Protein

Protein accession
A0A221SAT8 [UniProt]
Representative
8H6xM
Source
UniProt (cluster: phalp2_2838)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MEVTMGQDMRGNIAAIALCIGVATATVVTALSETGNLPLDNPKPVAERPSTSPSATPSKSETPKAVVQPKPSLSSLLSRTPLPKPTPKEFAKEKVGTKQFKCLNKLWSHESEWEHDAVNSTSGAYGIPQALPGSKMAKAGGDWRTNPFTQVEWGVDYIEDRYGSPCNAWAFFQRNNWY
Physico‐chemical
properties
protein length:178 AA
molecular weight:19395,7 Da
isoelectric point:8,41
hydropathy:-0,51
Representative Protein Details
Accession
8H6xM
Protein name
8H6xM
Sequence length
222 AA
Molecular weight
24604,39570 Da
Isoelectric point
9,84524
Sequence
MKKSVSIIASLMLIGTSFSAVAASDDEPSKRPVAIERQTTHVSRDYVRPTLVVDDIVEAKRAMQKSLEDQRVAAEKKREKERAERAAAREAAHKKAEAERAEKARQQKREQQKNKVPAPREKTYSEPTGGIKGYAARLVGQSQFGCLNNLFNRESGWNPYAANPSSGAYGIPQALPGSKMASAGSDWRTNPYTQVRWGVSYIKSRYGTPCSAWAHSQSVGWY
Other Proteins in cluster: phalp2_2838
Total (incl. this protein): 33 Avg length: 195,6 Avg pI: 9,32
Protein ID Length (AA) pI
8H6xM 222 9,84524
3MEda 302 9,08858
5IQfP 198 10,36756
6Qy8Z 244 11,07884
7tNiZ 222 10,82348
7zk69 235 10,86481
A0A2L1IVL5 222 9,84524
A0A482JAJ5 184 9,13364
A0A222Z0D9 179 9,22692
A0A223FZT4 182 8,75972
A0A0A0RLZ4 178 8,95803
A0A222YXT5 182 8,41417
A0A514DJX8 174 8,40121
A0A514U1R7 179 9,05595
A0A5Q2WI41 178 9,49073
A0A6M3SXR2 175 8,89833
A0A222YZF0 179 9,07594
A0A4D6E0Z7 222 9,73900
A0A6G8R1D9 220 9,92525
A0A6G8R318 220 10,03523
A0A7G4AVY1 205 10,09699
A0A7G9UW82 178 8,88486
A0A7G9W1E8 178 8,88486
A0A890UQZ0 182 8,75972
A0AA49H0I3 179 9,20565
A0AA96H3R4 179 9,20565
A0AA96HC74 179 9,20565
A0AA96HHJ2 182 8,75972
A0AA96K4Z7 179 9,07588
A0AAE8YCH7 174 8,40121
A0AAX4NQC1 182 8,75972
A0AAX4RA00 182 8,75972
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_31748
3XC52
 23 39,7% 166 1.391E-37
2 phalp2_14669
5XZKO
 7 46,0% 165 8.107E-36
3 phalp2_3059
20Jol
 1 27,1% 151 1.777E-05

Domains

Domains [InterPro]
Disordered region
Unannotated
Unannotated
Representative sequence (used for alignment): 8H6xM (222 AA)
Member sequence: A0A221SAT8 (178 AA)
1 222 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Warpy
[NCBI] 		2015805 Stanwilliamsviridae > Samistivirus > Samistivirus jay2jay
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF358541 [NCBI]
CDS location
range 17473 -> 18009
strand -
CDS
TTGGAGGTAACAATGGGTCAAGATATGAGGGGCAACATAGCCGCTATCGCTCTTTGCATCGGAGTAGCTACAGCAACGGTTGTAACTGCTTTGTCAGAGACTGGTAACCTGCCTTTGGACAATCCAAAGCCGGTGGCTGAACGTCCATCAACATCGCCATCAGCAACACCAAGCAAAAGTGAGACCCCAAAGGCTGTCGTGCAGCCCAAGCCGTCCTTGAGTTCACTGCTTAGTCGTACACCTTTGCCGAAGCCTACTCCGAAGGAGTTTGCTAAAGAAAAGGTCGGTACAAAGCAGTTCAAGTGTCTCAATAAACTCTGGAGCCATGAGAGTGAATGGGAACATGATGCAGTGAACTCAACTTCTGGTGCTTATGGGATTCCTCAAGCTCTACCGGGCTCGAAAATGGCTAAGGCTGGTGGAGACTGGAGAACCAATCCGTTTACCCAGGTGGAATGGGGCGTGGATTACATCGAAGACCGCTACGGCTCTCCTTGTAATGCATGGGCATTCTTTCAGCGTAACAATTGGTACTAA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000b8b8e71_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8H6xM) rather than this protein.
PDB ID
8H6xM
Method AlphaFoldv2
Resolution 79.78
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50