Protein

Protein accession
A0A291LB53 [UniProt]
Representative
3VsL8
Source
UniProt (cluster: phalp2_27241)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKDKLPAVVIAATVMGAAGLSLLNTSEGLRLKPYLDPAGIPTVCYGHTGSDIVWGKAYTKQECEFIRDRDIKSHLTGLKRCIKVPLTQNQQDAVLDLAFNIGVERTCGSTLVKKVNKRDFLGASEEFPKWNKARVNGKLVVLPGLDRRRAAERALFLKDLPEK
Physico‐chemical
properties
protein length:163 AA
molecular weight:18004,8 Da
isoelectric point:9,54
hydropathy:-0,22
Representative Protein Details
Accession
3VsL8
Protein name
3VsL8
Sequence length
265 AA
Molecular weight
28720,44240 Da
Isoelectric point
8,56877
Sequence
MADPNLTAFVKSTHARLVMFEDRMEKIKRDMQTNTVATAQNTDSIEQIRQNTQDIVDTFPALAGGLQGIAGAGKAGASYRVYRGGNCGYVGSDGRSLGILEMIPQSLKQKILAAAVGGPLVIAGVLVAHFEPGKVRGKLYIDPVGVLTVCDGHTDPDIDPKRLYTDAVCDAWRDSDLAIADRAVRRLITAPLNDWQRAAHIDFTYNLGAGNLGQSTMRRKFNAGDYAGGCAEFERWVKGRQGGVLVTLPGLVSRREVDKWVCLQS
Other Proteins in cluster: phalp2_27241
Total (incl. this protein): 2 Avg length: 214,0 Avg pI: 9,05
Protein ID Length (AA) pI
3VsL8 265 8,56877
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_15038
7cXTn
 20 47,5% 162 3.479E-35
2 phalp2_33347
6Ew8q
 73 38,1% 165 1.820E-28
3 phalp2_7028
8i7gz
 89 33,5% 164 7.272E-23

Domains

Domains [InterPro]
Unannotated
GH24
Representative sequence (used for alignment): 3VsL8 (265 AA)
Member sequence: A0A291LB53 (163 AA)
1 265 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Caulobacter phage Lullwater
[NCBI] 		2024607 Autographiviridae > Lullwatervirus > Lullwatervirus lullwater
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF621978 [NCBI]
CDS location
range 43362 -> 43853
strand +
CDS
ATGAAGGACAAGCTACCTGCTGTCGTAATTGCTGCGACTGTTATGGGTGCGGCTGGCCTATCCCTCCTGAATACCTCGGAGGGGCTTAGGCTTAAACCATATCTAGACCCCGCTGGTATCCCTACTGTATGCTACGGGCATACTGGATCAGATATCGTGTGGGGAAAGGCGTACACTAAACAAGAGTGCGAGTTTATCCGAGACCGCGACATAAAGTCGCACTTGACCGGCCTTAAGCGTTGCATTAAGGTTCCGTTAACCCAGAACCAACAAGATGCTGTTTTGGACCTTGCCTTTAACATCGGTGTTGAGCGCACTTGCGGCAGCACCCTCGTAAAGAAGGTCAACAAAAGAGACTTTCTTGGAGCCTCCGAGGAGTTCCCAAAGTGGAACAAGGCGAGGGTCAACGGAAAGCTCGTGGTTCTGCCGGGCCTGGACCGCCGTAGGGCGGCCGAAAGAGCCCTCTTCCTGAAGGACCTACCTGAGAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016020 membrane cellular component None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0020002 host cell plasma membrane cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi000be49998_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3VsL8) rather than this protein.
PDB ID
3VsL8
Method AlphaFoldv2
Resolution 75.80
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50