Protein

Protein accession
Q0GXT8 [UniProt]
Representative
13d0S
Source
UniProt (cluster: phalp2_27991)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNITDAGLRGYDPKGIVIHNDAGSDYATPNFYRNWLPPRNKELGFAHVYMSNTDRLQAADFNLKAWHAGNSYANANYASWEVCQSSGNLAQFLKNEQAVLDDVAKYMKQWGLTPNRDTVKLHRELSSTSCPARSVSVHGNTLEATRTYFINELQRRIGASNNANISNPQNNNSDNSLFIPNYTPEEEIQDMMLFYTVDTKRWYISDGVNIRYIRTTRVLASYQDKWAKMKLKTDNVLQVELDTEFGKAATSTAAPK
Physico‐chemical
properties
protein length:256 AA
molecular weight:29036,0 Da
isoelectric point:7,74
hydropathy:-0,65
Representative Protein Details
Accession
13d0S
Protein name
13d0S
Sequence length
314 AA
Molecular weight
35110,76010 Da
Isoelectric point
10,36176
Sequence
MSNFRPGIVGARPGAPRFVVIHNDAGSQNATTAFYRGWLPTRQATLGFAHVYIASDGRWQAESYNNMAWHAGNTNANTWGVSWEVCQSMGNEATFRANEQAVFRDVADFMKKYNLQPNRDTVRLHREFSATACPHRSWELHGRDVNRVKDYFIQEIRKYMGQQTSAPQPAPQSPSGKTLEQLATEVQQGKWGSGTARQQALGSLFTGVQAIVNERAKVNSAAQTHQILANETRAGRFGNGADRQRLLGTYFNRIQEIINQGTAPAPAQQFHVVQRGETLSGIASRYGTTWQNLQRLNNLSNPNVIQIGQRLRVR
Other Proteins in cluster: phalp2_27991
Total (incl. this protein): 3 Avg length: 282,3 Avg pI: 9,25
Protein ID Length (AA) pI
13d0S 314 10,36176
1Enzq 277 9,64010
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2897
yopH
 100 35,8% 243 6.902E-36
2 phalp2_11417
eYHn
 21 29,4% 268 4.853E-28
3 phalp2_15359
1El58
 3 33,8% 201 1.376E-26
4 phalp2_1607
7ZyR0
 345 33,9% 271 2.856E-25
5 phalp2_20487
3X7ua
 81 34,0% 261 5.950E-21
6 phalp2_14279
3nRBR
 57 30,3% 231 5.685E-18
7 phalp2_16495
6RQrs
 8 25,4% 291 2.348E-12
8 phalp2_19215
3ui7r
 7 23,8% 293 4.197E-12
9 phalp2_17723
7dMkh
 30 29,0% 244 1.002E-11
10 phalp2_35358
7w8YM
 8 24,8% 254 1.009E-08

Domains

Domains [InterPro]
Ami2
CW_7
LysM
Representative sequence (used for alignment): 13d0S (314 AA)
Member sequence: Q0GXT8 (256 AA)
1 314 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01510, PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactococcus phage Q54
[NCBI] 		382685 Questintvirus > Questintvirus Q54
Host Lactococcus lactis
[NCBI] 		1358 Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
DQ490056 [NCBI]
CDS location
range 22146 -> 22916
strand +
CDS
ATGAATATCACAGACGCGGGCTTACGCGGTTACGACCCTAAAGGCATTGTTATTCATAATGACGCCGGGAGCGACTACGCAACCCCAAACTTTTATAGAAACTGGCTTCCACCACGTAACAAAGAATTGGGTTTTGCTCATGTTTATATGTCAAACACTGATAGATTACAAGCAGCAGACTTCAATTTAAAAGCATGGCACGCCGGAAATAGCTACGCTAATGCTAACTACGCGTCGTGGGAGGTTTGCCAATCTAGCGGGAACTTAGCACAGTTCCTTAAAAATGAACAAGCGGTATTAGATGATGTAGCTAAATACATGAAACAATGGGGGCTAACCCCAAATCGTGACACAGTAAAATTACACCGTGAACTCTCTAGCACAAGTTGTCCGGCTAGATCTGTATCAGTTCATGGTAACACTTTAGAAGCTACTCGAACATACTTCATTAACGAACTTCAAAGACGCATAGGAGCGTCAAATAACGCCAATATAAGCAACCCACAAAACAATAATAGCGACAATTCGTTATTTATTCCAAACTACACACCAGAAGAGGAGATTCAAGACATGATGTTATTTTACACAGTAGACACAAAACGTTGGTACATTTCGGACGGGGTAAATATTCGTTACATTCGTACAACCCGCGTATTAGCAAGTTATCAAGACAAATGGGCTAAGATGAAGCTCAAAACTGATAACGTGTTACAAGTAGAATTAGACACGGAATTCGGTAAAGCAGCAACAAGCACAGCAGCACCAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0000dd5052_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (13d0S) rather than this protein.
PDB ID
13d0S
Method AlphaFoldv2
Resolution 90.37
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50