Protein

Protein accession
B6RT63 [UniProt]
Representative
7mHjP
Source
UniProt (cluster: phalp2_18589)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYDLYTFGAGHNFKVPGASGNGYKEEVETRRVVKRLLEICYQHGIKAVDTTDNDGRTQRENLNNIVRNCNSYPKNGRLDVAIHFNQAESETGGVEVWYYDQAGLAAKVSKDVAAALGLRDRGAKEGKGLAVLNGTNAPAILIELPFLSHVGNMQAYESNFEPMCRAIVQAVTGQQVAVNGIRPVSKNVIQTGAFSPYEATDAMTALTSLKMTGVFYLQANGLPYIVTDPTSDAQLEAAKEYFKRKDWWFDVK
Physico‐chemical
properties
protein length:252 AA
molecular weight:27737,0 Da
isoelectric point:6,44
hydropathy:-0,34
Representative Protein Details
Accession
7mHjP
Protein name
7mHjP
Sequence length
332 AA
Molecular weight
37607,80720 Da
Isoelectric point
6,10351
Sequence
MYNLITVHAGHNFYVVGASANGYKEEVETRRVKNRVLELLRQVGQNCVDTTDEDGRTQQQNLANIIRNCNSHPKAGRLDIAIHFNQGASEVGGTEVWYYDQSELARKMSAEVAAAMGIRDRGPKEGKELAVLNGTNAPAILIEVAFLGHKGNMDAYERNFDKVAQAIVKVVTGKLADIGDNNPIPDVDTRQNVSLPPDWQTNNLGWLRCVERQSWVYKNPNELAEVAGKIPFGSGHVYLANAWDGKRFWFKIANDNWVPETAVLIEKDGKSKGVIWNTWNGLECYHHANYNSGIRDRVGVGQWEVELRDDNWIYIKDKGWIEFDEKVIRWIR
Other Proteins in cluster: phalp2_18589
Total (incl. this protein): 38 Avg length: 263,7 Avg pI: 6,29
Protein ID Length (AA) pI
7mHjP 332 6,10351
1c17R 261 6,00307
2YkvL 261 7,01538
2jZmQ 261 5,62077
4E5HD 255 5,88417
4E5mN 255 5,98596
4E6Hv 255 6,23117
4EmV6 261 6,23270
4EqVB 261 5,98761
4Er12 257 5,89235
72jiR 261 6,24066
742r5 263 6,38367
76mc6 259 5,88240
79nZl 261 6,94632
7BA3b 328 6,32654
7BBBK 260 6,95484
7Bzmk 255 6,94802
7Bznj 261 6,00796
7JvJd 255 6,30153
7Qygm 261 6,24219
7e3By 261 5,99824
7e3ho 261 6,01126
7e3j7 261 6,23895
7e8zD 261 6,53816
7jiir 255 6,21571
7kP4R 262 6,22668
7lurW 261 6,23986
7luva 261 5,99949
7mwJq 261 6,54185
7ov1S 261 7,67562
7ov68 256 5,90008
7ovp8 256 5,42155
7uzuA 261 5,99949
8IFcS 252 6,44159
A0A8E8U3W1 263 6,38367
A0A8E8U3V2 265 6,24566
Q5ILA1 288 7,14633
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19895
5URSo
 85 34,4% 273 2.840E-35
2 phalp2_12323
7wjSB
 3 29,5% 284 2.545E-24
3 phalp2_13106
8n51f
 2 28,9% 235 2.302E-18
4 phalp2_28871
5hUC8
 21 26,7% 209 4.594E-16
5 phalp2_29175
7A7gP
 25 23,3% 266 1.539E-08
6 phalp2_29154
7mKv1
 17 22,6% 260 2.448E-05

Domains

Domains [InterPro]
Ami3
Unannotated
Unannotated
Representative sequence (used for alignment): 7mHjP (332 AA)
Member sequence: B6RT63 (252 AA)
1 332 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Betatectivirus AP50
[NCBI] 		513550 Kalamavirales > Tectiviridae > Betatectivirus >
Host Bacillus anthracis
[NCBI] 		1392 Firmicutes > Bacilli > Bacillales > Bacillaceae > Bacillus > Bacillus cereus group

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
EU408779 [NCBI]
CDS location
range 13536 -> 14294
strand +
CDS
ATGTATGATTTATATACGTTTGGTGCTGGTCACAATTTTAAAGTACCCGGGGCAAGTGGAAACGGATATAAGGAAGAGGTAGAGACAAGACGGGTTGTAAAACGGTTGTTAGAGATATGTTACCAGCATGGTATTAAAGCTGTAGATACCACTGATAATGATGGTAGAACACAACGTGAGAATCTAAACAACATCGTTCGTAATTGTAATAGCTACCCTAAAAATGGTCGTCTTGATGTAGCTATCCATTTTAACCAAGCGGAAAGCGAAACAGGTGGTGTTGAGGTTTGGTATTACGATCAAGCTGGACTTGCTGCAAAGGTAAGTAAAGATGTGGCTGCTGCACTCGGTTTACGTGACCGTGGGGCTAAAGAGGGGAAAGGTCTTGCCGTACTGAATGGAACAAACGCCCCAGCTATATTGATAGAGTTGCCGTTTCTATCACATGTAGGGAATATGCAAGCGTATGAATCCAATTTCGAGCCTATGTGTAGAGCCATTGTACAAGCCGTGACGGGGCAACAGGTTGCGGTGAATGGGATACGTCCTGTTAGCAAGAATGTTATTCAGACGGGGGCATTCTCACCGTATGAAGCGACTGATGCAATGACGGCATTAACGTCACTAAAAATGACAGGGGTGTTCTATTTACAAGCAAATGGGTTACCATATATTGTCACAGACCCGACATCGGATGCACAGTTAGAAGCTGCAAAAGAATATTTCAAAAGAAAAGATTGGTGGTTTGATGTTAAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00018383b9_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7mHjP) rather than this protein.
PDB ID
7mHjP
Method AlphaFoldv2
Resolution 91.00
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50