Protein

Protein accession
A0A1D8KTZ9 [UniProt]
Representative
8H6wD
Source
UniProt (cluster: phalp2_9409)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKDEYLSTLEREVPYWREMNDNQRGALLSFAYNLGAHFYGSAGFSTISRVLREKEWNKVPDALYLYRNPGTSVEAGLTRRRIAEGDLWKS
Physico‐chemical
properties
protein length:90 AA
molecular weight:10463,6 Da
isoelectric point:8,01
hydropathy:-0,67
Representative Protein Details
Accession
8H6wD
Protein name
8H6wD
Sequence length
486 AA
Molecular weight
55285,16440 Da
Isoelectric point
5,47180
Sequence
MKIDFSNFFQYYDGNLKNHVESIALLEREIEKVAPHLLQDEAEWVKLYRNTAQVDKPDKVIALPVPYFPQTDNYTQPERTCNSSSCAMCLEYFRPGTLVGSKGDDAYIRKVFAVGDTTDHSVQTKVLADYGVDSEFNYSLSFDNLDHELENKRPVVIGILHRGSLAHPTGGHMVVVIGKTAEGDYICHDPYGDLNDGYTTNVYNGQSVVYKRNVLEARWTPDGPTSGWGRTFQAKVTAKKSEEGKLPSAGVELIKEFEGLHVLKSDGMIHAYPDPLSGGEPWTIGWGSTRDLDGSAFHPGDKITREKADILLEEQLRRDYLSKLEQTIPYWDEMNDNQHGALLSFGYNLGASFYGSPDFNTITRVLRDKEWNKVPDALYLYRNPGTPVEEGLSRRRIRDKTPYRDFTLNINGHDSDIILSDKETRLVYSLYNGAYTCHFDKIIKGKRYVFDSVLANTFYKLNDQCFDGTRLVRGLETGEFYDFRKE
Other Proteins in cluster: phalp2_9409
Total (incl. this protein): 41 Avg length: 390,1 Avg pI: 5,74
Protein ID Length (AA) pI
8H6wD 486 5,47180
127Vl 398 5,02163
13ZHF 401 8,11001
1AwAv 405 4,94672
1SK7x 405 5,10848
1fJBU 398 5,24012
1utto 405 5,21114
1wxwX 407 5,04897
28LDZ 407 5,02487
2ZUMO 395 7,56876
2jwWk 404 5,17447
2s4Cg 397 5,12957
7AgIf 405 5,05000
82jhz 397 8,12825
8H6wE 405 5,05000
8H6wF 405 5,03908
8H6wH 405 5,13508
8H6wS 405 5,13508
8haaL 401 6,76807
8igMQ 389 8,36995
e2f8 405 4,94433
gMwG 401 8,39238
iAph 403 7,62725
A0A0E3I800 486 5,47180
A0A0E3FK51 405 5,05000
F5B3Y3 185 5,94498
A0A0E3IAT3 405 5,05000
A0A0E3F4W2 405 5,03908
A0A0E3G233 405 5,13508
A0A0E3FR35 405 5,13508
A0A0E3EQW1 405 5,05000
A0A0E3FBF9 405 5,08535
A0A0E3FPJ6 405 5,13508
A0A0E3FPV5 405 5,08535
A0A0E3G3E5 405 5,05000
A0A0E3HBI1 405 5,05000
A0A0E3HCU7 405 5,08535
A0A0E3HQI7 405 5,05000
A0A0E3I9S5 405 5,04454
A0A879R2U7 233 8,17035
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10421
20UhE
 95 71,0% 297 9.307E-176
2 phalp2_27442
7D9tM
 13 29,6% 432 1.064E-35

Domains

Domains [InterPro]
Unannotated
PET_C39
GH24
Disordered region
Representative sequence (used for alignment): 8H6wD (486 AA)
Member sequence: A0A1D8KTZ9 (90 AA)
1 486 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CAM7
[NCBI] 		1883368 Kyanoviridae > Mazuvirus > Mazuvirus scam7
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KU686212 [NCBI]
CDS location
range 156765 -> 157037
strand +
CDS
TTGAAGGATGAATACTTATCTACTCTAGAAAGAGAAGTACCTTACTGGAGAGAAATGAACGACAACCAGAGAGGAGCTTTGTTGAGCTTCGCATATAATCTGGGAGCACATTTCTATGGTAGTGCTGGTTTCAGCACAATAAGCCGTGTTCTTCGGGAAAAGGAGTGGAATAAAGTCCCTGATGCGCTATACTTATACCGAAACCCAGGCACAAGCGTAGAGGCAGGCTTGACCCGCAGACGCATTGCCGAAGGTGATCTTTGGAAATCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8H6wD) rather than this protein.
PDB ID
8H6wD
Method AlphaFoldv2
Resolution 79.23
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50