Protein

Protein accession
A7DYC6 [UniProt]
Representative
7Ns5Q
Source
UniProt (cluster: phalp2_19777)
Protein name
Putative endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MLKKTLAILGLSASLLFVSAHANAHTSRLTLDQTNELYTRLAAEGRGVDTDQVYGMQCVDIDTDLTNNYVGIPISGNAIDLLDSARRAGYEIVPANKPPRAGDLFVMDTNALYGHPFGHTGYVYKVNPDGSFETVEQNVGDDSNFYTGTVAKFMHRTRDYMLGYIRLAYRK
Physico‐chemical
properties
protein length:171 AA
molecular weight:18904,0 Da
isoelectric point:5,91
hydropathy:-0,26
Representative Protein Details
Accession
7Ns5Q
Protein name
7Ns5Q
Sequence length
264 AA
Molecular weight
28314,33200 Da
Isoelectric point
5,31043
Sequence
MATKSEVISWVCSLADRGIGVDADGAYGMQCVDLPNMVAQKFFGRSMWGNGIDMLSAGQGLGWHTTGGNVLPRAGAIFCMRVSYHGYGHTGIVVGEPDGNGNFQTVEQNVDGGLAGGPARYRVRSLGNPTENIIGFIYPPYSDGIDAPAGGQGGGPGGGGPTGYQGETMDFTFMISGDAGWNAQTIWYYNGAINEIQPLHNLEELKYLRAIYNDTHGGRDLKHYEWNTQAPVYVRIFGALKPSTEDNNIKAALNKIIKQLENAT
Other Proteins in cluster: phalp2_19777
Total (incl. this protein): 32 Avg length: 247,2 Avg pI: 5,90
Protein ID Length (AA) pI
7Ns5Q 264 5,31043
5OD5W 249 5,96283
5QikZ 246 6,15370
5Xqpi 216 6,36349
64I1J 211 6,19820
64I4y 259 5,58832
64lFT 265 5,39347
667q3 261 5,47993
6Z2Vk 259 5,64533
6rpbR 259 5,65454
6wHGB 249 6,15699
708nt 259 5,64533
70Rtl 259 5,64533
7MSrO 259 6,20928
7N30c 246 5,96851
7Na1v 252 6,65217
7OoQW 245 6,15773
7Oxjw 259 5,64533
7P1Ah 259 5,64533
7UMFC 259 5,65454
BLmT 252 6,59039
CmpS 259 5,65454
F4LZ 259 5,41729
HMWd 265 5,31043
HuA7 246 6,15767
Nfrt 246 5,96851
oBwb 259 5,42883
p51t 246 6,05235
pNFR 252 6,58795
wGfU 250 6,58795
A0A0K0MWL2 171 6,04945
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_26044
71X3w
 16 32,2% 273 2.168E-34
2 phalp2_3976
7uafd
 2 27,3% 252 7.555E-11

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): 7Ns5Q (264 AA)
Member sequence: A7DYC6 (171 AA)
1 264 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage M102
[NCBI] 		372457 Aliceevansviridae >
Host Streptococcus mutans
[NCBI] 		1309 Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
AM749121 [NCBI]
CDS location
range 20879 -> 21394
strand +
CDS
ATGCTCAAAAAAACATTAGCAATTTTAGGTTTGTCAGCTAGTTTATTGTTTGTATCGGCACACGCGAACGCGCATACATCAAGACTAACATTAGACCAGACAAACGAACTTTACACACGTTTAGCCGCGGAAGGTCGTGGTGTGGATACTGACCAAGTTTATGGCATGCAATGTGTGGATATTGATACAGACTTAACTAATAATTATGTAGGCATTCCGATTAGTGGAAACGCTATTGACCTACTAGACAGCGCACGACGTGCAGGCTATGAGATTGTGCCAGCTAATAAACCGCCTCGCGCTGGAGATTTGTTTGTTATGGATACTAACGCGCTTTACGGCCACCCTTTCGGTCACACTGGCTATGTTTACAAGGTTAATCCTGATGGCAGTTTTGAGACTGTAGAACAAAATGTAGGTGATGACAGCAATTTTTACACTGGCACAGTAGCTAAATTTATGCACCGCACACGCGATTACATGTTAGGTTATATACGCTTAGCATATCGCAAATAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A247D730
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A7DYC6
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00015968f8_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7Ns5Q) rather than this protein.
PDB ID
7Ns5Q
Method AlphaFoldv2
Resolution 84.42
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50