Protein

Protein accession
R4JMG7 [UniProt]
Representative
5cNwZ
Source
UniProt (cluster: phalp2_16310)
Protein name
Peptidase M15A
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MQLTDHFTLEELTASDVARTRQIDNTPSAATVENLRRLAQTLEQARVLLGGKPMQITSGYRCPALNRAVGGVASSAHLAGLAADFVCPKFGAPLDVVRKLAASNLAFDQLIHEGGRWVHIGLAAAGVKPRRQVLTAHFSGETASYTVGA
Physico‐chemical
properties
protein length:149 AA
molecular weight:15803,9 Da
isoelectric point:9,18
hydropathy:0,02
Representative Protein Details
Accession
5cNwZ
Protein name
5cNwZ
Sequence length
212 AA
Molecular weight
22846,64720 Da
Isoelectric point
8,20671
Sequence
MTTRLSPNFTLEELCITQHRDIDNRPPTEVIKTLRETARRMEGVRAELDDRVITVTSGYRSPELNRRVGGARTSAHLKGYAVDFNCHGFGDPAQVCRALAAADLAFDQIIEEGSWCHISFDPRLRRQVLTRTRSGDYALGLLRAASRPAVVAAGAVALTGCASVGGTDAAATAKLLENLRGCERSYVGTLGGLAPPTASISIRCAPDEEPPR
Other Proteins in cluster: phalp2_16310
Total (incl. this protein): 30 Avg length: 157,1 Avg pI: 8,53
Protein ID Length (AA) pI
5cNwZ 212 8,20671
5ukcm 212 8,97285
C7BGD8 149 8,80072
A0A514CTN8 150 8,56548
A0A514CUV6 150 7,81113
A0A514CV07 150 8,56548
A0A5H2QAJ4 150 8,56548
A0A6H0X2X5 150 8,58398
A0A6G5Y8B3 150 8,56342
A0A6J5NSD5 152 7,84066
A0A6J5PQT6 144 6,57237
A0A6J5SJ07 147 9,09625
A0A6J7X5S4 161 6,51479
A0A889IRH0 139 6,82121
A0A9E7MPW6 153 9,49724
A0A9E7MRS4 153 9,49724
A0A9E7N1X3 155 9,89746
A0A9E7N6D7 153 9,17754
A0A9E7SLE8 155 9,63288
A0A9E7SN51 153 9,49724
A0A9E7ST13 153 9,49724
A0AA96KUQ5 150 8,58398
A0AA96KVE2 150 8,58398
A0AA96KVK9 150 8,58398
A0AA96KWI4 150 8,56548
A0AA96KWS2 150 8,58398
A0AA96R4V1 150 8,58398
A0AA96R7U4 150 8,56548
A0AAX4G1U8 222 6,42635
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37718
4e1ey
 787 48,2% 143 1.656E-48
2 phalp2_31042
1Db9K
 217 44,6% 150 3.107E-45
3 phalp2_30101
38zFk
 347 42,9% 156 1.085E-41
4 phalp2_33448
7cats
 1 40,6% 150 3.416E-40
5 phalp2_38153
6WaM5
 59 40,7% 184 4.673E-40
6 phalp2_8904
3b8fO
 2682 39,8% 138 2.748E-38
7 phalp2_8264
3Vy7
 8 43,2% 141 1.179E-36
8 phalp2_21836
4mpYp
 274 36,8% 163 1.289E-34
9 phalp2_1343
17yCd
 10947 40,1% 147 2.410E-34
10 phalp2_17441
7FS9W
 13 35,6% 143 1.404E-32

Domains

Domains [InterPro]
PET_M15
Disordered region
Representative sequence (used for alignment): 5cNwZ (212 AA)
Member sequence: R4JMG7 (149 AA)
1 212 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08291

Taxonomy

  Name Taxonomy ID Lineage
Phage Burkholderia phage ST79
[NCBI] 		1282994 Peduoviridae > Nampongvirus > Nampongvirus ST79
Host Burkholderia pseudomallei
[NCBI] 		28450 Proteobacteria > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > pseudomallei group

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KC462197 [NCBI]
CDS location
range 16643 -> 17092
strand +
CDS
ATGCAGTTGACGGACCATTTCACGCTGGAAGAACTGACCGCGAGCGACGTAGCGCGCACGCGGCAGATCGACAACACGCCGTCGGCCGCGACGGTCGAAAACCTGCGGCGTCTGGCGCAGACGTTGGAACAGGCTCGTGTGCTGCTCGGCGGCAAGCCGATGCAGATCACGTCGGGCTATCGTTGCCCGGCACTGAATCGCGCGGTGGGCGGCGTCGCCAGTAGCGCGCACCTTGCCGGGCTCGCGGCCGATTTCGTTTGCCCGAAGTTCGGCGCACCGCTCGACGTCGTGCGCAAGCTGGCGGCGTCGAATCTCGCGTTCGATCAGCTCATTCACGAAGGCGGCCGGTGGGTGCATATCGGCCTCGCTGCCGCCGGCGTGAAACCGCGTCGGCAGGTGCTGACCGCTCATTTCAGCGGCGAAACCGCGTCGTACACGGTGGGCGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
R4JMG7
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00032b68ea_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (5cNwZ) rather than this protein.
PDB ID
5cNwZ
Method AlphaFoldv2
Resolution 78.51
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50