Protein

Protein accession
A0A1W6DXC5 [UniProt]
Representative
7FpgX
Source
UniProt (cluster: phalp2_28794)
Protein name
NlpC/P60 family protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 77% (predicted by ML model)
Protein sequence
MQNPNADDVVAEARKWLGTRWVHQGRNEFGIDCAGLLVKVHEGLGLPVEDETNYRRTPTQTRFLEHIRNQTDYIDAPEPGAIAVFREQTFPCHTGFFAMKNGVLTIIHSYIVAKQVVEETFMHDWPRRLVEARRLRGVSY
Physico‐chemical
properties
protein length:140 AA
molecular weight:16150,1 Da
isoelectric point:6,59
hydropathy:-0,44
Representative Protein Details
Accession
7FpgX
Protein name
7FpgX
Sequence length
112 AA
Molecular weight
12421,17610 Da
Isoelectric point
5,61594
Sequence
MGVDCVGLVLCSLNDIGIPAPDMQGYRRTPDPIFVEHIRNNSLPSNEMRPGNLGIFRDGTQPCHVGIFATLHGQTSLIHAYAGTGLVMEEVFIHDWPKKLIETRSFLGLEYI
Other Proteins in cluster: phalp2_28794
Total (incl. this protein): 23 Avg length: 138,6 Avg pI: 7,49
Protein ID Length (AA) pI
7FpgX 112 5,61594
18Rvb 149 8,90639
2cwJl 165 8,73510
2fYMg 146 6,17450
2qglF 146 8,66038
3IwG 146 8,78074
3m3tV 143 8,97537
4DTPR 137 6,58073
4KKQS 138 5,89298
4UcPV 145 6,64342
4WnQj 138 8,68778
4XFB6 99 9,15653
5dQYN 132 9,09651
6RWkd 114 7,11496
6TnMX 138 6,57430
8Jxjv 149 8,90639
DLFg 138 7,87999
EgN2 138 6,27255
Pwhp 146 6,06349
dor3 148 6,42834
A0A385ECX0 140 6,94660
K4JSA9 140 7,63913
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28766
4PrSU
 248 42,4% 113 1.628E-26
2 phalp2_38771
1fCGD
 1216 34,8% 112 2.251E-19
3 phalp2_36512
1oWEW
 304 34,1% 117 6.656E-17
4 phalp2_19724
4MrB2
 69 33,0% 118 1.718E-16
5 phalp2_33260
5BBWg
 36 33,6% 125 8.676E-13
6 phalp2_20469
3OKnd
 174 29,0% 124 7.900E-12
7 phalp2_39520
5tjGv
 29 34,0% 94 1.350E-10
8 phalp2_38782
1j4UU
 4 35,7% 109 1.350E-10
9 phalp2_39389
4K1MK
 12 28,9% 121 1.350E-10
10 phalp2_201
5IaYc
 48 32,9% 82 1.850E-10

Domains

Domains [InterPro]
NLPC_P60
Representative sequence (used for alignment): 7FpgX (112 AA)
Member sequence: A0A1W6DXC5 (140 AA)
1 112 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage Sphingobium phage Lacusarx
[NCBI] 		1980139 Lacusarxvirus > Lacusarxvirus lacusarx
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KY629563 [NCBI]
CDS location
range 19900 -> 20322
strand +
CDS
ATGCAAAATCCTAATGCTGATGATGTGGTGGCCGAGGCGCGTAAGTGGCTCGGCACACGGTGGGTCCATCAGGGCCGCAACGAGTTCGGGATCGATTGCGCCGGGCTTCTCGTGAAGGTCCATGAAGGCCTTGGCCTCCCGGTAGAGGACGAAACCAACTACCGGCGCACACCCACCCAGACCCGGTTTCTGGAGCACATCCGAAACCAGACCGATTACATCGACGCCCCCGAGCCGGGCGCCATCGCCGTCTTTCGGGAACAGACCTTCCCCTGTCACACCGGATTCTTCGCCATGAAGAACGGCGTCCTCACCATCATCCATTCCTACATCGTGGCCAAGCAGGTGGTCGAAGAGACCTTCATGCACGACTGGCCCCGCCGCCTCGTAGAGGCGCGCCGTCTTCGCGGAGTTTCCTACTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000a1d5526_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7FpgX) rather than this protein.
PDB ID
7FpgX
Method AlphaFoldv2
Resolution 83.69
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50