Protein

Protein accession
A0A0K1Y8B3 [UniProt]
Representative
7zjVe
Source
UniProt (cluster: phalp2_6376)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSVNIISRAEWGAKPWNGTPNSVSLSKRTEFFVHYDGGHPVGRTGYDVPRAIERVHLNQGWSGVGYNFVVDQAGNIYEGRGWGLQGAHCPNHNVSGIGVQIAIGGDQEPSDKALAACRALYDEACRKTGRTLAKKGHKDGFATACPGPKLYAWVKAGMPAPKVEAPAPAPKPSTPAPKPSGDTYTVKRGDTLSGIGARLKIKWTDLAKANNLKAPYVIAIGQKLKLPAKAQPKSTIVALNKAVKPGATHAQVAELQQLLIKAGYGPIPGAVTRYYGKNTGAAVARFYRKNKHLASSSYDTAIGPKGFIELQREAGRK
Physico‐chemical
properties
protein length:317 AA
molecular weight:33801,0 Da
isoelectric point:9,93
hydropathy:-0,42
Representative Protein Details
Accession
7zjVe
Protein name
7zjVe
Sequence length
184 AA
Molecular weight
19344,40580 Da
Isoelectric point
9,50678
Sequence
VIDQAGTIFEGRGWNLQGAHCPGHNVSGLGVQIAIGGDQAPSDAALRSARALYDEACRRTGRTLAKKGHKDGIPTECPGPRLYSWVKAGMPVSGTDPDNGDSTPFPGRGAFVLSKTHPAVTVLGKRLVAHGFGRFYKEGPGPRFTEADRSATAAFQRAQGWSGSDADGYPGPTTWSRLMAPAGR
Other Proteins in cluster: phalp2_6376
Total (incl. this protein): 29 Avg length: 318,4 Avg pI: 9,47
Protein ID Length (AA) pI
7zjVe 184 9,50678
1cJeo 240 10,09512
A0A2P1JTQ5 358 9,56042
A0A0K1Y9C5 317 10,05044
A0A1B1PAB5 314 9,78973
K4I2E3 350 6,79331
A0A0K1Y9L3 323 9,91899
K4IB87 356 9,35502
A0A291AWH0 313 9,92602
K4NZK4 226 9,90977
A0A1J0MCP8 260 10,14180
A0A1J0MC10 260 10,14308
A0A411CPR5 358 9,60748
A0A7S6U320 357 9,59381
A0A0K1Y9U1 323 9,91899
A0A291AV60 317 9,92905
A0A291AW37 317 9,94736
A0A291LHM6 358 9,65609
A0A411CU36 317 9,94736
A0A411CVD6 317 9,94736
A0A5J6TJ01 358 9,65609
A0A5J6TR46 351 9,50298
A0A9E7MD70 350 6,79348
A0A9E7ME49 350 6,79348
A0A9E8M5B1 357 9,48725
A0AA51BQH1 353 9,46597
A0AAE8YFB9 277 9,76285
A0AAF0CK04 355 9,55726
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_15057
7s7pP
 172 49,7% 175 3.826E-49
2 phalp2_17750
7uiQL
 7 46,9% 162 7.582E-34
3 phalp2_20947
7lyTA
 33 40,0% 210 4.986E-33
4 phalp2_14767
6T7na
 9 32,9% 240 3.192E-26
5 phalp2_26274
RjMA
 376 35,0% 197 7.026E-22
6 phalp2_36432
11r0n
 207 30,1% 179 4.295E-18
7 phalp2_37752
4kTIO
 51 33,6% 187 5.859E-18
8 phalp2_14503
4QvOH
 19 29,4% 207 4.034E-13
9 phalp2_13951
8FOsh
 28 30,0% 183 4.726E-12
10 phalp2_13210
2JwXt
 44 25,4% 181 1.014E-10

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 7zjVe (184 AA)
Member sequence: A0A0K1Y8B3 (317 AA)
1 184 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Caliburn
[NCBI] 		1690425 Likavirus > Likavirus caliburn
Host Streptomyces griseus
[NCBI] 		1911 Actinobacteria > Actinobacteria > Streptomycetales > Streptomycetaceae > Streptomyces > Streptomyces griseus group

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KT152029 [NCBI]
CDS location
range 20958 -> 21911
strand +
CDS
TTGTCCGTGAACATCATCTCCCGCGCCGAGTGGGGGGCCAAGCCGTGGAACGGGACGCCGAACTCGGTGTCCCTGTCGAAGCGGACCGAGTTCTTCGTCCACTACGACGGCGGTCACCCGGTCGGACGGACCGGCTACGACGTGCCCCGAGCCATCGAGCGCGTCCACCTCAACCAGGGCTGGTCTGGCGTCGGCTACAACTTCGTGGTCGACCAGGCTGGCAACATCTACGAGGGTCGCGGCTGGGGCCTCCAGGGCGCTCACTGCCCGAACCACAACGTCTCTGGCATCGGCGTTCAGATCGCCATCGGTGGCGACCAGGAGCCGAGCGACAAGGCGCTGGCCGCGTGCCGTGCGCTGTACGACGAGGCGTGCCGGAAGACCGGCCGGACCCTGGCCAAGAAGGGCCACAAGGACGGCTTCGCGACCGCCTGCCCCGGCCCCAAGCTGTACGCCTGGGTGAAGGCCGGAATGCCCGCTCCGAAGGTCGAGGCTCCCGCCCCGGCCCCGAAGCCGTCGACTCCTGCCCCGAAGCCCTCGGGCGACACCTACACCGTCAAGCGGGGTGACACCCTCTCGGGGATCGGTGCTCGCCTGAAGATCAAGTGGACGGACCTGGCCAAGGCCAACAACCTGAAGGCCCCGTACGTCATCGCGATCGGTCAGAAGCTGAAGCTGCCCGCCAAGGCGCAGCCGAAGTCGACCATCGTCGCGCTGAACAAGGCGGTCAAGCCGGGTGCCACGCACGCGCAGGTCGCGGAGCTTCAGCAGCTCCTCATCAAGGCGGGCTACGGCCCGATCCCCGGTGCCGTCACTCGGTACTACGGCAAGAACACGGGAGCCGCAGTCGCGCGCTTCTACCGGAAGAACAAGCACCTCGCCTCCAGCTCGTACGACACGGCCATCGGGCCGAAGGGCTTCATCGAGCTTCAGCGCGAGGCAGGAAGGAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7zjVe) rather than this protein.
PDB ID
7zjVe
Method AlphaFoldv2
Resolution 89.86
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50