Protein

Protein accession
E7D0G0 [UniProt]
Representative
51zXL
Source
UniProt (cluster: phalp2_3696)
Protein name
N-acetylmuramoyl-L-alanine
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYLKTFPIAGHHNADSGAVYNGRKEADLTKEARNLFVKYFPNGKNELILDRDNETNTQLQRRIKPGAGSVLLDIHFNAGPTTATGTECLVNRKDFVNKNSMSYRMADEISKATSEILGIPNRDVKCESTTRHGRLGILNLGTGCAVLWEICFISNPNDMKQWDLKKEILMKKIAEIAAKYDDIR
Physico‐chemical
properties
protein length:184 AA
molecular weight:20691,0 Da
isoelectric point:8,84
hydropathy:-0,50
Representative Protein Details
Accession
51zXL
Protein name
51zXL
Sequence length
178 AA
Molecular weight
19672,14080 Da
Isoelectric point
5,94169
Sequence
MIYVTAGHSNQDPGASGNGYTEAALAKEFRDLVLRQLSNMNIKAWFDNDNDTLNSVLQKMNPNESDVCLDIHFNAGPPTATGVEVITADRFTREELGAATRMSVNCSKILGIRNRGVKNEKDTARKMIGILRNEKGINLLLEICFISNANDMKAYQSKKRELAVEVALHVAELDNVFA
Other Proteins in cluster: phalp2_3696
Total (incl. this protein): 234 Avg length: 185,8 Avg pI: 7,72
Protein ID Length (AA) pI
51zXL 178 5,94169
102BR 191 8,75882
14SEg 185 8,57418
16dV7 217 9,64113
1AGQ1 183 9,07839
1KNC1 181 6,21616
1KPIN 181 6,52457
1KQES 187 6,42624
1KReK 181 5,65101
1KSA7 181 6,97081
1KUqb 181 5,60759
1MqyJ 182 5,95419
1MrKk 181 5,60173
1a2jd 183 7,86864
1bL5y 182 5,59946
1bRUI 185 7,03078
1bWgB 185 7,66999
1bXnn 190 9,16439
1caIP 179 8,60945
1cab0 180 7,76434
1cnqK 176 8,87022
1coiC 178 8,66953
1crkZ 181 7,00418
1gwRK 188 9,18380
1iWpZ 180 6,32336
1ix9d 180 9,14324
1jQYl 186 7,78058
1mxfI 180 7,76400
1pf02 187 7,81462
1pvny 171 8,70692
1pwUk 190 6,82951
1uJsP 237 9,19514
2259a 198 8,76868
2G9xJ 180 5,73150
2TO0h 184 6,97161
2UjZg 182 8,96073
2WBS7 179 6,96081
2YvbK 185 9,51652
2ZAjn 180 9,24459
2ZTP7 183 6,09384
2ZyNc 187 7,72183
2eNy0 188 6,10766
2f312 236 9,28520
2goXg 180 8,40611
2gq5h 181 6,96007
2gvJ1 182 8,47877
2n4UX 178 9,34516
2oNCb 184 6,52156
2wJlC 179 5,04653
30x8S 185 7,73786
31aQq 186 7,81462
33IPQ 180 8,59075
33qr8 180 9,01263
3ME7P 185 8,77997
3MMol 224 9,04919
3NsSo 251 9,00077
3ODMI 179 6,96371
3OvWD 180 8,36305
3Uxvo 184 5,76549
3VCMG 182 6,21423
3VPhm 175 6,64979
3XUFr 180 8,88556
3bZJQ 179 7,75678
3bxPL 189 8,83148
3hPq9 182 6,30682
3xDHS 185 8,77848
41ZVX 177 9,18753
44F2w 180 9,27096
49CkY 180 9,40679
4BSQp 181 6,11783
4CU5I 181 5,83943
4INvB 185 7,71722
4NLK3 189 7,69858
4NOOV 189 7,73479
4NTSW 204 6,24134
4NTfH 204 7,93962
4RkX2 185 6,90335
4YMzh 185 7,94665
4YN08 181 6,97263
4aCC4 180 5,59076
4aTKP 176 7,71887
4eCk9 174 8,47735
4eFK5 181 6,43835
4etWR 184 5,11411
4fLyc 190 8,25526
4ffai 186 5,63606
4gEd4 193 5,82699
4gFH8 181 5,87564
4gG47 183 6,06952
4gJOl 181 5,63362
4gTpL 191 8,75882
4iG3s 248 9,80005
4kHSZ 234 9,26432
4kr7R 175 6,08947
4l13K 187 6,84457
4l1et 185 8,56226
4lufL 178 9,47474
4mqLP 187 7,75752
4nZ4j 194 8,54659
4p3sX 182 8,88879
4pIhq 180 8,98871
4pVAD 180 8,62485
4pWDN 180 8,64407
4ufMk 179 6,20525
4wPLr 186 8,30915
55kp3 180 8,64407
57qaP 180 8,96602
59Y5T 179 8,86010
5Cuoc 180 9,16078
5D1i0 180 9,32788
5EWdx 192 9,09709
5I5OI 218 6,82843
5INQR 267 6,96098
5IQ9O 217 5,81243
5a1mE 244 8,49037
5cOyI 179 9,29771
5cfne 181 6,84048
5d9Ib 180 8,98871
5dwAO 186 9,04338
5f3IX 180 9,32376
5fnLI 180 8,98871
5gZto 179 6,19741
5hM4Z 180 8,96628
5hMPx 180 8,62485
5iiu6 180 8,66412
5ksRx 179 9,18470
5lSSz 180 6,15893
5mxYc 183 5,64317
5ugCx 180 8,98871
6AcBs 180 8,64407
6LFYw 178 9,33149
6PqLc 178 7,01384
6Ugf5 178 5,94635
6VLj8 177 5,67460
6tcM7 163 7,75434
6xloa 180 7,80269
6ymf5 233 9,24749
6z2lR 180 7,80269
6zqIe 180 7,83879
71Rfp 188 9,15375
72e7z 187 9,01469
72e8B 184 8,84360
72e8U 187 6,90067
72tQW 180 7,00861
72vpC 179 7,75593
7C3FC 184 8,84347
7Ggc2 189 6,53241
7GmvT 178 4,45449
7LQS7 184 6,15102
7O3rK 181 7,70097
7QK76 180 5,96044
7Qiu 181 8,98427
7UIYz 193 5,95897
7UIu3 189 6,31972
7V0DS 181 7,79740
7V0tl 179 7,05187
7Vl8B 185 8,84424
7VlVM 186 8,51681
7X6D3 192 6,06429
7Ygup 190 9,33697
7aMcZ 185 8,62382
7bcMI 179 7,67943
7d0Nt 180 5,75014
7dYFp 185 6,95365
7dqvl 182 5,95391
7e2CP 180 6,58687
7e5a5 182 6,42488
7i7X3 185 9,14763
7kSn5 184 8,63349
7kqkj 182 9,39506
7lNSb 180 8,31289
7nIWO 187 6,30170
7omNz 179 8,79853
7owsM 186 6,89505
7qV1n 180 6,37690
7qZ6x 186 6,95410
7s5AJ 187 8,98704
7s5Bz 181 8,64503
7s5yi 184 9,01469
7sDv1 179 8,60945
7sgEG 185 6,20906
7sq4I 184 9,36824
7sq4m 187 8,95719
7sq5T 187 8,39328
7t92u 185 6,95365
7uUT0 179 8,94623
7vI3W 179 6,23515
7vL7a 180 6,64643
7vyAf 185 9,18392
7vzXV 175 9,13261
7wBw1 179 7,75218
7wBwn 181 6,58692
7xdUB 179 8,69300
7xdUD 178 8,40579
7xe0Y 187 6,42442
7yGtj 178 7,01054
7z9hn 180 7,70119
7zKxI 187 9,45347
82H02 181 5,21034
82oNv 190 6,83014
83HeU 181 5,60992
895ci 190 7,62691
89kKm 180 8,94552
8buAi 180 9,18470
8cGy4 181 5,66869
8eJ0j 186 5,64118
8k93T 178 9,34516
8kIiL 181 5,45657
8mjJy 190 8,51797
8oWMe 193 6,31961
8oWyo 202 7,65919
BaTd 181 7,70097
FN6L 178 9,47474
FOet 180 9,01263
KrcY 180 8,66412
M57X 180 8,88556
RPzN 180 8,62537
SG2c 179 4,92660
Tf9J 186 6,43141
TfgO 194 5,37546
dEgq 243 9,12249
eR4a 178 9,02366
eTWM 185 8,79209
jRrs 180 9,32343
jSGO 181 9,45759
rk3u 181 7,00475
twKJ 181 7,82048
ufVz 182 7,06886
x3c2 184 5,96596
xwUU 189 6,84060
zWZO 195 9,16839
A0AA47L0P2 184 8,84360
A0AAF0BYI7 184 8,84360
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_14862
15a1
 46 43,7% 176 1.579E-72
2 phalp2_32223
7cpfr
 3 39,5% 172 5.694E-59
3 phalp2_29815
2324Y
 17 36,8% 182 1.241E-53
4 phalp2_37678
3Xhrk
 501 35,0% 180 1.490E-42
5 phalp2_34447
4ANo2
 39 26,7% 176 1.541E-33
6 phalp2_8398
FTYz
 2 30,1% 116 4.878E-32
7 phalp2_6374
7yZe6
 41 36,0% 172 2.344E-31
8 phalp2_29178
7BEyZ
 91 31,6% 180 6.012E-31
9 phalp2_23090
4q8sF
 5 25,9% 181 1.013E-29
10 phalp2_18820
1lbSb
 1 32,5% 163 9.108E-29

Domains

Domains [InterPro]
Ami3
Representative sequence (used for alignment): 51zXL (178 AA)
Member sequence: E7D0G0 (184 AA)
1 178 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Riemerella phage RAP44
[NCBI] 		936152 No lineage information
Host Riemerella anatipestifer
[NCBI] 		34085 Bacteroidetes > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Riemerella >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HQ396194 [NCBI]
CDS location
range 632 -> 1186
strand -
CDS
ATGTATTTGAAAACATTTCCCATAGCAGGACATCACAATGCGGATAGTGGTGCTGTGTATAATGGACGAAAAGAAGCCGATTTGACAAAGGAAGCTAGGAATTTATTTGTTAAATATTTCCCCAATGGGAAGAATGAGCTAATACTAGACAGAGACAACGAAACTAATACACAGCTTCAAAGAAGAATTAAACCTGGGGCAGGTTCTGTCTTGTTAGATATACATTTCAACGCTGGACCTACAACAGCAACAGGTACTGAATGCCTAGTAAATAGGAAGGATTTTGTAAACAAAAATTCTATGAGTTACCGAATGGCTGACGAAATCAGTAAAGCCACATCTGAAATTTTAGGTATTCCAAATAGAGACGTGAAGTGCGAAAGTACAACACGACACGGAAGATTGGGTATATTAAATTTAGGTACAGGTTGTGCTGTGCTTTGGGAGATATGTTTTATCAGCAATCCTAACGATATGAAACAATGGGATTTAAAGAAAGAAATTCTTATGAAGAAAATAGCAGAAATTGCTGCTAAATATGATGATATTAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0AAF0K3F0
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
E7D0G0
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi0001ec596d_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (51zXL) rather than this protein.
PDB ID
51zXL
Method AlphaFoldv2
Resolution 94.98
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50