Protein

Protein accession
A0A3Q8L7S6 [UniProt]
Representative
Cm1J
Source
UniProt (cluster: phalp2_27942)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MNNELPWVAEARKYIGLREDTSKTSHNPKLLAMLDRMGEFSNESRAWWHDDETPWCGLFVGYCLGVAGRYVVREWYRARAWEAPQLTKLDRPAYGALVTFTRSGGGHVGFIVGKDARGNLMVLGGNQSNAVSIAPFAVSRVTGYFWPSFWRNKTAVKSVPFEERYSLPLLKSNGELSTNEA
Physico‐chemical
properties
protein length:181 AA
molecular weight:20380,0 Da
isoelectric point:9,14
hydropathy:-0,37
Representative Protein Details
Accession
Cm1J
Protein name
Cm1J
Sequence length
250 AA
Molecular weight
27724,84780 Da
Isoelectric point
9,36805
Sequence
MKNVFFTISKGINTMDLKGWIKGAFNIDKLVKPTEPAKVETPKVEPTPAPKVEETKPVAKPATTKPSTGQLEELPWIAELRKHIGLAEIKGPRHNPTIIQWLKDMGKYSGENKSWYYEDESAWCGLAVGHALGVSGRFVVPEWFRALKWSDEKYLTKLDKPAYGCIGVKERKGGGHVFFVVGLISPGYVACLGGNQGDKVSIIPIAIKDIKGFYWPSKWENKQCVKQTPNPLRYDLKIVSATGRLGASEA
Other Proteins in cluster: phalp2_27942
Total (incl. this protein): 135 Avg length: 183,5 Avg pI: 9,19
Protein ID Length (AA) pI
Cm1J 250 9,36805
1MDM4 179 9,28024
1ce2A 180 9,21958
1cr8A 180 9,46262
1jTuD 179 9,33807
1jU0S 182 9,14092
1km9C 184 9,02430
2Zzzt 173 9,24897
3egYE 178 7,82654
4erWY 162 6,56271
5NxCh 180 9,33891
5YStr 180 9,35915
5ZEoR 180 9,44431
61fvl 179 9,33891
64QTe 185 9,20217
66oVt 180 9,45540
6U45M 184 6,82167
6Z34o 184 8,68088
6ZfY3 247 9,31228
6is54 180 9,33858
6m5DO 180 9,21977
6oO4j 180 9,33891
6pGIr 180 9,33858
70Znd 179 9,30068
70iLC 179 9,40254
716u2 180 9,21958
76qzV 180 9,33891
79yMR 179 9,25735
7AVhZ 179 9,15175
7AVhm 179 9,23718
7BElS 162 9,19456
7BEmB 164 9,32318
7BFpn 179 9,32266
7BGUu 179 9,25684
7BTr0 180 9,23743
7MqFD 179 9,30068
7MsMr 243 9,30068
7NM8E 182 9,29997
7NREV 180 9,23853
7OKyE 180 9,21771
7ON8e 244 9,37791
7P46r 237 9,25000
7UP07 182 9,17703
7c8oX 179 9,19417
7d1kj 179 9,33807
7eLWT 179 9,25677
7eSh4 178 9,25677
7eSh8 179 9,32266
7elkZ 179 9,19417
7ezq9 179 9,19417
7fPS7 179 9,35799
7fYTe 178 9,25677
7gh93 179 9,32266
7gha1 179 9,35799
7hIet 182 8,93927
7hKDM 178 9,32266
7hfNM 179 9,25677
7hnQm 177 9,27753
7igiJ 179 9,17238
7imGe 178 9,25677
7kMHF 179 9,29919
7mIn3 182 9,17374
7mIvL 182 9,01437
7mIxD 182 8,95190
7mqks 177 9,19417
7pwjG 179 9,44393
7qv3J 179 9,33891
7r16o 180 9,33813
7rqG6 182 9,06782
7u15J 179 9,23718
7uJy3 179 9,25684
7uXCT 180 9,23769
7uwbz 180 9,23756
7uwiA 179 9,25677
7vKMM 182 9,31911
7vbOG 179 9,27753
7vc5B 179 8,95803
7vpER 179 9,37965
7wpJT 179 9,29919
7wpLz 179 9,13261
8I6jE 179 9,60271
8dUGp 182 9,01437
8ljNB 182 9,17393
BEaD 184 8,96512
BIqK 184 8,60603
C7nI 179 9,26296
CI8w 186 9,27863
DT79 180 9,33891
HBsx 199 9,55816
HM2J 149 9,58962
HN83 243 9,36405
Hov1 179 9,35850
JRkm 184 9,03829
KF5R 184 8,80311
KQaY 180 9,44367
KbFR 184 8,96499
Kyea 184 9,03784
KygD 181 9,06865
N205 169 9,26387
NCaC 179 9,31892
NKpk 179 9,33897
NqBj 179 9,31944
O3iD 180 9,33891
O9Xp 179 9,30068
OLfQ 180 9,33891
OOQU 184 8,96499
Ohhd 243 9,31241
OiTX 180 9,35908
OiqG 258 9,53199
OkfG 180 9,33858
UZmd 182 9,04487
pnKj 180 9,30068
t0rq 170 9,30016
tpha 179 9,44431
vgrf 164 9,51400
wTJW 180 9,31944
wWYb 182 9,28018
wYtz 180 9,33891
wZaL 195 9,44837
weMc 163 6,82730
yayJ 179 9,40325
yedQ 179 9,31892
yr6Z 184 9,36605
zhc5 180 9,33891
H6WTZ1 181 9,14228
A0A060RFI8 204 9,59749
A0A0M3MYZ4 181 8,90458
A0A3Q8KTS7 181 8,90458
A0A6G9LKB8 181 9,14228
A0A6G9LN58 181 9,14228
A0A6G5XWF2 179 9,46546
A0A6G5YGY2 179 9,33736
A0A9X9JTN6 181 9,32492
A0AAX4QCR0 181 9,14183
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_8184
76Uj5
 62 43,8% 187 1.746E-61
2 phalp2_32166
6PqA1
 486 41,3% 191 2.094E-51
3 phalp2_35973
5kZXR
 1764 39,4% 180 5.360E-51
4 phalp2_38714
WdJZ
 70 33,8% 183 2.360E-41
5 phalp2_39271
47VoK
 404 33,1% 196 7.840E-33
6 phalp2_21029
9AcO
 22 34,0% 191 2.847E-30
7 phalp2_11155
5BBbB
 16 33,3% 183 8.587E-29
8 phalp2_20540
4muWr
 288 34,2% 178 3.509E-27
9 phalp2_21703
3iJm5
 22 33,3% 156 8.862E-27
10 phalp2_6529
OOeN
 1 29,8% 171 1.643E-26

Domains

Domains [InterPro]
Disordered region
Unannotated
Representative sequence (used for alignment): Cm1J (250 AA)
Member sequence: A0A3Q8L7S6 (181 AA)
1 250 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage vB_PaeS_SCUT-S4
[NCBI] 		2488702 Septimatrevirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK165658 [NCBI]
CDS location
range 511 -> 1056
strand +
CDS
ATGAATAACGAACTTCCTTGGGTAGCCGAAGCCCGAAAGTATATCGGCCTTCGCGAAGACACTTCGAAGACTTCGCATAACCCGAAGCTTCTTGCCATGCTTGACCGCATGGGCGAATTTTCCAACGAATCCCGCGCTTGGTGGCATGACGACGAAACGCCTTGGTGCGGTCTGTTCGTCGGCTATTGCTTGGGCGTAGCCGGGCGCTACGTCGTCCGCGAATGGTACAGGGCGCGGGCATGGGAAGCCCCGCAGCTTACCAAGCTTGACCGGCCCGCATACGGCGCGCTTGTGACCTTCACGCGAAGCGGCGGCGGCCACGTCGGTTTTATTGTGGGCAAGGATGCGCGCGGTAATCTTATGGTTCTTGGCGGTAATCAGTCGAACGCCGTAAGTATCGCACCGTTCGCAGTATCCCGCGTAACCGGCTATTTCTGGCCGTCGTTCTGGCGAAACAAGACCGCAGTTAAAAGCGTTCCGTTCGAAGAACGTTATTCGCTGCCGCTGTTGAAGTCGAACGGCGAACTTTCGACGAATGAAGCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001545fed_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (Cm1J) rather than this protein.
PDB ID
Cm1J
Method AlphaFoldv2
Resolution 79.26
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50