Protein

Protein accession
A0A2P1CDJ4 [UniProt]
Representative
7gJ1L
Source
UniProt (cluster: phalp2_29143)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPAVLGQLTLDSSYDDVANAIVQESFRRGHQRVEAVAELATGIQESSLRPRAVSANGKWKGVYQQDTSYPGRDNANEQIREFMNRLDVKRRSPNHGDIWGNIFWLQQRPGEPSAAAAYANGRKAYMTEIKSRTAEAERLVAKYWPADNPSTPTPGGTAPVVARPDFNEINEIDGTHASPRSRPPINFFLHTQEGNGNAQTLAAYLRSTSGAGAVSYHYTVHEDPNDHGVTVVDVVDTDYYSWSVLDANVFSINLCFAGSYAAWTREQWLSKASRAIDVAAYLAVEDCKKYPTIAADVILPPYTNRPGISDHRYVTKCLGIGSHTDVGGPMQAPWTGFPWDVFQAAVNKYAGVPVGAPEPAQPTFEQWLAKASEADLLRYVAEQLGPGHPAWESKGMTLRDKLWSLGT
Physico‐chemical
properties
protein length:407 AA
molecular weight:44740,3 Da
isoelectric point:5,83
hydropathy:-0,46
Representative Protein Details
Accession
7gJ1L
Protein name
7gJ1L
Sequence length
1575 AA
Molecular weight
160414,67990 Da
Isoelectric point
5,67074
Sequence
MTAPGGAWASAHVDVELDWGNLDEELIRRLERSAQIAQRAVNKHLDKIATNAERTFDKVERGFDSQMRAMERRSDVAARQVNKNLGKIRDRDITLNVDVDDTQAVGQVRGAHRAMQAWASANPIEFGVSVDHRGARSALGGILGTLQRETSRRQVKVDIDVDRRGLGRAALGSIGSMLGTVGGKALTGAKFLGKWAGILGSATIAAGSLVPVIGALGSGLVAIGGAAGTVAVGGLFALGAAGAAVMVAFNGMGDAIKSALDPEASPEDFAKAIEGLSPAAQSVARSVRGLGQAWEEAGVKAAVQEAMFAGLGPKIAGLGRLIVPLRESLRTVAEGFNDGANGALRMINSASGMSMVKSLLADAGNMGANLGAAVTASIPGFLSLGSAASSVISPLTDGIGAMAQRWSESMLRMQQDGTLQAKMQGLLDTARQVGAALMKVGEIVGGVFRAAAAAGNGNPLGNIMGTLTAVSDWVNGPGQAALTSFFTSVGQVTSTLAPILLQVAGIIGGQVAPMIAQLVTTIGPVVGEIVTQLGYGVAALQPAIAPLGAALSQIGAALAPVLPILGQLIAQFVQLAGPILGALAQALSPILQAVGQALIAAFQALMPAIAPISNLFATLAPIIAQIATVLGQVLASAITALMPLFQTWLDVVSQLFAALSPIIPVIGEALVSAISAVAPFIEQLATMLGDALGAAIQTIAPLIPQIASAFMQILDAVMPLVPILLQLVLTCLQPIIGLLPTLMSVIASLVPVLVQLASMFASLVSAVMPVVAIIAKVIGFFVQLLGTIINFAAQALATILGWVAGIIAGFLNMVTTVVSTVSGWVGNILGFFGDLVSRAISFVTDMWQRVTTGFSEGVSKAVDFVKELPGKIMGAFADAGKWLWDAGKKIIGGLIDGIKSMLSSLGNAIVSIFPSIIQGPVRRVLGLALGGLVPGLAAGGILDALGGGEVTGATTTIRPGGFIVNAAATRKNKALLKQLSPRGRVLSGPGTGTSDSITGRYNGRAVARVSKGEWYAPPQDAAQILPLLMAVNAGKKTVALARAAGGLLPAFAPGGMIPTELRDRARQAVQSGYVWGGWGNGWNTDCSGLTSSLANMATGRASGPGEGERTATGGMRAFLEARNFQDGAIPGALQVGWSDTHSAATLPTGENIEHTGPEGAPASFGADAKGADSLPNVMSLPMGGDTDSGALGGGLTPGSTGGGGGSTPIGSGIGSGPGGGASWGNSGGSSKANSAADAERIGLTPVWVENWPAQIGGGGGTGGLSVGDTTPNAGVAPAATPPAPKLTASSSKKDVAAAIYAKARDRGYSHEEALAIVSTAIQESNLDANASGGGGAWHGYFQQDESYPDRDDPEGNVNGFLDRLDEKTKADPNSDIWKRIFWLQQRPGESSAEAAYGNGRQAYLSEIQSRQGEAKDLVGQVPVTPQGTVPVTVTDDQTTAPQTPPPATTTPPADAGLSPGGTPAADKPLSESMPYGKARADQYLREQNLGPALQDIGVAGLKETFGEFGDLIGVKPYVEQGIDQAVAYLKQIAERKPAPSTVKLADTVNNYGDPQETKQKTTAGMTAVMDTYRGD
Other Proteins in cluster: phalp2_29143
Total (incl. this protein): 140 Avg length: 1323,8 Avg pI: 8,06
Protein ID Length (AA) pI
7gJ1L 1575 5,67074
6RsP4 1653 4,83696
72ufj 1650 9,28501
7AFG1 1604 9,33568
7AFHm 1677 9,32202
7AFLb 1838 7,00281
7AFOm 1607 9,34232
7AFVc 1899 6,72430
7AG2q 1844 6,98070
7AGNW 1837 6,95569
7AGjO 1608 9,30351
7AGr2 1838 6,67065
7AGyl 1837 6,51741
7AH0R 1607 9,34226
7AH3G 1608 9,29049
7Ad4z 1607 9,33568
7AoLN 1653 9,17200
7AuLD 1672 9,30274
7AuN0 1672 9,42568
7AuR4 1714 8,88995
7AuVf 1671 9,39931
7AuXX 1705 8,97640
7Av0w 1690 9,27676
7Av4X 1629 9,20023
7Ax6j 1671 9,33484
7AxdF 1672 9,37810
7PJQ3 1596 6,04343
7PKrh 1706 8,97640
7PL3q 1603 9,28404
7jHfr 1843 6,80052
7ssKW 1543 9,36411
7wDYX 2000 8,99916
7zSHS 1603 9,34232
8LBP5 1608 9,30351
8LCLg 1607 9,32898
8LCUX 1604 9,30351
8LChA 1607 9,30351
8LCiU 1607 9,32898
8LCki 1608 9,32898
8LyFq 1636 9,18612
8LyGQ 1637 9,22377
8LyL0 1630 9,28437
8LyMt 1642 9,39242
8LyQz 1708 9,03584
8MDbY 1672 9,37133
8MEKJ 1670 9,40608
8MEM8 1671 9,34155
8MENp 1607 9,34232
8MI4a 1840 6,64518
8MIEk 1832 6,75051
8MJsY 1607 9,30351
8MNYk 1652 9,29784
8MQ3N 1609 9,34232
8MQ5f 1607 9,34232
A0A3G3M7T7 1604 9,33568
A0A385DW79 1677 9,32202
A0A7G3V9C5 1607 9,34232
A0A5P8D5Y2 1608 9,30351
A0A3G3MAI0 1607 9,34226
A0A3G3MAV5 1608 9,29049
A0A2L0HJK9 1607 9,33568
A0A7G8LL82 1672 9,30274
A0A7G8LM82 1672 9,42568
A0A3G3M8B1 1671 9,39931
A0A411CSF1 1705 8,97640
A0A7T1NW92 1690 9,27676
A0A515MKY7 1671 9,33484
A0A345KPE4 1672 9,37810
A0A0K0MWQ5 1706 8,97640
A0A142K9T4 1603 9,28404
A0A2U9PFK9 1603 9,34232
G8IBT3 442 6,08481
Q19YV7 407 6,07929
A0A345KUA8 1608 9,30351
A0A4Y6EN53 1607 9,32898
A0A5P8D4R8 1604 9,30351
A0A3G3M824 1607 9,30351
A0A3G3M8A6 1607 9,32898
A0A3G3MAB9 1608 9,32898
A0A7T1KS76 1708 9,03584
V5RBJ8 445 5,95828
A0A385DTY0 1672 9,37133
A0A3G3M8J9 1670 9,40608
A0A3G3M924 1671 9,34155
A0A3G3M9H1 1607 9,34232
A0A514DEL8 1607 9,30351
A0A7G8LKI4 1609 9,34232
A0A7G8LDW6 1607 9,34232
A0A0B5A693 421 5,61623
A0A0F6YQY4 425 5,51670
A0A0F7DDA4 421 5,51670
A0A2L0HLE9 421 5,51670
A0A2P1CCT6 407 5,83295
A0A2R3ZYX7 421 5,51670
A0A345KYC7 400 5,83295
A0A345MCN5 421 5,51670
A0A3G3M8N6 1677 9,32853
A0A411CIB9 421 5,51670
A0A4Y6ELM0 1708 9,03584
A0A514DGD7 1604 9,28404
A0A514TY07 407 5,83295
A0A5J6TV94 425 5,51670
A0A5Q2WCB2 407 5,83295
A0A5Q2WDW6 421 5,51670
A0A6M3T272 425 5,51670
A0A6M3TBZ9 425 5,51670
A0A7L8ZDT5 1705 8,98240
A0A7L8ZEJ2 407 5,83295
A0A8F3E2X1 1705 8,97640
A0A8T8JF89 1604 9,30351
B5A6F3 355 6,00029
B9W1G8 421 5,51670
G1BLK3 421 5,51670
G8I3S7 425 5,51670
G8I770 425 5,51670
G8I812 421 5,51670
X2KS06 421 5,51670
X2KYM3 407 5,83295
A0A2P1CH67 407 5,83295
A0A2Z4Q1Q2 407 5,83295
A0A3G8FGB5 407 5,83295
A0A514TYA3 407 5,83295
A0A8T8JCM0 425 5,51670
A0A976U824 1608 9,29049
A0A9E7J371 1676 9,29636
A0A9E7S0I1 1671 9,38500
A0A9E7SY30 1672 9,39931
A0A9E7U3C9 1678 9,28991
A0A9X9K3V7 1605 9,26232
A0A9X9P5H1 425 5,42928
A0AA51BP58 1672 9,37133
A0AA96K0K7 407 5,83295
A0AA96KMM2 1709 8,62124
A0AA97A0G6 1608 9,34232
A0AAE7SED2 1604 9,34232
A0AAE8X9C4 1671 9,34825
A0AAE8Y487 407 5,83295
A0AAF0GL81 407 5,83295
A0AAF0GNI1 421 5,51670
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20938
7fSA6
 1 23,9% 1623 1.077E-73
2 phalp2_10362
1FB4z
 1 20,6% 1165 2.628E-53
3 phalp2_3853
6GEo4
 2 19,2% 1191 7.083E-38

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage ChaChing
[NCBI] 		2099629 Pipefishvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG925338 [NCBI]
CDS location
range 40324 -> 41547
strand +
CDS
ATGCCCGCAGTCCTCGGACAATTGACGCTCGATTCCAGTTACGACGACGTGGCGAACGCGATCGTGCAGGAGTCATTCCGGCGCGGGCACCAGCGCGTCGAGGCGGTGGCCGAACTCGCGACCGGGATCCAGGAGTCGTCACTGCGTCCGCGCGCCGTGTCGGCGAACGGGAAGTGGAAGGGCGTCTACCAGCAGGACACCAGCTATCCCGGCCGCGACAACGCGAACGAGCAGATCCGCGAGTTCATGAACCGGCTCGACGTGAAGCGCCGCTCGCCGAACCACGGCGACATCTGGGGAAACATCTTCTGGCTCCAGCAGCGACCGGGGGAGCCTTCGGCGGCTGCGGCGTACGCGAACGGCCGGAAGGCCTACATGACCGAGATCAAGTCGAGGACCGCCGAGGCGGAGCGACTGGTCGCGAAATACTGGCCCGCCGACAACCCTTCGACCCCGACACCAGGAGGCACAGCGCCCGTGGTCGCACGACCGGACTTCAACGAGATCAACGAGATCGACGGCACCCACGCGTCACCGCGCAGCCGTCCTCCGATCAACTTCTTCCTGCACACCCAGGAGGGGAACGGGAACGCTCAGACCCTCGCGGCGTACCTGCGGAGCACGTCCGGCGCTGGAGCGGTGAGCTACCACTACACGGTCCACGAAGACCCGAATGATCACGGCGTGACCGTGGTGGACGTGGTCGACACCGACTACTACTCCTGGTCCGTGCTGGACGCGAACGTCTTCTCGATCAACCTCTGCTTCGCCGGGTCGTACGCAGCATGGACGCGGGAGCAGTGGCTCTCGAAGGCCAGCCGCGCGATCGACGTGGCGGCGTACCTGGCCGTCGAGGACTGCAAAAAGTACCCGACGATCGCCGCTGACGTGATCCTCCCTCCGTACACGAACCGGCCGGGGATCTCCGACCACCGGTACGTGACGAAGTGCCTCGGGATCGGCAGCCACACGGACGTGGGCGGACCTATGCAGGCACCGTGGACTGGGTTCCCGTGGGACGTGTTCCAGGCGGCGGTGAACAAGTACGCGGGTGTCCCCGTCGGCGCACCGGAACCGGCACAGCCCACGTTCGAGCAGTGGCTCGCGAAGGCCTCCGAAGCCGACCTCCTGCGGTACGTCGCCGAGCAGCTCGGGCCGGGACATCCGGCGTGGGAGTCGAAGGGCATGACGCTCCGCGACAAACTCTGGAGTCTGGGGACGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7gJ1L) rather than this protein.
PDB ID
7gJ1L
Method AlphaFoldv2
Resolution 50.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50