Protein

Protein accession
R9R1H1 [UniProt]
Representative
2kZPk
Source
UniProt (cluster: phalp2_34143)
Protein name
Transglycosylase SLT domain-containing protein
Lysin probability
99%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MAQLYQQEFKTQEKAKYEHIRQAKEKALEEQRISEENKRRVEAEKQAESDRIAREHDKTTKQPDTERTQEVSDENENEGGVPNTATSDTIGSDWSSVSPEIAANYMASKTGVTAGKWLDVIYKESSGNPYVENELSCWGLLQIMQSVHGQVSNLSPQDYLDKAVSIYQGSGGTAWVTW
Physico‐chemical
properties
protein length:178 AA
molecular weight:20062,7 Da
isoelectric point:4,85
hydropathy:-0,97
Representative Protein Details
Accession
2kZPk
Protein name
2kZPk
Sequence length
142 AA
Molecular weight
15822,21040 Da
Isoelectric point
4,93899
Sequence
VAQLYEQEFKTQEKAKYEHIRQSKEKALEEQRSEADRIEREQEVVPNTATNGNIGTDWSSVSPEIAANYIASKTGVGASKWLDVIYKESSGNPYVENPIGCWGLLQINQSVHGQVSQLSPQEYLDKAVSIYQGSGGTAWATW
Other Proteins in cluster: phalp2_34143
Total (incl. this protein): 47 Avg length: 176,1 Avg pI: 5,09
Protein ID Length (AA) pI
2kZPk 142 4,93899
1GxQb 166 5,03488
1GxRI 139 4,93831
1GxUe 139 5,04551
7PPNp 181 4,78166
7XvNx 153 4,90960
7YygB 162 4,61450
87adR 118 4,75006
8kQqL 180 5,07626
Q09YE6 178 5,03550
A0A2Z2XRS9 194 5,01550
C7T210 151 4,94212
R9R0T9 178 4,91336
A0A343JQU3 175 4,99458
A0A126HC71 175 5,47021
R9R197 194 5,17561
A0A126HAG9 158 5,22603
A0A126HC27 169 5,00748
A0A126H9U3 158 5,39450
A0A2H4ESA4 207 5,32459
O80124 207 5,49402
A0A2H4ESX4 189 4,87829
R9R181 178 5,22660
R9R1K3 183 5,03726
A0A649V4J3 188 5,11496
A0A650ETD1 181 5,89775
A0A2K8IK61 194 4,96769
A0A343JN90 168 6,10476
A0A343JPM9 178 5,10865
A0A343JQI8 194 5,18050
A0A343JQP2 174 4,93632
A0A096XV00 175 5,47021
A0A126HA95 158 5,22603
A0A2H4ET51 158 5,22603
A0A2Z2QIL8 194 4,94831
A0A2Z2XQR8 196 4,94831
A0A2Z2XS21 194 5,01550
A0A2Z2XT30 196 4,94831
A0A2Z2XT83 194 5,01550
A0A2Z2XTD5 194 5,01550
A0A2Z2XXU0 194 5,01550
A0A7T0MF78 178 4,95689
B3TJQ7 194 5,01550
C7T1V8 165 4,91245
R9R0S7 178 4,91336
R9R1F1 178 5,22660
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20830
6ot2T
 127 65,9% 185 2.476E-71
2 phalp2_9122
5R0vB
 13 84,8% 99 6.796E-58
3 phalp2_4946
6Ee5z
 2 26,1% 126 7.564E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 2kZPk (142 AA)
Member sequence: R9R1H1 (178 AA)
1 142 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactococcus phage P680
[NCBI] 		1262537 Skunavirus > Skunavirus P680
Host Lactococcus lactis subsp. lactis
[NCBI] 		1360 Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus > Lactococcus lactis
Host Lactococcus lactis subsp. lactis Il1403
[NCBI] 		272623 Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus > Lactococcus lactis

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KC182551 [NCBI]
CDS location
range 17427 -> 17963
strand -
CDS
GTGGCACAATTATATCAACAAGAGTTTAAAACGCAAGAGAAAGCAAAATATGAGCATATAAGGCAAGCTAAGGAGAAAGCACTTGAAGAACAACGAATTAGTGAAGAAAATAAACGAAGAGTTGAAGCTGAAAAACAAGCCGAATCTGACAGAATCGCAAGAGAACATGATAAGACAACTAAACAACCTGACACCGAAAGGACGCAAGAAGTTAGCGATGAAAATGAAAATGAGGGAGGTGTACCAAACACAGCAACTAGTGACACTATTGGAAGTGATTGGTCTAGTGTAAGTCCAGAAATAGCTGCGAATTATATGGCAAGCAAGACAGGAGTAACTGCTGGTAAATGGCTTGATGTTATTTATAAGGAGTCGAGTGGAAACCCTTATGTTGAAAATGAGTTATCATGCTGGGGACTATTACAGATAATGCAAAGCGTGCATGGTCAGGTATCTAACTTAAGTCCACAAGATTATTTAGACAAAGCAGTAAGTATATATCAAGGTTCAGGCGGTACAGCTTGGGTGACTTGGTAA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000351dead_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (2kZPk) rather than this protein.
PDB ID
2kZPk
Method AlphaFoldv2
Resolution 77.39
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50