Protein

Protein accession
A0A6B9LGN2 [UniProt]
Representative
4KkLG
Source
UniProt (cluster: phalp2_40545)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MELKMQKMSRAKKVKYIVIHCQAGTGTREAMEKFWYSPKPKGLGWKSPGYHRWVDFDGTVHQLQNFNLPTNGVAGFNEECIHISYRGGIENLGTKEKPIWKGKDTRTQAQKDAILKQIMLAIQWLKDNGNDLQNVMILGHYHFSDDKNKNGAIESWERIKECPCFDAYEEYKPFFLSNVKAPNYSKLKLPKNR
Physico‐chemical
properties
protein length:193 AA
molecular weight:22399,5 Da
isoelectric point:9,38
hydropathy:-0,77
Representative Protein Details
Accession
4KkLG
Protein name
4KkLG
Sequence length
108 AA
Molecular weight
12019,61770 Da
Isoelectric point
9,09844
Sequence
MRTAKGITHIAIHCSAGFGNRQSIEAFWKTLGWKSPGYHRLIEVDGTVHELLDFSKTSNGVFGFNNAIINIAYIGGVEKKGNKWIAKDTRTLEQKCALDHCISEAKAW
Other Proteins in cluster: phalp2_40545
Total (incl. this protein): 4 Avg length: 162,3 Avg pI: 9,05
Protein ID Length (AA) pI
4KkLG 108 9,09844
A0A1B0WN79 174 8,86042
A0A1B0WNC7 174 8,86042
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11611
1k5JO
 2203 50,4% 105 1.362E-26
2 phalp2_37043
NDSw
 22 56,4% 78 9.581E-23
3 phalp2_26108
2kvR
 27 29,4% 78 1.083E-06
4 phalp2_3887
6RreM
 7260 31,1% 93 3.079E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 4KkLG (108 AA)
Member sequence: A0A6B9LGN2 (193 AA)
1 108 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Flavobacterium phage vB_FspS_laban6-1
[NCBI] 		2686250 Duneviridae > Labanvirus > Labanvirus laban
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN812211 [NCBI]
CDS location
range 31575 -> 32156
strand -
CDS
ATGGAACTAAAAATGCAGAAAATGAGTAGAGCTAAAAAAGTAAAGTACATCGTGATTCATTGTCAAGCAGGCACAGGAACACGAGAAGCAATGGAAAAATTTTGGTATTCTCCAAAACCTAAAGGGTTAGGATGGAAATCACCAGGTTATCATCGTTGGGTTGACTTTGATGGAACCGTACATCAACTTCAAAATTTTAATTTACCAACAAATGGGGTTGCTGGATTTAATGAAGAATGTATCCATATTTCATATCGTGGTGGTATTGAAAATTTAGGAACAAAAGAGAAACCTATTTGGAAAGGTAAAGATACCCGAACACAGGCGCAGAAAGATGCTATTTTAAAACAAATTATGTTAGCTATTCAATGGCTAAAAGATAACGGAAATGATTTGCAAAATGTAATGATTCTTGGGCACTATCATTTTTCAGATGATAAAAATAAGAACGGAGCAATTGAATCATGGGAAAGAATTAAAGAATGTCCTTGTTTTGATGCTTACGAAGAATATAAGCCATTCTTTTTATCGAATGTTAAAGCTCCAAATTATTCAAAATTAAAACTTCCAAAAAACAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4KkLG) rather than this protein.
PDB ID
4KkLG
Method AlphaFoldv2
Resolution 96.60
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50