Protein

Protein accession
Q24LG3 [UniProt]
Representative
6PwWD
Source
UniProt (cluster: phalp2_7714)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKIGVNCGHTKTGAGSGAIGKINESIETRNVGYKVIDKLKTLGNNVVDCTIDKASTQSECLSKIATQANRQDLDWFISIHFNAGKGRGCEVYTYKGKQYQDAIDVCKKISDLGFTNRGVKDGSGLYVVKKTKAKSMLIEVCFVDSEDANKYLSLGADKLATAIVEAITKHISSAEENNYNRYKHTIVYSGDDKVSADILGLYYKRKKESYLVTDIKDYKPHRTQNLYVIGGVTCNKMKEMSKTTGEKFTQLYGNDVWSTMDKAIEFVKEKL
Physico‐chemical
properties
protein length:271 AA
molecular weight:30159,1 Da
isoelectric point:9,00
hydropathy:-0,48
Representative Protein Details
Accession
6PwWD
Protein name
6PwWD
Sequence length
309 AA
Molecular weight
33991,78730 Da
Isoelectric point
5,05483
Sequence
MYVIGINDGHTIQGPGSGAVGYIIESQHTRLVGTELRALLAQRGLKVIDCTIDYASSQSEALDLIVQKANNNEMDWFISTHFNAGGGRGVEVYTYQGRQYQDALDVCESISSLGFINRGVKNGTGLYVIRKTKAKSMLVEICFTDTEDALHYLNIGYKAVAKAIADALVAHTETPAPVINYQGYVQDIGWQNSVISNSDNYAGTVGQGLRLEALVIQLENLEGNIVFEGYVQNRGWQAPRNSGESIGTIGQELRLEAVKIRLEGDNEYGIEYRTHIQDIGWTDWIANGDICGTLGESRRIEAIQIRLVK
Other Proteins in cluster: phalp2_7714
Total (incl. this protein): 2 Avg length: 290,0 Avg pI: 7,03
Protein ID Length (AA) pI
6PwWD 309 5,05483
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35186
67E6C
 93 37,3% 201 4.919E-27
2 phalp2_12323
7wjSB
 3 35,2% 196 3.902E-24
3 phalp2_14956
ooF5
 39 27,7% 313 3.529E-15
4 phalp2_15054
7qQKH
 6 30,0% 213 2.269E-11

Domains

Domains [InterPro]
Ami3
ChW
Representative sequence (used for alignment): 6PwWD (309 AA)
Member sequence: Q24LG3 (271 AA)
1 309 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF07538

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage phiCD119 (strain Clostridium difficile/United States/Govind/2006) (Bacteriophage p
[NCBI] 		2883936 Lubbockvirus > Lubbockvirus CD119
Host Peptoclostridium difficile
[NCBI] 		1496 Firmicutes > Clostridia > Clostridiales > Peptostreptococcaceae > Peptoclostridium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
AY855346 [NCBI]
CDS location
range 24719 -> 25534
strand +
CDS
ATGAAAATAGGTGTAAATTGTGGACATACAAAAACAGGAGCAGGAAGTGGAGCTATAGGTAAAATAAATGAATCAATAGAAACTAGGAATGTAGGATATAAAGTAATAGATAAATTAAAAACTCTAGGTAACAATGTAGTTGATTGTACTATAGATAAAGCATCTACACAAAGTGAGTGTTTGTCTAAAATAGCAACACAAGCAAATAGACAAGATTTAGATTGGTTTATAAGCATACATTTTAATGCAGGAAAAGGACGAGGATGCGAAGTTTACACATACAAAGGCAAACAGTATCAAGATGCTATAGACGTTTGTAAAAAAATCTCTGATTTAGGATTTACAAATCGAGGGGTAAAAGATGGAAGTGGATTATATGTAGTAAAGAAAACAAAAGCTAAAAGTATGCTAATAGAAGTATGCTTTGTGGACAGTGAAGATGCAAATAAGTATTTGAGTTTAGGAGCTGATAAATTAGCTACTGCAATAGTAGAAGCTATAACTAAACATATAAGTTCAGCAGAAGAAAACAATTATAATAGATATAAACATACTATAGTCTATTCTGGAGATGATAAAGTATCAGCAGACATTTTAGGACTATATTATAAGAGAAAAAAAGAAAGTTACTTAGTAACAGATATAAAAGACTATAAACCACATAGAACACAAAATCTATATGTAATCGGTGGAGTAACTTGTAATAAAATGAAGGAAATGAGTAAGACTACAGGAGAAAAATTTACTCAGCTATATGGTAATGATGTATGGTCAACAATGGATAAAGCTATAGAATTTGTAAAAGAAAAATTGTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
Q24LG3
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00006e1f15_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (6PwWD) rather than this protein.
PDB ID
6PwWD
Method AlphaFoldv2
Resolution 96.50
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50