Protein

Protein accession
A0A0A8WE15 [UniProt]
Representative
6ql8e
Source
UniProt (cluster: phalp2_259)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MMKVVIVPGHTLTGKGTGAVGYIDEGKENRVLTDLIVKWLKQGGAIVYTGKIDKSNNYLAEQCEIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVYAERVNKKLSTIFKNRGAKSDVRGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIVAKLIAEGILNKTIDNKENGEGKIMYKHTIVYDGAVDKIPATVVGWGYNDGKILICDIKNYIPGQTENLYVVGGGACEKIGSMTKENYTLIKGNDRFDTLYKALDFINK
Physico‐chemical
properties
protein length:269 AA
molecular weight:29907,1 Da
isoelectric point:8,99
hydropathy:-0,31
Representative Protein Details
Accession
6ql8e
Protein name
6ql8e
Sequence length
252 AA
Molecular weight
28468,29160 Da
Isoelectric point
9,00444
Sequence
MVDIIKMLTKKKCYPNKNNAKFIVIHETDNEDKGADAKRHAQALNNGNLEASVHYYVDDKVIYQTLDHKDGAWAVGKSYGTALVAGVTNYNSINIEICVNRDGNYTKARQNAIDLTRKLMKDLNISADKVIRHYDAKKKYCPRKMLDNPKLWVDFKDKIKNDGGVNSMIKYTIVYDGEVDKIPATVVGWGYNDGKILICDIKDYVPGQTQNLYVVGGGACEKIGSITKEHYTVIKGNDRFDTLYKALDFIKK
Other Proteins in cluster: phalp2_259
Total (incl. this protein): 14 Avg length: 260,4 Avg pI: 9,01
Protein ID Length (AA) pI
6ql8e 252 9,00444
74nW8 252 8,93237
74sj5 252 9,08980
74uhp 252 9,04912
74vCr 252 9,03462
7dReF 252 9,03474
7eax0 248 9,20159
7xlKt 252 8,97118
A0A0A8WI59 252 9,04912
A0A6B9J229 268 8,89266
A0A0A8WIC2 268 8,44834
E2ELK8 268 9,14750
Q331X1 309 9,28869
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24299
3nIle
 36 39,6% 174 3.294E-33
2 phalp2_7826
aMK
 29 42,5% 160 6.129E-33
3 phalp2_33479
7swgL
 97 42,2% 168 1.001E-31
4 phalp2_20292
2aQ1n
 8 41,0% 185 1.001E-31
5 phalp2_29669
8sfID
 1005 39,7% 176 4.129E-30
6 phalp2_29544
3KzTO
 225 40,2% 179 3.606E-29
7 phalp2_29527
23SbO
 38 41,4% 169 3.606E-29
8 phalp2_3987
7ylun
 65 35,5% 256 6.898E-27
9 phalp2_36615
23Gpv
 52 34,0% 191 1.300E-24
10 phalp2_37301
7Ya12
 3 29,9% 244 1.769E-24

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 6ql8e (252 AA)
Member sequence: A0A0A8WE15 (269 AA)
1 252 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage phiCD24-1
[NCBI] 		1582149 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LN681534 [NCBI]
CDS location
range 30711 -> 31520
strand +
CDS
ATGATGAAAGTAGTAATAGTACCAGGACATACACTAACAGGAAAAGGAACAGGGGCAGTTGGTTATATAGATGAAGGAAAAGAAAACAGAGTTTTAACTGATTTAATTGTTAAATGGTTGAAACAAGGTGGAGCTATTGTGTATACTGGAAAAATAGATAAATCTAATAACTATTTAGCAGAACAATGTGAAATTGCCAATAGGCAAAATGTAGATTTAGCAGTACAAATCCATTTCAACGCAAATAAAACAACTCTAAATCCTATGGGTACAGAGACAATATACAAAACTAACAATGGTAAGGTATATGCTGAAAGAGTCAACAAAAAACTATCAACAATATTTAAAAATAGAGGTGCAAAATCGGATGTAAGAGGTCTTTACTGGCTTAGTCATACAAAAGCTCCTGCAATATTAATAGAAGTGTGCTTCGTAGATAGTAAAGCAGATACAGATTATTATATTAGACATAAAGACATAGTTGCTAAATTAATAGCAGAAGGTATTTTAAATAAGACAATAGATAATAAAGAGAATGGTGAGGGAAAAATCATGTACAAACATACAATCGTTTATGATGGAGCAGTTGACAAAATACCTGCAACTGTAGTTGGCTGGGGATATAATGATGGTAAAATACTAATATGTGATATAAAAAATTACATACCAGGTCAGACAGAAAATTTATATGTTGTTGGTGGTGGAGCATGTGAGAAGATAGGTTCCATGACTAAAGAAAATTATACCCTGATAAAAGGTAATGATAGATTTGACACTCTTTACAAGGCATTAGATTTTATAAACAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0003b29455_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (6ql8e) rather than this protein.
PDB ID
6ql8e
Method AlphaFoldv2
Resolution 94.53
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50