Protein

Protein accession
E5DQQ0 [UniProt]
Representative
2n3Y4
Source
UniProt (cluster: phalp2_1719)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MLAQMLKQDEGYKETVYWDTEGYPTIGIGHLILKKKTRDMGEINRELSSHVGRIVNDGKISGAEVLALFERDLAAIQRTMMAVPALASVYVELDAVRKTAIENMVFQMGAIGVSKFPGMLRALKAKDWNMAYKQALDSSWAKQTPNRANRVASVLKLGSYAPYEF
Physico‐chemical
properties
protein length:165 AA
molecular weight:18417,2 Da
isoelectric point:9,25
hydropathy:-0,18
Representative Protein Details
Accession
2n3Y4
Protein name
2n3Y4
Sequence length
342 AA
Molecular weight
36963,31660 Da
Isoelectric point
4,84748
Sequence
RITEEECSMLFERDLSSVYSSISSNSKVGPVYSMLDDTRKMAIINMTFQMGVGGVANFNTMLGYLALGQYDNAADAALDSLWARQTPSRARRVSEVIRNGNLVPYGGSQGSAPSLQTMRMFKTASVSSAAQAPSFTEPESPYSAVYPYNKVYESESGHIQEFDDTPGHERIKTYHRTGTFEEIHPDGTKVTKIIGDDFYIVKNDGNVHIGGKLKIVVDGDADIFVQGDSNSTISGNATQFVRGNVDERVEGNVNQYVTGNSTALVKGNLNADVEGNADIKVMGDCFNTIDGNYTLKIGGNFSTEVGGSRTDDVSGNWNRQSAQVSDVAQGTFSIDGSRINLG
Other Proteins in cluster: phalp2_1719
Total (incl. this protein): 45 Avg length: 413,9 Avg pI: 6,99
Protein ID Length (AA) pI
2n3Y4 342 4,84748
A0A223LE97 166 9,46578
A0A898KAB9 583 4,99520
A0A482GQP9 402 5,44202
I6X7Z7 166 9,49144
E1A2L4 165 9,54785
J7I148 583 5,00043
J7KEV5 583 4,95786
A0A291LDA0 166 9,49144
Q76YA6 165 9,39557
A0A219YAQ4 600 5,50153
A0A2S1PEJ3 583 4,99520
A0A2H4YFB5 165 9,29874
A0A219YC19 166 9,46610
A0A219Y9H1 600 5,48305
A0A219YDC2 600 5,48305
A0A219YEK1 600 5,55882
A0A240F3A7 600 5,55882
A0A411B871 166 9,46578
A0A411BAB0 165 9,39557
A0A411BD81 165 9,39557
A0A411BIC4 166 9,41846
A0A4D6BGC4 602 5,67585
A0A514A724 586 4,96968
A0A7S5SL82 165 9,51813
A0A7T5QYI1 166 9,41846
I6ZRF8 583 4,95786
Q19CN7 557 4,93433
Q6U9G4 600 5,48305
A0AA94YER8 613 5,66784
A0AA94YJB6 583 4,95257
A0AA94YNB2 613 5,66784
A0AA94YP60 600 5,50153
A0AA94YPR6 613 5,66784
A0AA94YQV2 583 4,99520
A0AA94YRH1 613 5,66784
A0AA94YT60 613 5,66784
A0AA95C3H3 600 5,50153
A0AA95C453 600 5,50153
A0AA95C4P3 613 5,66784
A0AA48QZJ5 165 9,54785
A0AA95C6T2 166 9,57106
A0AA95C786 165 9,43052
A0AB39TZF0 166 9,46578
Similar Clusters

No similar clusters were found for representative 2n3Y4.

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Aeromonas phage PX29
[NCBI] 		926067 Straboviridae > Angelvirus > Angelvirus px29
Host Aeromonas salmonicida
[NCBI] 		645 Proteobacteria > Gammaproteobacteria > Aeromonadales > Aeromonadaceae > Aeromonas >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
GU396103 [NCBI]
CDS location
range 214692 -> 215189
strand +
CDS
ATGCTTGCACAAATGTTAAAACAGGATGAGGGATATAAAGAAACGGTATATTGGGACACAGAAGGATATCCAACTATCGGTATCGGACACCTTATTCTGAAAAAGAAAACTAGAGATATGGGAGAAATCAATCGCGAATTGAGTTCCCATGTTGGTAGAATCGTAAATGACGGGAAGATCAGCGGAGCGGAAGTGCTTGCGTTGTTCGAACGTGACTTAGCAGCGATACAGCGCACCATGATGGCTGTGCCTGCTTTGGCCAGCGTTTACGTCGAACTTGATGCAGTGCGTAAGACTGCTATCGAAAACATGGTATTTCAAATGGGAGCCATCGGTGTGTCTAAGTTCCCGGGTATGCTTCGCGCACTGAAAGCGAAAGACTGGAACATGGCATATAAGCAAGCTCTTGATAGCTCATGGGCAAAGCAGACACCAAACCGCGCCAATCGCGTTGCCAGCGTTTTGAAACTGGGGTCTTATGCTCCATATGAATTTTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
upi0001f1f8cd_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (2n3Y4) rather than this protein.
PDB ID
2n3Y4
Method AlphaFoldv2
Resolution 89.16
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50