Protein

Protein accession
E9NIF0 [UniProt]
Representative
2Vze6
Source
UniProt (cluster: phalp2_27135)
Protein name
Peptidase C51 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MITYPWLEQAKKLEGIHEATKAGSEAVDQLWRDFKMSGNVGKSTSLPWCSALIGGCMERSGISTRLPEGTKNPISKDSSQYWTQWGTKLDKPVVGAIVVFRWSPNAGHVGFVVGKTANGLLLVLGGNQSDSVCVKAFKTDRIVGYYFPRNQEIKSYDLPIGTAAEMSASQTR
Physico‐chemical
properties
protein length:172 AA
molecular weight:18802,3 Da
isoelectric point:9,15
hydropathy:-0,28
Representative Protein Details
Accession
2Vze6
Protein name
2Vze6
Sequence length
259 AA
Molecular weight
28321,01870 Da
Isoelectric point
6,17490
Sequence
MTLSPEPEWMAEARSYIGEREIKGRQHNPLILRWWTLIHAGFSDDETPWCAAFVGGILENHGIKSSRSAAARSYLTWGRVLDRPIPGCIAVLERGPRNGHVGFVTGITRDGRIVLIGGNQGDEVSEAPFEMGRVLGWRWPESVPVPMFASLPTVDPNLPTSRRESFYGADDIMGDEGEGKHPADFPVLELPAPAESSTTTRFKHITNFLATGAATGLASLLAAFNRIPVEVVIAICATGLIVFAIIWFTSMRRGCHSGR
Other Proteins in cluster: phalp2_27135
Total (incl. this protein): 4 Avg length: 227,5 Avg pI: 6,32
Protein ID Length (AA) pI
2Vze6 259 6,17490
A0A1E1GDL9 243 4,72584
A0A976XGC3 236 5,20971
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_38714
WdJZ
 70 47,8% 165 1.953E-42
2 phalp2_8523
1pCMB
 7 43,3% 166 1.355E-34
3 phalp2_9646
1LfXa
 7 37,3% 166 8.246E-29
4 phalp2_27707
6Pypi
 4 27,3% 172 3.359E-13
5 phalp2_29792
1Qqqg
 22 29,0% 165 8.011E-08
6 phalp2_39928
1open
 1 25,3% 197 6.109E-04

Domains

Domains [InterPro]
CHAP
Disordered region
Representative sequence (used for alignment): 2Vze6 (259 AA)
Member sequence: E9NIF0 (172 AA)
1 259 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Enterobacter phage EcP1
[NCBI] 		942016 Schitoviridae > Eceepunavirus > Eceepunavirus EcP1
Host Enterobacter cloacae
[NCBI] 		550 Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Enterobacter > Enterobacter cloacae complex

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HQ641380 [NCBI]
CDS location
range 8453 -> 8971
strand +
CDS
ATGATTACATATCCATGGCTTGAACAAGCTAAGAAATTAGAAGGTATTCACGAAGCTACCAAGGCAGGCTCAGAGGCTGTAGATCAGCTTTGGAGAGACTTTAAAATGTCTGGTAACGTTGGTAAGTCTACCTCCCTTCCGTGGTGTTCTGCGTTGATTGGTGGCTGTATGGAGCGATCTGGCATATCTACCAGACTTCCTGAAGGTACTAAAAATCCAATTTCAAAAGATAGCTCACAATACTGGACTCAATGGGGAACCAAATTGGATAAACCAGTTGTAGGGGCTATCGTAGTATTCCGTTGGAGTCCTAATGCAGGTCACGTTGGATTCGTAGTAGGTAAAACTGCAAATGGTTTACTGTTAGTTTTAGGTGGTAATCAGAGCGATTCTGTATGTGTAAAAGCATTTAAAACAGATCGGATTGTTGGTTACTACTTCCCACGGAACCAAGAAATAAAATCTTATGACTTACCGATTGGCACTGCGGCTGAAATGAGCGCAAGCCAAACAAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001f73f0f_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (2Vze6) rather than this protein.
PDB ID
2Vze6
Method AlphaFoldv2
Resolution 75.32
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50