Protein

Protein accession
A8ATR6 [UniProt]
Representative
41cMd
Source
UniProt (cluster: phalp2_29857)
Protein name
PlyP35
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MARKFTKAELVAKAEKKVGGLKPDVKKAVLSAVKEAYDRYGIGIIVSQGYRSIAEQNGLYAQGRTKPGNIVTNAKGGQSNHNFGVAVDFAIDLIDDGKIDSWQPSATIVNMMKRRGFKWGGDWKSFTDLPHFEACDWYRGERKYKVDTSEWKKKENINIVIKDVGYFQDKPQFLNSKSVRQWKHGTKVKLTKHNSHWYTGVVKDGNKSVRGYIYHSMAKVTSKNSDGSVNATINAHAFCWDNKKLNGGDFINLKRGFKGITHPASDGFYPLYFASRKKTFYIPRYMFDIKK
Physico‐chemical
properties
protein length:291 AA
molecular weight:33057,4 Da
isoelectric point:9,86
hydropathy:-0,66
Representative Protein Details
Accession
41cMd
Protein name
41cMd
Sequence length
226 AA
Molecular weight
24983,31020 Da
Isoelectric point
9,87593
Sequence
MDMKKLHPRLRKLTNELVTACERKGIPIKITQGYRSKAEQDALYAKGRTKPGNRVTNARGGYSMHNWGIAIDFCRADGKGAYDDSDGFFSKVGKVGKSLGLEWGGDWKSIKDKPHFQLPDWGSTTEKLRTKYGTYEKFVKTWGDSKPVTNKTTTSVKRAEDVSMTTIKKGSKGKAVKIWQVIVGTTVDGSFGDSTVAKTKAFQKKHKLTADGVVGDKTWKAGLESI
Other Proteins in cluster: phalp2_29857
Total (incl. this protein): 95 Avg length: 257,0 Avg pI: 9,39
Protein ID Length (AA) pI
41cMd 226 9,87593
11AZx 254 9,74048
11BYz 263 9,84730
13Exk 265 9,55520
1abMl 227 9,53560
1bXeM 228 9,61419
1cBu7 254 9,84634
1cuLW 253 9,76936
1mHna 306 9,54591
1n8VY 252 9,84395
29vI8 249 9,73255
2UW36 307 9,59678
2b9fj 276 9,22261
2ejqn 259 9,06627
36F8J 312 8,68068
3Lm8j 237 9,45134
3LvTY 256 9,49382
3MAGu 227 9,47551
3MSHO 307 9,71076
3VD7T 222 9,65822
3sPSM 253 9,71160
3vHkI 253 9,71695
3zDWO 239 9,58079
4DCmM 237 9,62057
4Emoq 227 9,56461
4VYos 252 9,57306
4eRnV 233 8,96015
4y87A 251 9,37275
4yiyB 234 9,68098
5MKek 253 9,67782
5PLxK 293 9,37088
5Ui9J 252 9,90088
5XgJT 254 9,71540
5hQ6o 231 10,00467
5hSA7 231 9,83344
5hVry 224 8,93488
5hX8A 288 10,03691
5i3IV 228 9,15233
5imRx 231 9,91029
5ipPl 231 9,93930
5u1Wo 230 9,77684
64UCY 253 9,63759
69qSr 301 8,92618
69ruw 256 9,72301
6F2oh 223 9,10927
6F3Xx 242 9,27495
6TflL 237 9,48757
6a92f 254 9,72733
6cUQy 252 9,77865
6dVGO 253 9,71695
6gO0X 252 9,80069
6lfUW 252 9,70412
6lrCL 252 9,81462
6rhIb 252 9,75505
6tMOS 252 9,78309
6tMSc 252 9,84369
6uYMm 252 9,81462
6vGMU 252 9,82139
6vgza 215 6,35911
6wEbo 261 9,77039
6wPv3 253 9,59975
75TSZ 306 9,48048
76riS 280 9,31241
76riV 227 9,41027
79394 317 9,53192
7LSuF 262 9,20810
7Pn6R 262 9,20810
7Pnyl 243 9,37759
7b2IE 262 8,92431
7c1lr 213 9,79760
7dBZ1 306 9,62379
7dKHM 243 9,87818
7hj5U 279 9,73751
7jxTr 313 9,57415
7ofD2 267 9,23157
7ofEP 273 9,21906
7qcfu 213 9,91074
7rWRl 309 9,36605
7rWSh 309 9,37604
7zeEv 230 9,82358
86wSj 216 9,64139
87Qyg 218 9,09651
8HmoL 262 8,92431
8L72w 243 9,36147
8L9Dy 251 9,68923
8LaMf 243 9,21655
8Ml5c 313 7,67459
8chFB 289 9,72178
8nf7D 216 9,67118
8oRV4 253 9,68497
bJlK 305 5,52682
e6GH 280 5,74633
e6s9 305 5,78458
A0A059T5J4 291 9,88876
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2874
ol4j
 82 63,6% 143 5.795E-67
2 phalp2_8235
7vUi0
 89 38,8% 224 1.489E-66
3 phalp2_22764
8sBEP
 4 45,0% 231 3.553E-56
4 phalp2_714
1GW8q
 36 46,0% 139 1.542E-51
5 phalp2_12448
qevc
 108 56,2% 144 3.956E-51
6 phalp2_35414
f7cN
 32 49,2% 140 2.562E-44
7 phalp2_33807
1hNOs
 60 38,5% 153 9.856E-42
8 phalp2_8374
t0k3
 1 36,0% 219 1.206E-40
9 phalp2_34998
4MASs
 7 34,3% 195 1.802E-38
10 phalp2_8189
7bcYD
 17 29,2% 229 1.434E-36

Domains

Domains [InterPro]
PET_M15
PG_1
Representative sequence (used for alignment): 41cMd (226 AA)
Member sequence: A8ATR6 (291 AA)
1 226 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF13539

Taxonomy

  Name Taxonomy ID Lineage
Phage Listeria phage P35
[NCBI] 		330398 No lineage information
Host Listeria monocytogenes
[NCBI] 		1639 Firmicutes > Bacilli > Bacillales > Listeriaceae > Listeria >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
DQ003641 [NCBI]
CDS location
range 19450 -> 20325
strand +
CDS
ATGGCACGAAAATTTACAAAAGCTGAACTGGTAGCTAAAGCAGAAAAGAAAGTCGGTGGATTAAAACCCGACGTAAAGAAAGCAGTATTGTCCGCAGTGAAGGAAGCATATGACCGCTATGGTATTGGGATTATCGTATCACAGGGTTATCGTTCAATTGCTGAACAAAACGGATTGTATGCACAAGGTCGGACCAAACCGGGGAACATTGTGACCAACGCAAAAGGTGGACAATCTAACCATAACTTTGGTGTTGCCGTTGACTTTGCTATTGACTTGATTGACGATGGTAAAATCGACTCTTGGCAACCATCAGCAACCATTGTGAACATGATGAAACGTCGTGGGTTCAAATGGGGCGGAGATTGGAAAAGCTTTACTGACCTTCCACATTTTGAAGCTTGTGACTGGTATCGCGGGGAACGCAAGTATAAAGTGGACACATCTGAATGGAAAAAGAAAGAGAATATCAATATCGTTATTAAAGATGTTGGTTACTTCCAAGACAAACCTCAATTCTTAAACTCCAAATCGGTTCGTCAGTGGAAGCATGGCACGAAAGTGAAGCTTACTAAACATAACTCACATTGGTACACTGGTGTGGTCAAGGATGGTAACAAATCAGTCAGGGGATATATTTATCATTCGATGGCTAAGGTCACAAGCAAGAATAGCGACGGTTCGGTTAACGCAACGATTAACGCCCACGCATTTTGTTGGGACAATAAAAAACTTAATGGTGGCGACTTTATCAACTTGAAGCGTGGTTTTAAAGGTATCACCCATCCCGCTAGTGACGGTTTCTATCCACTGTATTTCGCTTCTAGGAAAAAAACTTTCTACATTCCGCGTTACATGTTTGACATCAAGAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
6S3Y
Method PDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
6S4S
Method PDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
6THJ
Method PDB
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A8ATR6
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi00015c022a_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (41cMd) rather than this protein.
PDB ID
41cMd
Method AlphaFoldv2
Resolution 91.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50