Protein

Protein accession
A0A1D8EUA5 [UniProt]
Representative
7ukr9
Source
UniProt (cluster: phalp2_28100)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSYEFITSYNSPNHEGPVVPNPASLCVVHWWGAPSGQTFEGTISWLCNPASQVSAHAVATAGRVACIVDYPDRSWANGNDWANDNSITVECDPNNIDGTIDTLVEWLADMVRQNNLTADFQLKGHRDFYATECPGDYYPRLAEIRQRVADNLGGGSGQAPAPSAPAGIHVDLPSWTLPTGHFYGLVSGGEDSHGGFYEGERPAIRQIQLWLIRHGYAGAVPDSWADGIYEQPTADAVAAFQHAERPNSTDRWGEVWADDLATMAANN
Physico‐chemical
properties
protein length:267 AA
molecular weight:29030,5 Da
isoelectric point:4,51
hydropathy:-0,40
Representative Protein Details
Accession
7ukr9
Protein name
7ukr9
Sequence length
364 AA
Molecular weight
39093,31060 Da
Isoelectric point
10,13928
Sequence
MARAYTYITKFTSPNQNTRNRKIEGITIHWWGNPVGQKIEGIVSWLCDKRAGTSAHYVVSDGIVYCIVAPGKRAWHAGNSTANHTQIGIELDPNASKRTGTMRTAAALIKDLRSTYGDLPLSPHKRWTSTECPGNYDLAALDRLARGAAAPAGGASKPAVSKNAWETSPRIQGMSKAEVKRIQQMLVDANNSIGKSGVDGSYGKDTFNTVKRVQKALGLTADGVFGPATEKALAAHLKAMGKKVPARPAKPKAPAFPLPRKTGALYYYGLASGPKTSVSGQTRNTAVPGDVVQVKGRWMSKGLALFQAQLIKRGWSELKKDGPDGRFGKTTEKVVRQFQTVAGLKVDGQVGPATWAAAWETPVK
Other Proteins in cluster: phalp2_28100
Total (incl. this protein): 2 Avg length: 315,5 Avg pI: 7,32
Protein ID Length (AA) pI
7ukr9 364 10,13928
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28305
13CeQ
 161 43,7% 233 1.257E-44
2 phalp2_7198
3ejcO
 5 30,3% 329 1.716E-21
3 phalp2_30741
7uklG
 2 30,0% 369 1.716E-21
4 phalp2_36521
1qwup
 277 28,5% 329 1.589E-15
5 phalp2_26920
4uKrS
 7 25,6% 265 1.190E-12
6 phalp2_17898
EGF4
 130 27,3% 365 2.073E-11
7 phalp2_26227
ovAd
 6 25,1% 274 2.757E-11
8 phalp2_23479
6PqkT
 19 29,0% 293 8.615E-11
9 phalp2_38227
7x2xX
 21 25,2% 265 5.596E-07
10 phalp2_2829
8E642
 18 28,7% 247 9.351E-06

Domains

Domains [InterPro]
Ami2
PG_1
PG_1
Representative sequence (used for alignment): 7ukr9 (364 AA)
Member sequence: A0A1D8EUA5 (267 AA)
1 364 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Propionibacterium phage G4
[NCBI] 		1897537 Doucettevirus > Doucettevirus G4
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KX620754 [NCBI]
CDS location
range 18495 -> 19298
strand +
CDS
ATGTCTTACGAATTCATCACCAGTTATAACTCACCTAATCACGAAGGGCCGGTCGTCCCGAACCCTGCATCGCTGTGTGTGGTGCATTGGTGGGGCGCACCCTCCGGCCAGACCTTCGAAGGAACCATTTCATGGCTGTGCAACCCCGCCTCCCAGGTGTCCGCCCACGCCGTCGCCACGGCGGGCCGGGTCGCCTGCATTGTCGACTACCCGGATCGCTCCTGGGCGAACGGTAACGACTGGGCCAACGACAACTCGATCACCGTCGAGTGTGATCCCAATAACATCGACGGCACCATCGACACGCTCGTCGAGTGGCTGGCCGACATGGTGCGCCAAAACAACCTCACGGCGGACTTCCAGCTCAAGGGACACCGCGACTTCTACGCCACCGAATGCCCGGGCGATTACTACCCGCGACTCGCAGAGATCCGCCAGCGCGTCGCCGACAACCTTGGTGGGGGCAGTGGACAAGCACCTGCCCCGTCAGCCCCTGCCGGGATCCACGTCGATCTGCCGAGCTGGACCCTTCCGACAGGACACTTCTACGGCCTCGTCAGCGGCGGCGAGGACTCGCACGGCGGCTTCTACGAGGGTGAGCGACCGGCGATCCGCCAGATCCAGCTGTGGCTCATCCGCCACGGCTATGCCGGCGCGGTGCCTGACAGTTGGGCGGACGGCATCTACGAACAACCGACCGCCGACGCCGTAGCCGCTTTCCAGCACGCCGAGCGCCCCAACTCCACGGACCGGTGGGGCGAGGTCTGGGCAGACGATCTGGCCACCATGGCCGCCAACAACTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7ukr9) rather than this protein.
PDB ID
7ukr9
Method AlphaFoldv2
Resolution 88.93
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50