Protein

Protein accession
A0A5J6B8K8 [UniProt]
Representative
7sWTO
Source
UniProt (cluster: phalp2_13860)
Protein name
Lytic murein transglycosylase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRISNMSRWAQGYFRRRNERRMDRFQSATHRPLQRAAQAILWLHAAFVALIVASCTYGTTAHAQPIPREAQRYQLTLKREAQLAWGLQAPVATFAAQVHQESRWRLNARSPVGAEGLAQFMPATSNWIGGLYPSLADRAPTNPTWALRALVTYDKWLADRIRADDECQDMAFALSAYNGGLGWVYKRQKLSDQPGLCLGATCQINPGITAAYQQENQHYPELILRRYEPMYASWGNGACS
Physico‐chemical
properties
protein length:240 AA
molecular weight:27146,6 Da
isoelectric point:9,67
hydropathy:-0,42
Representative Protein Details
Accession
7sWTO
Protein name
7sWTO
Sequence length
286 AA
Molecular weight
30696,64470 Da
Isoelectric point
7,64339
Sequence
MRTATHLFAEVRAVVLACALMAALNFAGCTPTPVETATVAQPTSQPANITPVSESVEPAESALVNDAVVLSADVLPTQAVQAQLPETPITAVTPEVTESLVAKSANEPHPRAGPYKHVLIQQSRNVWGLGAPVASFAAQIHQESRWNATAHSPVGAVGLTQFMPATARWIGTYDTQLAPVDVYNPRWAMRALAVYDKFLYDKVAGINPCERLAFAMSAYNGGLGWVNKRKARSSTPNVCFGETCDINPGITASNQRENANYPKLILKQFEPMYVRAGWGVGACHAR
Other Proteins in cluster: phalp2_13860
Total (incl. this protein): 4 Avg length: 240,0 Avg pI: 9,21
Protein ID Length (AA) pI
7sWTO 286 7,64339
B5TA73 223 9,58859
U6C6A5 211 9,93015
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_414
7u6ty
 1517 50,2% 191 3.999E-76
2 phalp2_25478
37Ryn
 12 43,2% 259 9.192E-55
3 phalp2_39610
6EkfA
 1 34,8% 316 1.502E-45
4 phalp2_6836
8s2Bn
 9 33,8% 207 5.154E-40
5 phalp2_22779
8oQiz
 5 30,0% 180 1.408E-18
6 phalp2_27428
4QEUo
 17 26,8% 227 1.297E-11
7 phalp2_17547
5JCkz
 2 25,7% 202 4.185E-04

Domains

Domains [InterPro]
Disordered region
SLT
Representative sequence (used for alignment): 7sWTO (286 AA)
Member sequence: A0A5J6B8K8 (240 AA)
1 286 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01464

Taxonomy

  Name Taxonomy ID Lineage
Phage Curvibacter phage TJ1
[NCBI] 		2290809 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH766655 [NCBI]
CDS location
range 7053 -> 7775
strand -
CDS
ATGCGGATCAGCAACATGAGCCGATGGGCGCAGGGGTACTTCCGCCGCCGTAACGAGCGGCGCATGGATCGCTTCCAGTCGGCCACCCACCGCCCTCTGCAGCGCGCCGCTCAAGCCATCTTGTGGCTACATGCCGCGTTCGTCGCACTCATCGTTGCATCCTGCACTTACGGCACCACCGCCCATGCACAGCCCATCCCACGCGAAGCCCAGCGCTACCAGCTCACACTGAAGCGCGAAGCCCAGCTCGCTTGGGGACTGCAGGCGCCGGTTGCCACCTTTGCTGCACAGGTTCATCAGGAGAGCCGCTGGCGCCTGAACGCTCGCTCACCTGTAGGTGCAGAAGGCCTTGCGCAATTCATGCCCGCCACTTCCAACTGGATCGGCGGGTTGTACCCCAGCCTGGCAGACCGCGCTCCCACCAACCCCACCTGGGCGCTGCGCGCCCTGGTCACCTATGACAAGTGGTTGGCAGACCGAATCCGCGCCGACGATGAATGCCAGGACATGGCCTTTGCACTTAGCGCCTACAACGGCGGCCTTGGCTGGGTTTACAAGCGCCAAAAGCTAAGCGATCAACCCGGCCTGTGCCTGGGCGCCACATGCCAGATCAACCCCGGCATCACCGCTGCGTACCAGCAAGAAAACCAGCACTACCCAGAGCTGATCCTGCGTCGCTACGAGCCCATGTACGCATCCTGGGGCAATGGAGCCTGCTCATGA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000b555a2f_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7sWTO) rather than this protein.
PDB ID
7sWTO
Method AlphaFoldv2
Resolution 78.24
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50