Protein

Protein accession
R9ZWL8 [UniProt]
Representative
4QI18
Source
UniProt (cluster: phalp2_28770)
Protein name
Glycosyl hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNLDYYKNIVRNHPEEFELFKNKFFPIVMKWEGGGELHNVKGDSGGWTIWGIAYNYNKALFDDFNDFKDTTREEASYIAFVKYYLAANAELVPMDAKLYYFDMCYNMGVSRGIKILQKCIGVNADGRIGNITKSKIHNVTECCLMIERNKFYNRLVENNYKMGKFIKGWLNRSKGIFDFKY
Physico‐chemical
properties
protein length:181 AA
molecular weight:21270,2 Da
isoelectric point:8,88
hydropathy:-0,42
Representative Protein Details
Accession
4QI18
Protein name
4QI18
Sequence length
180 AA
Molecular weight
21150,14150 Da
Isoelectric point
9,25800
Sequence
MKNLSLYIRNREQYPIEYQAFKQMFKHTLKWEGGSKLHKVDGDSGGWTLYGVAYSKNKHLFESLDDFFDTTYDEAVLVAFTEYYLAIKAHLLPKDAQLMYFDMAYNLGAYRATRYMQRCAGVIDDGIIGKITISKMHCVTKECLYEQRNNWYNYLARTKSWAKKFIKGWLNRSKAILQIG
Other Proteins in cluster: phalp2_28770
Total (incl. this protein): 87 Avg length: 187,4 Avg pI: 9,32
Protein ID Length (AA) pI
4QI18 180 9,25800
14AJc 191 9,17786
18ARw 192 9,28340
18sX5 192 8,70447
1Ks0d 191 8,93875
1McbR 192 9,26806
1MkSm 191 9,29965
1QIAA 192 9,16304
1dTFa 190 9,17774
1dUQ1 191 9,59620
1glGc 192 9,50059
1gm2u 192 9,41163
1oHlg 192 9,29952
1rJDD 191 9,09670
1spht 192 9,36012
26Ncc 191 9,99752
28hsm 187 9,97888
28jJ2 191 10,02034
2B0Ez 174 9,82287
2ZQXj 193 9,37649
2gvMq 186 9,40989
2ivL 192 9,10985
2n4To 181 9,30035
301ML 192 9,19282
37YQg 177 9,08200
3j5C5 181 9,50562
4Ge0Y 192 9,08136
4WgIY 191 9,39383
4Wgra 191 9,20836
4ZPBF 192 9,36012
4kSkM 187 9,19282
4mUU1 192 9,28366
4nD0t 192 9,36012
4nHCW 179 9,25703
4rrq5 192 9,36012
4uhTf 165 9,06711
4xQQE 191 9,14866
51kqX 193 9,31679
59Izn 193 9,58801
5fn8v 192 9,17754
5gnHd 192 9,29952
5iWFm 192 9,29971
5iskS 192 9,28366
5tl3a 192 9,28366
5xaY8 192 9,14885
5xzX4 192 9,29965
5y4fq 192 9,25316
5zXBD 187 9,97888
6BWh5 193 9,47835
6C0Wf 191 9,20862
6Iytl 192 9,28353
6PDVW 190 9,34426
6SVbK 180 9,21197
6SsAP 180 9,02643
6Suy0 180 9,23950
79wpQ 181 9,40041
7FiIQ 192 9,10985
7LR57 182 9,39725
7PIQv 193 9,31679
7UPwB 181 9,84131
7Vmre 164 9,76098
7aSTl 181 9,00083
7aT1c 181 8,72871
7rszK 191 9,88244
81occ 191 9,95323
84CK8 192 9,06672
85AEN 187 9,94981
8B7dk 185 10,10582
8EV7R 181 9,73294
8FoKS 179 9,79302
8GYKd 181 8,51635
8GYKk 181 8,88421
8d5t 188 8,91109
8dW3C 191 9,02585
8hzR9 183 9,27160
8lstk 181 9,32318
TkAq 192 9,32891
U9tL 192 9,28359
bLup 178 9,36798
lIiw 191 9,29965
vcDz 191 9,95323
A0A1B0WKU4 193 9,31679
S0A5P7 181 9,00083
R9ZZ38 181 8,72871
S0A1T1 181 8,51635
A0A6M2VBZ5 193 9,22512
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12384
8ztAB
 22 29,8% 154 7.725E-24
2 phalp2_1444
1DO8y
 138 30,0% 180 1.056E-23
3 phalp2_30611
6uqQp
 1606 26,7% 168 1.974E-23
4 phalp2_23735
PTzZ
 309 28,9% 166 2.698E-23
5 phalp2_23908
1Le4q
 257 34,1% 164 3.688E-23
6 phalp2_28839
4XJZ6
 27 27,2% 165 4.490E-22
7 phalp2_40381
3TbBc
 289 31,3% 137 2.922E-21
8 phalp2_34912
4ndwJ
 921 29,3% 160 2.594E-20
9 phalp2_13016
426A1
 31 26,3% 163 2.594E-20
10 phalp2_20399
37U0b
 4 24,6% 158 2.594E-20

Domains

Domains [InterPro]
GH108
Representative sequence (used for alignment): 4QI18 (180 AA)
Member sequence: R9ZWL8 (181 AA)
1 180 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05838

Taxonomy

  Name Taxonomy ID Lineage
Phage Cellulophaga phage phi19:3
[NCBI] 		1327971 Pachyviridae > Baltivirus > Baltivirus phi19tres
Host Cellulophaga baltica
[NCBI] 		76594 Bacteroidetes > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Cellulophaga >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KC821608 [NCBI]
CDS location
range 43815 -> 44360
strand +
CDS
ATGAACTTAGATTATTACAAAAATATAGTGAGAAATCACCCAGAGGAATTTGAGCTATTTAAGAATAAGTTCTTTCCTATTGTGATGAAGTGGGAAGGTGGAGGCGAACTACACAACGTTAAAGGTGATTCAGGCGGTTGGACTATTTGGGGAATAGCATACAACTACAACAAAGCTCTATTCGATGATTTTAATGACTTTAAAGACACAACAAGAGAAGAAGCATCTTATATTGCATTTGTAAAGTATTACTTGGCGGCCAACGCAGAATTGGTACCAATGGATGCGAAGCTATACTATTTTGATATGTGCTATAACATGGGCGTATCAAGAGGTATTAAGATACTTCAAAAATGCATAGGTGTTAATGCCGATGGTAGAATTGGAAATATTACTAAGTCAAAAATACACAATGTAACAGAGTGCTGTTTGATGATTGAAAGAAATAAGTTCTATAATAGGCTAGTTGAAAACAACTATAAAATGGGGAAATTCATTAAAGGTTGGTTAAATAGAAGTAAGGGAATATTTGATTTTAAATACTAA

Gene Ontology

Description Category Evidence (source)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00035189b8_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (4QI18) rather than this protein.
PDB ID
4QI18
Method AlphaFoldv2
Resolution 93.25
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50