Protein

Protein accession
A0A4D6ATD3 [UniProt]
Representative
1nLjj
Source
UniProt (cluster: phalp2_12594)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSIESSIAEMRCLAAIPVHYDMGDRYGNDADRDGRVEYDCSSAVSKAVGLSLNNNTETLKSNLPTIGYNCVYDGVDGSFDAQVGDVVIWGPRDMSSSLGAFGHVVIMTSPTTMIHCNYGYDGVTENDYNQIWEINGRPRETVYRLNAQAQAAPAPQPQASNRLKVYQVNDLQFVNGIWQVKCDDLCPVEFDWTQNGIACEDIDITDANGNVISDQETKVGSYFVINPDKVVSDGLGAYGSGGYYWRHVTLAASGQIWLSVWDVNHLLYG
Physico‐chemical
properties
protein length:269 AA
molecular weight:29577,5 Da
isoelectric point:4,38
hydropathy:-0,27
Representative Protein Details
Accession
1nLjj
Protein name
1nLjj
Sequence length
250 AA
Molecular weight
27676,21950 Da
Isoelectric point
4,56823
Sequence
MKSGINKGGLSMSKIESSIARMRHLQAIPVHYDMGDRYGNDDDGDGRIEFDCSSAVSYALEISLNNNTETLQQALPAIGYAKVFDAVDGSFDAQRGDVVIWAPRDGSSSLGAFGHVLIMTSDSTAIHCNYGMDGVTENDYNYIWDLNGRPREIVFRESGTPAPAPAQSAFDKELDVNARLEVSDKPYYEGTLTTDYYVEAGPRIDSQDKEFIAAGTRVRVYEKLNGWARINHPASSQWVEDKYLDDCTDM
Other Proteins in cluster: phalp2_12594
Total (incl. this protein): 56 Avg length: 242,4 Avg pI: 4,57
Protein ID Length (AA) pI
1nLjj 250 4,56823
1kJXA 241 4,63166
1meg4 239 4,51713
3lRkr 239 4,42778
5OzbR 229 4,44352
5QMV3 229 4,66542
5QhpZ 239 4,45256
5VkJU 229 4,49070
5VuzM 239 4,65673
5WMhC 239 4,55590
5XUTi 229 4,58346
5Z7QD 239 4,46393
61LK4 239 4,58460
62FBm 247 4,67327
67gpo 239 4,50252
6Ykgj 239 4,64121
6YoFj 239 4,52748
6c1pd 239 4,40783
6dcBU 239 4,38680
6fWl8 239 4,60768
6hLWC 272 4,57647
6q4L3 274 4,31081
6tirF 239 4,55590
6uiHF 239 4,40664
6vGhY 239 4,40783
73j26 241 4,94394
7C2df 241 4,76682
7NeM7 239 4,45256
7cRdl 237 4,60068
7eBS5 236 4,83287
7f6Pn 236 4,65923
7hIzK 236 4,59841
7ochL 239 4,70328
86iQQ 239 4,66923
88GoK 239 4,55590
8hjmG 239 4,40783
HJQH 239 4,45256
HwKo 235 4,59762
KQwG 247 4,62120
NoOe 239 4,54129
Ns07 239 4,57658
oMYC 239 4,73613
pOIo 239 4,54129
qIDB 239 4,44256
yoPt 250 4,70396
z701 239 4,64201
A0A4D6AWV2 271 4,39368
A0A4D6B667 241 4,94394
A0A4D6B1Y0 241 4,76682
A0A4D6AQ94 236 4,83287
A0A4D6AVE4 265 4,49678
A0A4D6AQP8 236 4,59841
A0A4D6AX23 265 4,51105
Q2I7P1 236 4,66747
A0A8S5SQS0 265 4,49678
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13886
7C1QD
 360 33,1% 193 9.027E-21
2 phalp2_20987
7y6FJ
 38 31,0% 222 5.648E-20
3 phalp2_9275
76k47
 345 35,5% 197 1.040E-19
4 phalp2_30831
8IEyq
 212 30,2% 185 2.997E-08

Domains

Domains [InterPro]
Ami5
Unannotated
Representative sequence (used for alignment): 1nLjj (250 AA)
Member sequence: A0A4D6ATD3 (269 AA)
1 250 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05382

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan110
[NCBI] 		2547981 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK448842 [NCBI]
CDS location
range 29969 -> 30778
strand +
CDS
ATGAGTATTGAATCTAGTATTGCAGAAATGCGGTGTTTAGCAGCTATCCCAGTCCATTACGATATGGGAGATCGTTACGGCAATGACGCAGACAGAGACGGACGAGTTGAGTATGATTGCTCTAGCGCGGTCAGTAAAGCGGTCGGATTGAGCCTTAATAACAACACAGAGACGCTGAAGAGCAATTTGCCTACAATTGGGTACAATTGCGTTTATGATGGCGTAGATGGCTCTTTTGACGCTCAGGTGGGTGATGTGGTTATTTGGGGACCTCGTGATATGTCTAGCTCGTTAGGTGCGTTTGGGCATGTTGTGATTATGACTAGTCCTACAACCATGATTCACTGTAACTACGGATATGATGGCGTGACCGAAAACGACTACAACCAAATCTGGGAAATCAACGGACGACCTCGTGAAACAGTCTACCGCTTGAATGCCCAAGCACAGGCTGCACCAGCTCCACAGCCACAAGCAAGCAATAGGTTAAAGGTTTATCAAGTCAACGATTTGCAGTTTGTCAATGGCATTTGGCAAGTCAAGTGCGATGACCTCTGTCCAGTAGAATTCGACTGGACACAAAACGGAATAGCTTGCGAGGATATTGACATCACAGACGCAAACGGCAATGTGATTAGCGACCAAGAGACAAAAGTAGGTAGCTACTTCGTCATCAATCCTGATAAGGTCGTGTCAGATGGCCTTGGAGCTTACGGCTCTGGTGGTTATTATTGGCGACACGTTACACTTGCAGCAAGCGGTCAAATCTGGCTGTCGGTTTGGGATGTCAATCATTTGCTTTATGGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1nLjj) rather than this protein.
PDB ID
1nLjj
Method AlphaFoldv2
Resolution 90.52
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50