Protein

Protein accession
G8EYC4 [UniProt]
Representative
4lbpW
Source
UniProt (cluster: phalp2_20536)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSTLHEAAKWYKQLPHQKAAWEALEARLPKVVVDEFLAAHRADPEPVEAPQRALFTKQVFYKLTGWKPELFTDQEVADCNRLFRETGFDQDIEAARMLMANILHETANMKYMKEIANGWAYEGRKDLGNTQKGDGPRFKGAGVLQLTGRWNYSRLAKALGDPRVMEGVEYVSTTYPFMSAKTWIQENGLLNVAKTQGFDAVCRRINGGWNGYADRKAKYEICRRHIH
Physico‐chemical
properties
protein length:227 AA
molecular weight:25998,4 Da
isoelectric point:9,02
hydropathy:-0,59
Representative Protein Details
Accession
4lbpW
Protein name
4lbpW
Sequence length
237 AA
Molecular weight
26291,31520 Da
Isoelectric point
10,15301
Sequence
MSLASIRAAAEHIAREGRITAEQLAALQALDASLSEQQRREFTSLWRTPADGGEATGELVTMAQATAVFQRAPSAEQLADLNACCRRFRIRPAPRMRHFLAQVGHESGGLRWMLELADGRAYEGRRDLGNTQAGDGPRFRGAGAIQLTGRFNYQRFADFIGDKRVMEGAAYVAKRYPFTSAGFWWEQNRMNQMVDTGASVRQVSARVNGRDPANGLTDREAYYARAAAAIPWRVPVR
Other Proteins in cluster: phalp2_20536
Total (incl. this protein): 253 Avg length: 236,9 Avg pI: 6,69
Protein ID Length (AA) pI
4lbpW 237 10,15301
14hoY 243 7,54688
16oF8 242 5,72217
19Gix 224 6,82764
1A06Z 244 6,89357
1A4QK 237 5,49289
1ApeS 244 8,91664
1AqKn 244 7,56836
1E14E 225 6,22850
1GY5H 223 4,27869
1GY6p 223 4,27869
1GwNK 225 6,08441
1IiAo 249 6,53241
1N6En 260 4,70964
1S5vJ 206 4,23009
1S9pb 223 4,27869
1SASc 248 5,77850
1SIBr 249 6,70657
1UE6V 244 6,00211
1VNhN 254 5,39058
1VeNl 254 5,21273
1WU7d 243 9,00599
1fMOJ 249 4,69714
1tYeD 255 6,39151
1vVcB 226 5,58445
1zYYm 249 5,82227
21VE4 242 6,82968
22fXH 244 6,13693
22pcI 281 5,83415
28Lz0 228 5,17561
28NBX 259 4,78825
28hSi 228 5,59844
2JOTL 244 8,90774
2MnZL 226 4,71385
2N1e 244 6,89641
2PHLD 244 5,64453
2POB5 239 6,16001
2U1xz 254 5,51221
2VNIr 174 9,17354
2ZURi 224 9,09651
2cX14 224 6,42630
2gBO9 180 4,90170
2iGRW 224 6,81957
2iKLf 236 6,38503
2r4IN 247 6,17331
2s51Y 211 5,28270
2s6MU 236 5,06551
2s7LB 241 5,18300
2s82O 244 6,90062
2s956 229 5,02794
2uXpu 249 5,42411
2vBlN 249 5,62612
2vLPS 249 5,72774
30adV 226 5,94697
3219p 224 6,09532
321z6 224 6,43846
322uw 243 7,64902
32UPf 189 9,11024
34DKk 227 8,71298
36TqR 224 8,16526
37sEM 224 6,82121
3UiPs 242 8,33236
3Z78X 241 6,34462
3aSSN 245 7,00179
3aT7X 254 7,68443
3bLQO 254 6,65365
3bhMC 224 8,16526
3biQ7 224 6,10180
3mUE1 254 7,65248
3n32Z 245 6,59494
3uX17 198 4,81076
41KjS 253 5,34334
41MRQ 247 5,54586
42EPC 260 6,34871
42Pit 244 6,33348
42ZFl 238 7,06789
43hmS 245 6,14477
43kRX 253 7,76167
46J1v 197 8,79151
46SuH 228 8,94339
46aPm 224 5,75594
46hte 242 9,01418
46zAp 224 5,69370
470FV 268 7,58916
474Ki 271 8,67101
475Ah 227 6,89431
47JBV 242 7,65839
47cgm 237 6,38708
47i5M 269 8,07236
47uzs 187 5,83653
48ktM 268 8,66212
4CmQv 242 8,82316
4GxQQ 226 8,66889
4JehN 252 9,09515
4TK8l 255 5,99580
4WTdk 245 6,83883
4afag 224 8,46697
4bS5h 224 6,82161
4baE 245 7,00088
4baPj 228 9,31866
4ciEp 234 9,00696
4cihD 227 8,92966
4ciiw 223 8,51378
4cilH 227 9,54327
4cimW 234 8,87138
4ehiF 228 9,44895
4juYG 244 5,67335
4nHE5 228 9,54321
4ppuD 260 7,87057
4rJt1 243 9,01927
4rVQV 242 8,83444
4sLnY 244 8,78686
4szDL 244 5,46589
4tDDX 252 5,13929
4ttWk 244 5,68165
4v77N 226 4,67770
4x6Hu 229 4,86351
4x6xt 240 5,02078
53xBT 194 6,19149
57zkI 206 6,96814
5BSEj 243 9,01927
5HW36 230 8,68610
5Hjqf 230 8,17951
5Joa 225 6,22679
5dRd1 244 9,02830
5urVN 223 8,83773
5vHKa 242 8,64555
5wUvi 242 8,32147
5wg6V 238 8,19917
5xhkZ 238 7,66647
6BhhG 249 5,21693
6Bpr6 253 6,32228
6E2m 243 6,82451
6HKRV 289 6,22543
6JFQP 222 5,05051
6KbAG 237 7,04578
6Ly0W 268 9,20178
6NIb9 246 4,95587
6ODmq 241 4,89784
6OO9o 227 5,17464
6V1KR 222 5,13514
6V1PE 255 6,00614
6X4MT 229 4,68878
6X4if 263 5,45156
71DYT 223 6,59767
7A8l8 222 6,08731
7Cbtx 244 8,35260
7Cf9u 248 5,35102
7CtJ1 236 6,43198
7DArw 223 4,27869
7Db0q 242 5,12230
7EDgS 241 6,13176
7ETMS 243 6,45000
7EzBF 244 8,79512
7HfJH 178 4,74352
7Hsjo 240 5,33504
7IHFQ 241 5,56297
7IHes 241 5,44014
7IIgl 244 8,89885
7IJNZ 238 6,98877
7IJaU 243 8,86248
7IiQt 236 5,78515
7J2gf 244 5,29889
7WB3Y 291 8,64542
7WPTF 243 4,90915
7Wltm 256 5,42411
7YFLo 223 4,27869
7YSrT 228 4,94268
7w6XC 188 9,20088
7zM6B 252 4,84828
80dZn 225 9,29958
81lGZ 244 5,65152
82PHl 241 6,90312
82jxT 253 6,00609
82lgz 241 5,43792
831Ju 244 8,85810
83CEQ 245 6,31052
83CgU 236 6,53912
83RAA 244 6,95336
83RBS 241 5,20466
83ROw 228 5,05199
86xdZ 249 5,21693
87llF 237 7,04783
899Zv 244 6,24305
8BMzJ 249 5,98841
8C6sb 252 5,79163
8CthI 222 5,36199
8E2MP 269 8,80317
8EBNY 222 5,98818
8ECuW 223 8,24488
8HmLa 243 8,88202
8a01l 254 6,32427
8aAzZ 241 5,03391
8aS3O 241 7,61872
8aaZk 221 8,82309
8adpC 241 6,96399
8azsh 244 5,45304
8bi8z 245 5,07086
8ch4f 242 6,89573
8eCu8 252 5,02703
8ed31 243 5,09030
8fTT5 245 5,33868
8g3m5 253 5,28588
8h1VW 223 8,24488
8k6qy 224 4,74238
8kMLE 249 6,17893
8kq1L 252 5,79163
8kt3E 222 4,59773
8q16s 237 7,65498
8qiTm 249 5,98841
8tX01 176 5,19306
8tYV1 246 5,17578
8u85v 207 8,83844
8uF9f 222 4,96246
8uPOJ 213 7,59576
8uVQt 249 5,60139
8v961 248 5,81431
8yEHI 226 4,48945
8ygMQ 254 6,32427
8yzfh 234 9,64455
8zAsV 248 5,81431
ADOE 239 6,38111
AhWn 225 6,95763
CQIA 228 8,96763
Chcj 228 7,57632
FreT 268 9,35045
M72D 238 8,50249
QurW 222 4,51457
RYqN 176 5,81414
RdlH 244 5,99801
X7PZ 170 4,49803
XmrW 239 6,23458
aDYb 268 9,03249
bZg8 220 8,99091
dRS2 245 6,44312
eJfQ 228 5,03118
gD77 254 6,59221
gDhD 232 6,52400
gH2C 243 8,19853
gHyr 225 6,23708
ijN1 241 6,83838
ijXN 241 8,20697
iulk 222 6,59755
ixrW 254 7,04431
j9FA 243 8,60306
qLBt 231 5,07654
sscr 222 5,52244
tjXs 244 5,33851
uIXm 237 7,65498
vxpa 223 4,58369
x47c 234 8,63936
A0A6J5MSD1 252 9,23524
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_6162
5EIXo
 59 53,8% 180 2.552E-73
2 phalp2_10052
7rxm7
 6 54,2% 166 3.199E-69
3 phalp2_37035
K2lc
 7 42,8% 196 8.393E-60
4 phalp2_5007
1fKSs
 166 40,5% 180 2.645E-52
5 phalp2_1654
8rD3A
 4011 46,6% 150 3.537E-46
6 phalp2_22221
71It3
 12 41,0% 173 1.479E-41
7 phalp2_8404
IwNf
 80 41,7% 146 2.198E-39
8 phalp2_23269
4XEAI
 9 32,6% 208 3.004E-39
9 phalp2_33778
19xgj
 53 39,7% 176 3.251E-37
10 phalp2_14498
4ODLg
 45 36,0% 200 7.361E-36

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 4lbpW (237 AA)
Member sequence: G8EYC4 (227 AA)
1 237 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CBP42
[NCBI] 		461711 Autographiviridae > Aegirvirus > Aegirvirus SCBP42
Host Synechococcus sp. WH 7803
[NCBI] 		32051 Cyanobacteria > Oscillatoriophycideae > Chroococcales > Synechococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
JF974300 [NCBI]
CDS location
range 6325 -> 7008
strand +
CDS
ATGAGCACGCTACATGAAGCCGCTAAGTGGTATAAACAGCTTCCTCACCAGAAAGCGGCCTGGGAGGCGCTAGAAGCGCGTCTTCCCAAGGTTGTGGTGGATGAGTTCTTGGCCGCCCATAGGGCGGATCCAGAGCCCGTAGAGGCCCCTCAGAGGGCCTTATTCACCAAGCAGGTGTTCTACAAGCTGACAGGTTGGAAGCCCGAGCTATTTACAGATCAGGAAGTTGCCGACTGTAATCGCCTCTTCCGGGAGACCGGCTTCGATCAAGACATCGAGGCCGCCCGGATGCTGATGGCCAACATCCTTCATGAGACTGCCAACATGAAGTACATGAAGGAGATTGCCAATGGCTGGGCTTATGAGGGACGCAAAGATCTTGGAAACACCCAGAAAGGAGATGGCCCTCGCTTCAAGGGTGCAGGTGTACTACAGCTGACTGGAAGGTGGAACTACTCGAGGCTGGCCAAGGCCCTAGGTGATCCTAGGGTCATGGAAGGTGTTGAGTATGTATCCACCACCTATCCATTCATGTCAGCCAAGACATGGATCCAGGAGAACGGTCTCCTGAATGTTGCTAAGACTCAAGGCTTTGATGCTGTCTGTCGCCGTATCAATGGTGGATGGAATGGCTATGCCGACAGAAAAGCAAAATACGAAATCTGCCGCCGCCATATCCACTAA
CDS Source ID
[NCBI]
CDS Source
KC310805 [NCBI]
CDS location
range 19537 -> 20220
strand +
CDS
ATGAGCACGCTACATGAAGCCGCTAAGTGGTATAAACAGCTTCCTCACCAGAAAGCGGCCTGGGAGGCGCTAGAAGCGCGTCTTCCCAAGGTTGTGGTGGATGAGTTCTTGGCCGCCCATAGGGCGGATCCAGAGCCCGTAGAGGCCCCTCAGAGGGCCTTATTCACCAAGCAGGTGTTCTACAAGCTGACAGGTTGGAAGCCCGAGCTATTTACAGATCAGGAAGTTGCCGACTGTAATCGCCTCTTCCGGGAGACCGGCTTCGATCAAGACATCGAGGCCGCCCGGATGCTGATGGCCAACATCCTTCATGAGACTGCCAACATGAAGTACATGAAGGAGATTGCCAATGGCTGGGCTTATGAGGGACGCAAAGATCTTGGAAACACCCAGAAAGGAGATGGCCCTCGCTTCAAGGGTGCAGGTGTACTACAGCTGACTGGAAGGTGGAACTACTCGAGGCTGGCCAAGGCCCTAGGTGATCCTAGGGTCATGGAAGGTGTTGAGTATGTATCCACCACCTATCCATTCATGTCAGCCAAGACATGGATCCAGGAGAACGGTCTCCTGAATGTTGCTAAGACTCAAGGCTTTGATGCTGTCTGTCGCCGTATCAATGGTGGATGGAATGGCTATGCCGACAGAAAAGCAAAATACGAAATCTGCCGCCGCCATATCCACTAA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000235cc54_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (4lbpW) rather than this protein.
PDB ID
4lbpW
Method AlphaFoldv2
Resolution 89.91
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50