Protein

Protein accession
A8ATW4 [UniProt]
Representative
7cJ8s
Source
UniProt (cluster: phalp2_13826)
Protein name
PlyA006
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MALTEAWLIEKANRKLNVSGMNKSVADKTRNVIKKMAKKGIYLCVAQGYRSSAEQNALYAQGRTKPGAVVTNAKGGQSNHNYGVAVDLCLYTSDGKNVIWESTTSRWKTVVSAMKAEGFEWGGDWKSFKDYPHFELYDAAGGEKAPSTSASKPATSTSSNKNVYYTENPRKVKTLVQCDLYNSVDFTEKHKTGGTYPAGTVFTISGMGKTKGGTPRLKTKSGYYLTANKKFVKKI
Physico‐chemical
properties
protein length:235 AA
molecular weight:25747,0 Da
isoelectric point:9,75
hydropathy:-0,61
Representative Protein Details
Accession
7cJ8s
Protein name
7cJ8s
Sequence length
286 AA
Molecular weight
32940,74500 Da
Isoelectric point
9,85859
Sequence
MALTEAWLIEKANRKLNVAGMNKTTSDKTRNVIKKMAKQGIYLCVAQGYRSKTEQNALYAQGRTKPGSIVTNAKGGQSNHNFGVAVDLCLYSNDGKKVIWESTTSRWKKVVAAMKAEGFKWGGDWKIFKDYPHFELCDAVSGEKVPAQKNKNPNRHEGKVVDSAPLLPKMDFKTNPVRMYKAGTKFLVYEHNKYWYKTYINNKLYYMYKSFCVVAGKKDSKGRLPVRIKSAKDLRIPVWNNTKLNSGKIKWYKPGTKLAWYDNKKGYLELWYPADGWYYTANYFLK
Other Proteins in cluster: phalp2_13826
Total (incl. this protein): 52 Avg length: 277,3 Avg pI: 9,60
Protein ID Length (AA) pI
7cJ8s 286 9,85859
72KQ4 226 9,73494
750hn 286 9,72746
76rWj 287 9,50930
76rXu 289 9,55475
7AUXQ 289 9,56409
7AUZ7 308 9,50865
7BZgo 308 9,54269
7Bagj 289 9,56384
7PQOq 291 9,85627
7QEiH 229 9,68994
7cCn6 235 9,71959
7cEc7 235 9,85336
7cLGY 236 9,77387
7dCGn 308 9,54295
7db8o 308 9,45488
7eQ9V 289 9,49995
7eTbd 285 9,64539
7kXfG 235 9,74764
7klXt 289 9,47919
7krsd 235 9,76279
7lz1f 308 9,49975
7lz2h 308 9,63133
7mt1g 308 9,56932
7mt5T 289 9,50897
7mxzW 230 9,35464
7oIk8 287 9,51877
7oJsq 287 9,54707
7oQ5p 308 9,48286
7oXPM 257 9,65706
7ozcZ 235 9,74744
7rclY 226 9,31099
7tZzi 257 9,61541
7vbp8 308 9,60252
7vplZ 235 9,74744
7wd0R 235 9,80527
7wdcY 289 9,52819
7x3Xd 287 9,52851
7x43p 235 9,74744
8IiQV 235 9,68291
8J2XZ 289 9,56384
8J2Y0 289 9,52793
A0A2U8UV78 289 9,56409
A0A2U8UUL2 308 9,45488
R4ICC5 308 9,56932
Q0PRU8 287 9,51877
Q37979 289 9,52793
A0A059T7X1 316 9,54346
A0A0B5CTW5 316 9,52593
A0A0B5D123 316 9,50794
A0A2U8UV87 308 9,52644
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12448
qevc
 108 35,7% 204 2.008E-25
2 phalp2_2393
7PQjE
 101 28,0% 228 5.144E-17

Domains

Domains [InterPro]
PET_M15
PSA_CBD
Representative sequence (used for alignment): 7cJ8s (286 AA)
Member sequence: A8ATW4 (235 AA)
1 286 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13539, PF18341

Taxonomy

  Name Taxonomy ID Lineage
Phage Listeria phage A006
[NCBI] 		330399 No lineage information
Host Listeria monocytogenes
[NCBI] 		1639 Firmicutes > Bacilli > Bacillales > Listeriaceae > Listeria >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
DQ003642 [NCBI]
CDS location
range 18484 -> 19191
strand +
CDS
ATGGCATTAACAGAGGCATGGTTAATCGAAAAAGCAAATCGTAAATTAAACGTTTCTGGAATGAATAAATCTGTAGCAGATAAAACCCGAAATGTAATTAAAAAAATGGCGAAAAAAGGAATCTATTTGTGTGTTGCGCAAGGTTATCGCTCGTCAGCAGAACAAAATGCACTGTACGCACAAGGCAGAACAAAACCTGGCGCAGTTGTCACAAATGCGAAAGGTGGACAATCTAATCATAATTACGGTGTAGCGGTAGACTTGTGTTTATACACAAGCGACGGAAAAAATGTTATTTGGGAGTCGACAACTTCGCGCTGGAAAACAGTTGTATCAGCTATGAAAGCAGAAGGATTTGAGTGGGGCGGAGATTGGAAGTCTTTTAAAGATTATCCGCATTTTGAATTATATGATGCTGCTGGCGGTGAAAAAGCCCCATCGACAAGTGCAAGCAAACCTGCGACTTCTACAAGCTCAAATAAGAACGTTTACTACACAGAAAATCCGCGAAAAGTTAAAACACTAGTACAGTGTGATCTATACAATTCAGTAGACTTTACTGAGAAGCATAAAACCGGTGGCACATATCCGGCTGGCACAGTCTTCACGATTTCGGGGATGGGGAAAACGAAAGGCGGGACACCTCGCTTGAAGACGAAGAGCGGTTACTATCTCACTGCTAACAAGAAGTTTGTTAAAAAGATTTAG

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00015c02a4_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7cJ8s) rather than this protein.
PDB ID
7cJ8s
Method AlphaFoldv2
Resolution 94.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50