Protein

Protein accession
A0A127AWA8 [UniProt]
Representative
aKO9
Source
UniProt (cluster: phalp2_26137)
Protein name
L-alanoyl-D-glutamate peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAADIKNLHPVVKEKTEQLISIMDKKLTKYKMRITQGYRSIAEQNEIYAQGRTKPGSIVTNAKGGQSYHNYGLAIDFCLISPDGKQASWDMNKDFDGDGVADWKEVVTEAKKLGFDWGGDWSGFKDYSHFEMTFGLSIKDLQNGKRPANSAKPSTGGSSTSTSSSTLKYGSKGSAVKTLQSNLKTLGYNIGKSGVDGIYGNDTVTAVKKFQKDKKLAVDGIAGSATLAAIKKAIDAKKPSTPASSGSAIVPYPGHVIKYGSKGKDVERIQRAVKVNPDGIYGRDTEAAVKAYQKRHGLTADGIVGLKTWNVMF
Physico‐chemical
properties
protein length:313 AA
molecular weight:33761,9 Da
isoelectric point:9,57
hydropathy:-0,53
Representative Protein Details
Accession
aKO9
Protein name
aKO9
Sequence length
234 AA
Molecular weight
26185,80750 Da
Isoelectric point
9,23885
Sequence
MLTLDFVKNKSSAKLQGLHPVVLTATFKLIEMSFAKGVPIVITQGYRSVMEQDALYAQGRTKPGKIVTNARGGRSLHNYGVAIDFALLLPDGKQVSWDMLRDGNANGRRDWDEAVEIAKKLGFEWGGDWKSFVDTPHFQMTFGLTLNDYAAGKRPSAKQVEDAMLRIQPKDNAGEKEDNKLELSKYQRDTLVTALQALLDRKIITDKSWVDKAKNGTLMLTELTWLNTILVANK
Other Proteins in cluster: phalp2_26137
Total (incl. this protein): 109 Avg length: 242,1 Avg pI: 8,00
Protein ID Length (AA) pI
aKO9 234 9,23885
191o2 230 8,90497
1GC7g 234 8,38342
1GWWK 254 9,09599
1GxHR 233 9,21190
1acSz 230 8,78319
1d7So 230 8,55858
1hMdI 271 6,54338
1hNWi 213 7,98849
1lYxC 297 5,77606
2sDlS 210 8,72826
4EEON 231 8,75502
4EqTP 231 8,45021
4Ffsg 224 8,76875
4uFJJ 181 10,03394
5ioAn 249 6,85731
5iqU1 280 5,63231
6CyqR 240 8,91135
6DyZR 262 6,85577
6FrSy 240 8,64967
6S7Ea 253 9,19469
6SjaQ 253 8,93759
6SuoE 255 8,68075
72bCg 217 9,53850
72cn8 257 8,41527
72co2 260 9,22312
75B2s 224 9,39557
75g5e 232 7,76872
76MuT 236 9,06975
76MyF 230 8,45150
78Fc 235 6,73141
7GaDI 199 9,11243
7bkd2 253 8,33056
7bkyY 229 5,85444
7blju 230 6,20582
7cCcX 279 5,88519
7cCdN 236 7,70568
7cQp4 232 9,03513
7cZwz 230 8,78358
7cb1e 235 6,84622
7cdKr 235 5,87257
7cdO2 236 6,10823
7cpm6 233 8,65748
7cpnF 233 8,90491
7d9Jj 280 5,86393
7dCXL 230 8,86964
7ddN2 230 8,88698
7dukt 259 5,50977
7eiFa 230 6,82354
7eiv0 230 8,54356
7eqyf 262 7,10018
7h8KF 230 6,08708
7hrSf 268 9,19147
7lK8G 257 5,74150
7lq7o 232 6,83326
7myNl 251 8,72285
7nTKs 263 5,57934
7nTLD 227 6,84906
7nTU3 238 6,97366
7oghp 233 8,86790
7sVnw 238 6,00313
7t9bd 271 5,77361
7t9cj 230 7,74672
7vARE 244 9,02101
7vARp 244 8,99890
7vnLK 236 6,90028
7vnO2 266 6,02382
7vnOy 279 7,78199
7vnRy 230 8,46381
7vo8q 236 9,22003
7vob7 230 8,78306
7vof9 230 8,76933
7x2xk 236 8,73058
7xR2s 229 5,64942
7xRp1 236 8,73071
7xRsC 236 9,69374
7xjWx 230 8,55871
7xkCN 282 6,85697
7xkEX 230 8,43970
7xkaX 230 8,78358
7xkeG 230 8,98414
7xkok 236 6,84236
7xkqY 251 5,56553
7xkrd 230 8,56006
7y5hJ 223 9,17645
7yPPx 230 8,45318
7yPQC 230 8,79827
7yPRz 301 6,92222
7yQ4H 252 8,92360
7yQ7Q 230 8,78319
7yQav 230 8,98394
7yYFH 273 9,02011
7yYJY 242 7,66175
7yz9w 255 8,29239
7yzdJ 285 6,00717
7z5G0 257 7,69562
7z5Hf 255 8,37356
7zAZk 236 8,73020
7zB1l 253 8,85797
7zHRR 254 8,61912
7zIPV 255 6,35547
7zIR4 230 9,00058
7zJTG 249 6,38793
7zK0Q 230 8,43970
7zetL 252 8,88544
D5GK 211 9,82171
D5a5 211 9,80907
he9 232 8,40205
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33488
7vAyp
 61 53,8% 221 8.225E-99
2 phalp2_34998
4MASs
 7 51,8% 158 1.722E-55
3 phalp2_714
1GW8q
 36 49,3% 152 1.133E-54
4 phalp2_15551
8jofz
 4 47,5% 141 2.574E-47
5 phalp2_6580
1dlN9
 3 45,3% 150 9.694E-42
6 phalp2_34371
4aKCB
 348 46,1% 143 1.287E-38
7 phalp2_25286
7YOmj
 5 41,1% 158 2.140E-37
8 phalp2_33807
1hNOs
 60 44,5% 155 3.997E-37
9 phalp2_18201
4IRhQ
 362 42,0% 145 6.317E-33
10 phalp2_627
1bpyM
 18 32,1% 171 3.363E-28

Domains

Domains [InterPro]
PET_M15
Unannotated
Representative sequence (used for alignment): aKO9 (234 AA)
Member sequence: A0A127AWA8 (313 AA)
1 234 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13539

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage SP-15
[NCBI] 		1792032 Thornevirus > Thornevirus SP15
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KT624200 [NCBI]
CDS location
range 71157 -> 72098
strand +
CDS
ATGGCAGCAGACATCAAGAATTTACACCCAGTAGTTAAAGAGAAAACCGAGCAACTTATTAGCATCATGGACAAGAAGCTAACTAAGTATAAAATGCGAATTACTCAGGGTTATCGTTCTATTGCTGAGCAGAATGAGATCTACGCACAAGGTAGAACTAAACCAGGTAGTATCGTTACTAATGCAAAAGGTGGTCAATCCTACCATAACTACGGACTAGCTATTGACTTCTGTCTGATTTCTCCTGATGGTAAGCAAGCCTCTTGGGATATGAACAAAGACTTCGATGGTGACGGAGTCGCTGACTGGAAAGAAGTTGTCACTGAAGCTAAGAAACTAGGTTTCGATTGGGGAGGAGATTGGAGTGGATTCAAAGACTATTCTCACTTTGAGATGACATTTGGATTGTCCATTAAAGACCTACAAAATGGTAAGCGTCCTGCTAATAGTGCGAAACCTAGTACTGGTGGCTCTAGTACTTCTACTTCTAGTAGTACTCTTAAATATGGCAGTAAGGGTTCAGCCGTAAAGACACTACAAAGTAATCTCAAGACTTTAGGCTACAACATTGGTAAGTCAGGTGTTGATGGTATCTATGGCAATGACACTGTAACTGCAGTTAAGAAATTCCAAAAGGATAAGAAATTAGCTGTAGATGGGATTGCTGGTTCTGCAACATTAGCTGCTATCAAGAAAGCTATTGATGCTAAGAAACCTAGTACTCCAGCTAGCAGTGGTAGTGCTATAGTTCCATATCCAGGTCATGTTATCAAATATGGTAGCAAAGGCAAAGATGTAGAACGTATCCAACGTGCAGTAAAAGTAAACCCTGATGGAATCTATGGTCGGGACACTGAAGCTGCAGTTAAAGCTTATCAGAAACGTCATGGATTGACAGCAGATGGTATCGTTGGTCTTAAGACTTGGAATGTAATGTTCTAA

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (aKO9) rather than this protein.
PDB ID
aKO9
Method AlphaFoldv2
Resolution 91.19
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50