Length (AA) pI
7aJP9 207 5,15799
A0AAU6MXI9 189 9,60490
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13870
7vCZb
 24 56,6% 143 5.171E-55
2 phalp2_27772
7kL3N
 52 40,8% 142 2.385E-30
3 phalp2_25333
7ocj2
 56 36,0% 147 1.795E-12
4 phalp2_30026
2tAM9
 32 31,1% 135 6.060E-12
5 phalp2_568
Omza
 65 30,6% 150 6.332E-09
6 phalp2_15913
4FuWg
 22 31,9% 144 1.704E-07
7 phalp2_3543
4zM0o
 163 29,4% 136 1.017E-06
8 phalp2_17703
71dZW
 23 30,0% 130 1.961E-05
9 phalp2_24452
4BMZo
 66 27,6% 141 4.743E-05

Domains

Domains [InterPro]
Disordered region
CHAP
Representative sequence (used for alignment): 7aJP9 (207 AA)
Member sequence: A0A2P1MY02 (128 AA)
1 207 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage phiSA_BS1
[NCBI] 		2126734 Herelleviridae > Baoshanvirus > Baoshanvirus BS1
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH078572 [NCBI]
CDS location
range 142332 -> 142718
strand +
CDS
ATGGCAGTTAAGAAAACAAAGAGTGAAGCTATTAAATATCTTAATTCCTTAGCAGGTAGAGGATGGGATTGGGATGGCTATTATGGTTGGCAATGTTTTGACTTAGCAAACTTCTATTATAACTACGTAGTAGGTAGTGGAAGCTTAGCAGGACAAGGTGCAAAAGACATTCCTTTCCAAAATAATTTCAAAGGCATAGCTACAGTACACAAAAATACTCCTTCATTTAAAGCACAAGCAGGAGATATTGTGGTATTTTCTGGAAAATACGGTCAAGGTTATGGACACGTAGCTATTGTAACAAATGGAAATTATGATGGAAACTATATGAAATTCCAATCACTAGACCAGAATCAAATAAGGTTCCCTTTATATAGTAATATATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7aJP9) rather than this protein.
PDB ID
7aJP9
Method AlphaFoldv2
Resolution 77.27
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50