Protein

Protein accession
A0A4D6AP97 [UniProt]
Representative
7xThI
Source
UniProt (cluster: phalp2_35363)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVQVKTVTNDLLALANKGSGLDIDGVWGMQCVDLTNGVTTLYFGKSLWGNAIDLLDSAKSQGFNVIYEAVGVIPKEGWLFVMHAIADGVDYGHTGYIYKDSDGYTLDTIEQNIDGYSDNNLDGVNDQLQVGGSARINQRNFDNIVGYIVPDYEQIQEVVVTKNQEGDNDMFTISAEGRGIALIQGGTFFPILDAKDPIAFWNAGAKHIQVSTKTFDAFQGKKQASSLDDATVNKLIDGLRR
Physico‐chemical
properties
protein length:241 AA
molecular weight:26270,0 Da
isoelectric point:4,43
hydropathy:-0,18
Representative Protein Details
Accession
7xThI
Protein name
7xThI
Sequence length
385 AA
Molecular weight
42702,50110 Da
Isoelectric point
7,69005
Sequence
MVKVQEAINYIHSIVKNGGIDVDGYWGKQCVDLSNAVPQKFFNTRLEGNAIDLLNSAKKRGWVVEYDAVGVNPKAGAIFVSQEAMPYGHTGFVYEDSNGFTIKTVEQNIDGYSDKNNDGINDQLQVGGPARYHERTFDGVLGWFYPPYEDFKKGDKKMSKKILLIAGHGAGDPGAVSGGHTEEKITRELVKKMCIIDPTLDHYDYNRNCFADNGLARYALAEKYDEIVEFHLDSSGRGTATGGHTIIHSSFRPDNTDKAVQAVVNKYVGTFKGHAANGGFSFRNNLLNLNVAATVGYASYRLVELGFIDNATDRNKILNNLDKIANDFVLALRGEIKTELKPLKEVAREVRLGRWGNGKERVDRLTKAGYNAPEVQAEVDRQKKK
Other Proteins in cluster: phalp2_35363
Total (incl. this protein): 2 Avg length: 313,0 Avg pI: 6,06
Protein ID Length (AA) pI
7xThI 385 7,69005
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22245
7e47k
 317 32,6% 368 4.339E-32
2 phalp2_20990
7yFAa
 82 27,2% 283 3.179E-11

Domains

Domains [InterPro]
CHAP
Ami3
CW_7
Representative sequence (used for alignment): 7xThI (385 AA)
Member sequence: A0A4D6AP97 (241 AA)
1 385 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF05257, PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan629
[NCBI] 		2548288 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK448822 [NCBI]
CDS location
range 37394 -> 38119
strand +
CDS
ATGGTTCAAGTAAAAACAGTCACAAATGATTTGCTAGCACTTGCAAATAAAGGGTCAGGCCTCGATATTGACGGTGTTTGGGGGATGCAATGCGTCGATTTGACAAACGGTGTGACAACTCTATATTTCGGTAAATCATTATGGGGTAATGCTATCGATTTATTAGATAGTGCTAAATCTCAAGGCTTTAACGTGATTTATGAGGCTGTCGGAGTAATTCCAAAAGAGGGTTGGCTTTTTGTCATGCATGCTATCGCTGACGGTGTAGACTACGGTCACACTGGGTACATCTACAAGGATTCAGACGGGTACACATTAGACACGATCGAGCAAAATATCGATGGCTACTCAGATAATAATTTGGACGGTGTTAACGACCAATTACAAGTTGGTGGTTCTGCACGAATCAACCAACGTAATTTTGATAATATAGTCGGGTATATAGTGCCAGACTACGAACAAATACAGGAAGTAGTAGTAACAAAAAATCAAGAAGGAGACAACGACATGTTCACAATTTCGGCTGAAGGAAGAGGAATCGCTTTAATTCAAGGTGGGACATTCTTCCCAATTTTAGACGCAAAAGACCCAATCGCATTTTGGAATGCAGGGGCTAAGCACATTCAAGTATCGACAAAAACATTTGATGCGTTTCAAGGCAAAAAACAAGCATCATCATTAGATGATGCAACTGTCAATAAATTAATTGATGGCTTACGTAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000622050f_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7xThI) rather than this protein.
PDB ID
7xThI
Method AlphaFoldv2
Resolution 89.18
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50