Protein

Protein accession
E5EYD9 [UniProt]
Representative
4q8sF
Source
UniProt (cluster: phalp2_23090)
Protein name
Putative N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTIVTVTAGHSNSDPGACAFGRRESDIAVDMREMVKVYLEREGLTVRTDGDDRKENQTLSEAIRLIKGSKLAVEFHCNAFSKPTAGGTEVLAQDKDKAIAKAICKAISETMGIAVRGADGGWKSEGSGQHSRLGYVRNGGLIIELFFISNPNELKVWDEKKWLVAKAVAKAIIDHVK
Physico‐chemical
properties
protein length:177 AA
molecular weight:19230,8 Da
isoelectric point:8,40
hydropathy:-0,26
Representative Protein Details
Accession
4q8sF
Protein name
4q8sF
Sequence length
250 AA
Molecular weight
27050,72670 Da
Isoelectric point
9,16729
Sequence
LKYGDRGPLVVKLQQALQAHKLLPQNTGKVKHDDGIFGRGTENAVKAFQKIIGVDQTGIVGNYFAQKIGININPMKTIVLTAGHNNKDSGAVSKDQKWTEAKIVTDLRNRVKTILEAYGYTVITDGKGEENLSLSKAVALIPMGEVAIELHLNAAVSEQANGIEALAKSNLKSKCQTLCKSISDDMKYKIRGADGGWKSTDSGQHSRLAFCEAGGIILEVFFISNKAELDSYINNPDRVAKAIADAIKKL
Other Proteins in cluster: phalp2_23090
Total (incl. this protein): 5 Avg length: 238,4 Avg pI: 8,63
Protein ID Length (AA) pI
4q8sF 250 9,16729
11Ag4 251 7,69057
4Hd4u 260 8,94107
76lab 254 8,96995
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37678
3Xhrk
 501 47,7% 176 1.745E-64
2 phalp2_29178
7BEyZ
 91 40,6% 177 5.122E-45
3 phalp2_3696
51zXL
 234 34,0% 182 1.827E-29
4 phalp2_14862
15a1
 46 30,6% 186 1.020E-27
5 phalp2_11016
4Prl3
 67 27,4% 182 6.135E-11
6 phalp2_15683
35AAr
 164 27,5% 189 2.997E-08

Domains

Domains [InterPro]
PG_1
Ami3
Representative sequence (used for alignment): 4q8sF (250 AA)
Member sequence: E5EYD9 (177 AA)
1 250 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Acinetobacter phage Ac42 (Acinetobacter phage 42)
[NCBI] 		762660 Straboviridae >
Host Acinetobacter
[NCBI] 		469 Proteobacteria > Gammaproteobacteria > Pseudomonadales > Moraxellaceae >
Host Acinetobacter sp.
[NCBI] 		472 Proteobacteria > Gammaproteobacteria > Pseudomonadales > Moraxellaceae > Acinetobacter >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM032710 [NCBI]
CDS location
range 10525 -> 11058
strand -
CDS
ATGACTATTGTAACTGTAACAGCAGGACATTCTAATTCAGACCCAGGTGCTTGTGCATTTGGACGACGCGAATCAGACATTGCTGTCGATATGCGCGAAATGGTTAAGGTCTATCTCGAAAGAGAAGGCCTTACTGTGCGTACTGATGGTGATGATCGTAAAGAAAACCAAACACTAAGCGAAGCTATTCGACTTATTAAAGGTTCAAAACTTGCGGTTGAGTTTCATTGTAACGCATTTAGTAAACCAACAGCGGGTGGCACAGAAGTTCTAGCTCAAGACAAGGATAAAGCCATCGCTAAAGCTATTTGTAAAGCTATTTCAGAAACTATGGGAATTGCTGTACGCGGTGCAGATGGTGGCTGGAAATCTGAAGGTTCTGGTCAACACTCTCGCTTAGGCTATGTTCGTAATGGCGGCTTAATCATTGAACTATTCTTCATTTCCAATCCAAACGAATTAAAAGTTTGGGACGAAAAGAAATGGCTTGTTGCTAAAGCGGTTGCTAAAGCAATTATTGATCACGTAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001ebcc73_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (4q8sF) rather than this protein.
PDB ID
4q8sF
Method AlphaFoldv2
Resolution 94.21
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50