Protein

Protein accession
A0A1W6JQH9 [UniProt]
Representative
415Yr
Source
UniProt (cluster: phalp2_10481)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVTHPMRQGTYRVSSGYGPRWGSFHAGLDFAAPVGTPIYAAADGVVVEGRDRRNVDGFGSWIWLDCQDSVGKDFIYGHVKHSGILVKKGDRVRAGQQIGVVGNEGQSTGPHLHFEVWGHPGRLGGAHQDPARYLQGAAQPGETKPVQEARPKPKPKGGTIYGIDISEHNDGLSCARAKQEGIEFAIIRLCDGTHVDRVFHSHLADAEQAGMLVSTYWYLRAPSEGTSISQQVDVIDRQMGGRRDLPVWIDVESVDMSYPAGDPRHYLLVEKDVWDAKRELERRGYHVPGIYTGRWYWENMRGGEPSMNGLGYLWVSNYGLHNGAGDPRSLYASEGGDRHPGWDYPLGDRKPDLLQYGSRGTVAGRPNVDINAYRGTRAELEALFTGKQEELSMADIQRILDHIDRKTEETKRYVDIRITDPIGSDVKDIRQQLTGGRDKIVREDGTVDIEASYPGWKHLAVNGEGKGITPVDALALMIQILVRIERKLDQLLGGKR
Physico‐chemical
properties
protein length:496 AA
molecular weight:55048,1 Da
isoelectric point:6,42
hydropathy:-0,58
Representative Protein Details
Accession
415Yr
Protein name
415Yr
Sequence length
493 AA
Molecular weight
53519,05190 Da
Isoelectric point
7,05982
Sequence
VVYHPMKQGTYQVSSGYGSRWGTFHAGLDFAAPIGTPIYAAADGVVVQGKERYNVAGFGSWIWLDCQATVGKDFIYGHVKHDGILVKAGDRVRAGQQIGVVGNEGQSTGPHLHFETWGAPGRLGGAHQDPAKYLQGAQNPGGGAVAKPAAVAPTSAPAKGHILGVDVSYFQNGMSLKRAANEGISFAIVRTSDGTHRDWAYQSHIQDAESAGLVTAAYHYCRNPREGSTIAQQVATSVDVMGGYKRPIWLDCETAAGLSAQHVQEFKNEFERRGVRVIGIYSYIPWWEGHTIGGEPATAPFGKVWLAHYGSNPDGNPAQVYAARGGNNSRYWNYPLGNQKPVLFQYGSKAEVAGFADVDVNAFRGNKQQLKDLFYGTHTAKQVEKEEPELSDIDKKRIKLSLDQFVGYGTNKKGEPTYNGWDFNHLVKVANDKQTNGKGLTLVEMVALTMDKQNHQEEALKNLSDSFQSLIEAVSALNDTVTKLAGVNTTEDK
Other Proteins in cluster: phalp2_10481
Total (incl. this protein): 125 Avg length: 464,6 Avg pI: 5,84
Protein ID Length (AA) pI
415Yr 493 7,05982
11wdp 449 4,96911
1HJZ3 462 5,06267
1aZz0 466 5,78384
1bwMw 440 6,41481
1byiC 454 6,06315
1c5UU 483 7,71569
1cfmh 464 6,06628
1cgoL 464 5,55910
1clLW 500 5,10905
1dOVR 475 6,13210
1dPzh 466 5,56382
1e806 494 5,66107
1e8AZ 446 8,32675
1ekc7 461 5,70149
1epIW 462 4,70851
1iXjp 430 6,01001
1iXme 458 8,32501
1iXse 462 6,95973
1iY97 459 5,52761
1j0xG 461 5,53171
1j6AV 460 5,36523
1jDLs 454 8,59733
1k6tW 455 8,92263
1kqLk 497 4,88886
2bmAG 484 4,98935
3c3i9 484 5,08689
4VfDa 337 5,52477
4f3aI 468 6,67889
5RMfL 431 6,09816
5VHn7 477 5,13929
5Xs7Y 464 4,95581
60VP4 498 5,02203
61iDX 397 4,84907
62gP8 446 6,34018
6BApK 470 5,74582
6Z5RF 462 5,18044
6ZEOU 497 4,99810
6ZRtl 491 4,98679
6ayiS 466 6,13369
6e5nJ 478 5,03056
6iBtS 478 5,08251
6icLb 497 4,88050
6ifpn 437 4,91358
6jd01 414 7,89404
6mUrN 478 4,99037
6mltJ 451 4,97383
6sRp0 497 5,06529
6trGI 497 5,10206
6uenu 478 4,98446
6unIT 464 4,86214
725JR 456 8,70570
725nn 469 5,44867
74fZc 475 5,77327
75Z9m 465 6,66030
78b1L 477 5,81226
7A0lx 461 4,99094
7AeuS 447 5,66272
7BLXZ 454 9,57164
7BykU 486 6,83576
7C1nJ 431 6,40242
7MFXv 462 5,22711
7MugQ 478 4,99037
7Muna 462 5,01118
7N4OP 518 5,32243
7NaGw 449 4,99941
7OUvc 464 5,06836
7UKR5 450 4,99356
7Xulj 455 6,31250
7bbzQ 469 6,32910
7bkZz 479 5,39069
7czAJ 464 6,44466
7dIVY 453 7,81881
7gDib 447 8,72020
7gK4u 480 6,10311
7iopm 444 8,85410
7lGAs 468 5,20994
7lzLy 504 6,04650
7onjA 441 5,52483
7otwz 464 5,59758
7qPg1 470 5,41490
7qQLC 450 5,89514
7r4vH 449 6,13363
7r4zC 452 6,31404
7tMcN 438 4,96809
7ubrr 445 9,88147
7uh7Y 448 5,48408
7uhIA 501 6,29426
7ui3p 481 6,06662
7ui4q 479 6,46131
7uige 482 7,77974
7umiL 473 6,65433
7xJ0E 450 6,09271
7yfyc 442 5,87035
7zBgV 437 6,78575
7zBsS 437 6,40936
7zf2a 467 4,83685
8IKBg 496 6,42260
8IKBx 473 5,33107
8bCJ2 464 5,03249
8hQaN 460 8,72207
8hjXo 462 5,23649
BDkq 478 5,08251
BIxS 476 4,93979
BPxH 452 5,02198
HLCH 478 5,04073
HxS5 475 4,89812
KEQB 462 5,29719
KF6V 518 5,36648
Kb1O 437 4,99878
Kyjl 437 4,88954
MZl2 462 5,19289
O9HK 450 4,95400
OgPz 475 4,97412
Oi0S 475 5,03590
Ojle 484 5,02669
VMRX 462 5,24626
VOCd 464 4,94251
oFNZ 462 5,01118
oSqc 450 4,79780
wIsF 455 4,95638
x1E3 449 4,99941
ytP2 497 5,00725
zgD9 491 4,98679
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2750
7y5mT
 4 59,4% 355 1.154E-139
2 phalp2_36852
7d3iJ
 93 33,3% 390 9.264E-124
3 phalp2_8516
1nmLt
 187 23,9% 426 1.398E-32
4 phalp2_18562
757DT
 7 25,7% 423 1.196E-28

Domains

Domains [InterPro]
PET_M23
GH25
Unannotated
Representative sequence (used for alignment): 415Yr (493 AA)
Member sequence: A0A1W6JQH9 (496 AA)
1 493 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Corynebacterium phage IME1320_01
[NCBI] 		1965535 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KY653127 [NCBI]
CDS location
range 37101 -> 38591
strand +
CDS
ATGGTCACACATCCGATGAGACAAGGCACCTACAGAGTGTCTAGTGGCTACGGCCCAAGGTGGGGCAGCTTTCACGCGGGCCTAGACTTCGCGGCACCCGTCGGCACCCCAATCTATGCGGCGGCGGATGGTGTCGTTGTGGAGGGCCGAGACCGCCGAAACGTTGACGGCTTCGGGTCATGGATTTGGCTCGACTGTCAGGACAGCGTAGGCAAGGACTTCATCTACGGGCACGTGAAGCACAGCGGCATCCTCGTCAAGAAGGGCGACCGTGTGCGCGCAGGGCAACAGATAGGCGTGGTGGGCAACGAAGGGCAATCTACCGGGCCTCACCTGCACTTCGAGGTATGGGGTCATCCTGGCCGTCTTGGCGGCGCTCACCAAGACCCTGCCCGGTATTTGCAGGGCGCGGCACAGCCGGGCGAGACGAAGCCCGTACAGGAGGCCAGGCCGAAGCCGAAGCCAAAGGGAGGCACCATCTACGGCATCGACATTAGTGAGCACAACGACGGGCTAAGCTGCGCACGGGCCAAGCAGGAGGGCATCGAGTTCGCCATCATTCGCCTGTGCGATGGCACCCACGTAGATAGGGTGTTCCACTCGCACCTCGCAGACGCGGAGCAAGCCGGAATGCTCGTCTCCACCTACTGGTACCTGCGCGCCCCATCCGAGGGCACCAGCATCTCCCAGCAGGTTGATGTAATCGACCGGCAGATGGGCGGTCGCCGCGACCTGCCCGTGTGGATAGACGTGGAATCCGTCGATATGAGCTATCCCGCTGGTGACCCGCGCCACTACCTGCTCGTGGAGAAAGACGTGTGGGATGCGAAACGTGAACTGGAGCGGCGCGGCTACCACGTGCCCGGTATCTACACGGGCCGCTGGTACTGGGAGAACATGCGCGGCGGAGAACCGTCCATGAATGGCCTCGGCTATCTGTGGGTGTCCAACTACGGGCTGCACAACGGGGCGGGTGACCCGCGCAGTCTGTACGCCAGCGAGGGCGGCGACCGGCACCCCGGCTGGGACTACCCCCTAGGTGACCGCAAGCCAGACCTTTTGCAGTACGGGTCGCGGGGCACTGTCGCCGGTCGACCAAACGTGGACATCAACGCTTACCGGGGCACACGCGCCGAGCTGGAAGCACTATTCACAGGAAAACAGGAGGAGCTAAGCATGGCTGACATTCAAAGAATCCTCGACCACATCGACCGCAAAACTGAGGAGACCAAACGCTACGTCGATATTCGTATCACCGACCCTATCGGCTCGGATGTGAAGGACATTCGCCAGCAGCTGACCGGAGGCCGGGACAAGATTGTCCGCGAGGACGGCACTGTAGACATTGAGGCCTCGTACCCCGGCTGGAAGCACCTAGCGGTGAATGGGGAAGGCAAGGGGATTACCCCGGTTGACGCCCTGGCTCTTATGATCCAGATTCTTGTCCGTATTGAGCGCAAGCTCGACCAGCTCCTAGGAGGCAAGCGATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi000a27627a_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (415Yr) rather than this protein.
PDB ID
415Yr
Method AlphaFoldv2
Resolution 86.22
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50