Protein

Protein accession
G9FHH0 [UniProt]
Representative
4Jmb8
Source
UniProt (cluster: phalp2_37839)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MGHKGKHRKQTNSNAKRFVATATGVGALGLVSAVAGTPAASAHDWSGVAHCESSGNWSINTGNGFYGGLQFTQSTWDAFKPEGAAWRADLATMADQIAAAEATLKVQGIGAWPVCGAYLGWGGVTPGVGTAPSAPSYVEPAPAPAPAASWVQPVTGTKSQGFHGGHNGVDIAAPIGTPIYAAASGSIDLAGFNNDPGGYGNYIQQTADNGAKIQYGHISEIYVSAGDYVTAGTLIAAVGNAGSSTGAHLHLRINAEDPEAYLINQGVALDWSGPSGLPVTPAPAPVSAPGEEVAVEDVPVYLAPAPEGVETVTVVPGDTLSHIAEVFGIDSWETLWDLNKDVVENPHLIYPGQVLRLA
Physico‐chemical
properties
protein length:358 AA
molecular weight:36537,1 Da
isoelectric point:4,83
hydropathy:-0,02
Representative Protein Details
Accession
4Jmb8
Protein name
4Jmb8
Sequence length
342 AA
Molecular weight
35162,30120 Da
Isoelectric point
9,96960
Sequence
MAKHHTFVGTALAGTAGAVVTLLSTSAPAQAASLTTWDKVAKCESGGNWSINTGNGYYGGLQFSASTWAAFGGRHFASRADLATKAQQITVAEKVLAVQGPGAWPVCGARAGLARGGAAPDVQTAPAKAPQAKPRMAGTSVSAKAVAYARAQLGKPYVYGATGPGSYDCSGLTMSAWKAAGVSIPRTSQAQWSGLTRVPPSAVQPGDLVVYNGAGHVALYVGDGQIIEAPRPGKSVQTAPWRSGWYATNFVGVVRPAGASVAVQNAAPEREQAAPVDRGSVRPLAPVKASGRYTVRAGDSLSAIAEARGLDGWQRLFDANRDKVRTPDLIFPGQVLRIPDAA
Other Proteins in cluster: phalp2_37839
Total (incl. this protein): 51 Avg length: 338,2 Avg pI: 8,94
Protein ID Length (AA) pI
4Jmb8 342 9,96960
11EcG 355 10,00055
16fbv 383 9,97508
1NaZR 381 9,51626
1rue7 350 11,10528
3Masw 338 9,61509
3dGMg 339 10,04064
4EBp4 308 10,12291
4Ffln 384 9,74138
4K1HQ 361 10,54208
4M8rL 364 10,64039
4N5cK 345 10,03813
4Ojjg 313 10,00719
4vafS 383 9,91493
5BA4D 322 10,30787
5BEOV 369 9,04280
5BlCv 321 10,00480
5nMVn 340 9,39976
5z2JS 358 9,29623
64EYC 266 4,61489
6FH3G 371 8,99581
6T78k 340 9,96709
6T78v 341 9,24949
6T8V4 332 9,40815
6T9Gq 347 10,34816
6Thw4 348 10,34816
6UeXY 362 10,33875
6Uf0K 451 5,41740
6W3Yj 356 10,32753
6Xg2x 349 9,85639
6bIzO 260 4,69822
6iXFI 255 4,96826
6o3Ac 274 5,27525
7M4M6 255 4,96826
7OAY2 249 4,59051
7Oibd 259 4,53492
7l1Hj 364 10,19995
7o64w 381 10,58676
7o7Jw 349 10,07939
7pyDl 350 9,81043
7ucUP 375 11,10489
7ulyq 384 11,18264
7ydXa 342 10,06953
7zcFn 347 10,18338
8Hchj 358 4,83048
Okt4 233 8,95094
Yqx4 373 9,91442
bqKq 356 9,93711
gvvD 355 10,80002
ytLP 250 6,02950
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16230
4OkwF
 5 52,0% 344 5.715E-130
2 phalp2_28888
5nEcp
 3 42,6% 239 2.427E-69
3 phalp2_14460
4HBgJ
 2 36,8% 304 9.641E-50
4 phalp2_3417
3R9PN
 1 30,9% 343 1.670E-44
5 phalp2_30680
6VuKS
 1 27,7% 385 1.084E-41

Domains

Domains [InterPro]
Disordered region
Transgly
NLPC_P60
LysM
Representative sequence (used for alignment): 4Jmb8 (342 AA)
Member sequence: G9FHH0 (358 AA)
1 342 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877, PF01476, PF06737

Taxonomy

  Name Taxonomy ID Lineage
Phage Rhodococcus phage REQ1
[NCBI] 		1109712 No lineage information
Host Rhodococcus equi
[NCBI] 		43767 Actinobacteria > Actinobacteria > Corynebacteriales > Nocardiaceae > Rhodococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
JN116825 [NCBI]
CDS location
range 26131 -> 27207
strand +
CDS
ATGGGCCACAAGGGAAAGCATCGCAAGCAAACCAACTCCAACGCAAAGCGTTTCGTAGCGACAGCAACCGGCGTCGGGGCACTCGGCCTCGTCTCCGCTGTCGCAGGCACTCCGGCCGCGTCGGCGCACGACTGGTCCGGAGTCGCCCACTGCGAGTCGTCCGGAAACTGGAGCATCAACACCGGCAACGGGTTCTACGGCGGCCTGCAGTTCACGCAGTCCACCTGGGACGCGTTCAAGCCTGAAGGCGCAGCCTGGCGCGCTGATCTGGCCACGATGGCGGATCAGATCGCGGCAGCGGAAGCAACCCTGAAGGTGCAGGGCATCGGCGCGTGGCCGGTGTGTGGGGCGTACCTCGGCTGGGGTGGAGTCACTCCCGGCGTCGGGACCGCGCCCTCCGCGCCGTCGTACGTCGAGCCTGCGCCCGCCCCCGCACCCGCCGCATCGTGGGTGCAGCCGGTCACCGGCACGAAGTCGCAGGGCTTCCACGGTGGCCACAACGGCGTCGACATCGCTGCCCCGATCGGCACCCCGATCTACGCAGCGGCGTCCGGCTCCATCGACCTCGCTGGGTTCAACAACGACCCCGGCGGCTACGGCAACTACATCCAGCAGACCGCCGACAACGGCGCGAAGATCCAGTACGGCCACATCTCCGAGATCTACGTCAGCGCAGGCGACTACGTCACCGCTGGCACCCTGATCGCGGCGGTCGGCAACGCTGGCTCCTCGACCGGTGCTCACCTGCATCTGCGGATCAACGCCGAGGATCCGGAGGCGTACCTGATCAACCAGGGCGTCGCGCTGGACTGGTCCGGCCCCAGCGGCCTGCCCGTCACTCCGGCACCGGCACCTGTGTCCGCCCCTGGGGAAGAGGTGGCGGTCGAGGACGTTCCGGTCTACCTGGCCCCGGCTCCCGAGGGAGTCGAGACGGTGACCGTCGTTCCGGGAGACACGCTTTCGCACATCGCTGAGGTGTTCGGGATCGACTCCTGGGAGACCCTCTGGGACCTGAACAAGGATGTGGTCGAGAACCCGCATCTGATCTACCCCGGCCAGGTACTCCGCCTGGCCTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00023eec61_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (4Jmb8) rather than this protein.
PDB ID
4Jmb8
Method AlphaFoldv2
Resolution 74.54
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50