Protein

Protein accession
G8EYD4 [UniProt]
Representative
8qK0c
Source
UniProt (cluster: phalp2_14068)
Protein name
Phage tail lysozyme domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MGNFRVSRAANLDYFMSVLTSDTITKMSGGRIPKMTKEQASGLVGSWIVETGNPKLENLDVIEKGAAAGRGLSQYTDGARPGRRTAYEIKRAEAVKKGVDPNSPQFQLRHFVDEYAGKLDRLVGGKSLIGWTRVFERAPKSGTPGQYAQYYTGSAASGKGYFRPSVPHTDKRMDAANQVFNIYKNVNLSQPGSTVFQPETTPRQFVQNILNLNPNTGANPWAMK
Physico‐chemical
properties
protein length:224 AA
molecular weight:24609,5 Da
isoelectric point:9,92
hydropathy:-0,59
Representative Protein Details
Accession
8qK0c
Protein name
8qK0c
Sequence length
204 AA
Molecular weight
22367,58680 Da
Isoelectric point
5,03425
Sequence
MEFVRNANTDYMMNVLTSPKIQEMSDGKIPPMSVAQASGLIGSWIVETGDPTLTNLDVIERDAGQGRGLSQYTGSRRIPYDIAASNAMQAGVDPNSAEFQLKYFAEEYAGKYDSNGRSLVGWTRIFERAPDGLSPNDYSKYYTGSAQSGKGYFRPSVPHLDKRSQYANAVFNAYNTDTPVGNPQLTVKPIDVPEPPVYNMGSAQ
Other Proteins in cluster: phalp2_14068
Total (incl. this protein): 83 Avg length: 208,7 Avg pI: 8,44
Protein ID Length (AA) pI
8qK0c 204 5,03425
15dqU 201 9,84672
19pYt 218 8,70673
1Abah 207 5,37921
1GIP 229 9,41672
1Gyna 223 9,63585
1NMcR 195 9,59717
1ULxX 202 6,19485
1UM0w 197 5,44099
1VCVH 193 6,74818
1VdAi 215 5,83807
1fGjL 215 8,95945
1rWNo 195 9,69277
1ugQH 217 9,98436
1wFbP 229 9,41646
28RLF 200 5,25098
2MJwl 213 5,11650
2MwEW 149 5,43366
2d0nP 234 9,11469
2hyCM 234 9,07878
2q29f 202 5,53961
2uffh 219 9,72107
2vR18 224 9,42149
2wjDz 221 9,24362
3YCGC 199 9,74486
3zCov 198 9,98359
46Xni 196 10,07094
48hRY 230 9,66421
4937A 198 4,62257
4A2dG 188 9,56919
4WCe5 223 6,45301
4XbIf 223 7,90049
4afLR 234 9,11469
4n7SJ 195 9,75041
4tvgn 262 8,75070
4uEhh 144 9,21751
4x56g 217 9,42149
4x57Z 219 9,75047
4zYki 265 9,74325
4zw9A 195 9,69277
59PSh 240 8,66231
5HjnK 200 9,58479
5dwT7 172 9,57028
5hqi7 254 9,77020
5ljiN 201 9,72107
5mybg 192 4,48081
5oj3c 198 4,50980
5taYM 208 9,54624
5us74 185 9,93582
5xi11 196 10,17268
6CYb7 219 9,66299
6ECU 202 5,52494
6GQCI 199 9,74951
6GdqU 201 9,77149
6KcP4 187 9,89263
6LBuw 234 9,72404
6LU88 201 9,87754
6LZmg 199 9,81791
6MDxv 184 9,94323
6VTAo 216 9,74609
6Y9TG 201 9,84621
6x8wj 199 9,74951
7IhUH 202 5,74951
7JQ96 198 4,59125
7JVvh 199 4,55538
7Kbxa 198 4,37879
7Qnnu 209 9,87870
7caEU 245 9,78870
836ic 224 9,37423
83S0t 207 5,39649
8AyKF 202 5,53961
8C0FW 224 9,37423
8CpSc 217 9,69019
8t2Vn 201 9,80031
La9x 197 9,81791
e1RR 219 9,69232
jJVC 187 9,89263
stly 185 9,88889
tiBP 240 8,64955
uvQE 150 5,02215
vNSu 224 9,63546
yOz0 262 9,04396
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_5127
1R6aU
 8 53,0% 183 7.058E-82
2 phalp2_4618
4llWk
 2 50,0% 178 4.921E-75
3 phalp2_37330
8p1Md
 7 42,8% 175 6.396E-49
4 phalp2_6943
2SsmN
 26 23,3% 167 1.180E-10
5 phalp2_17396
4LvTH
 16 22,9% 161 8.907E-08
6 phalp2_3650
7CO5Q
 3 23,9% 138 2.943E-07
7 phalp2_15086
757b
 5 26,8% 145 1.305E-06
8 phalp2_34726
38JC7
 5 26,9% 152 5.757E-06
9 phalp2_5269
8e5oF
 72 21,1% 170 1.041E-05
10 phalp2_12958
3aMd2
 55 21,4% 149 1.101E-04

Domains

Domains [InterPro]
Phage_lys2
Disordered region
Representative sequence (used for alignment): 8qK0c (204 AA)
Member sequence: G8EYD4 (224 AA)
1 204 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CBP42
[NCBI] 		461711 Autographiviridae > Aegirvirus > Aegirvirus SCBP42
Host Synechococcus sp. WH 7803
[NCBI] 		32051 Cyanobacteria > Oscillatoriophycideae > Chroococcales > Synechococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
JF974300 [NCBI]
CDS location
range 11115 -> 11789
strand +
CDS
ATGGGAAACTTCCGTGTTTCCAGGGCTGCAAACCTGGATTACTTTATGTCGGTTCTTACTTCCGACACAATTACAAAGATGTCCGGGGGACGAATCCCCAAGATGACTAAAGAACAGGCTTCTGGTCTGGTCGGCTCATGGATTGTCGAGACCGGGAATCCAAAGCTAGAGAACCTTGATGTGATCGAGAAGGGTGCAGCTGCTGGACGTGGATTGTCCCAATACACCGATGGTGCCCGCCCTGGTCGTCGTACAGCCTATGAGATCAAGCGGGCTGAAGCCGTCAAGAAAGGTGTAGACCCTAACTCCCCACAGTTCCAACTTCGTCACTTCGTTGATGAGTATGCGGGCAAGCTGGACAGGCTGGTGGGTGGTAAATCACTGATTGGCTGGACCCGTGTGTTTGAGCGGGCCCCAAAGTCTGGAACCCCCGGCCAATACGCCCAGTACTACACAGGTTCTGCTGCCTCAGGTAAGGGCTACTTCCGCCCCTCTGTGCCCCACACAGACAAGCGTATGGATGCTGCTAACCAGGTCTTCAACATCTACAAGAACGTAAACCTATCTCAGCCTGGCTCCACCGTGTTCCAGCCTGAAACTACACCCCGTCAGTTCGTACAGAACATCCTCAATCTAAATCCCAATACAGGAGCCAACCCGTGGGCTATGAAATAA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000235cc5e_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8qK0c) rather than this protein.
PDB ID
8qK0c
Method AlphaFoldv2
Resolution 86.34
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50