Protein

Protein accession
Q8W6M2 [UniProt]
Representative
6Rshc
Source
UniProt (cluster: phalp2_1021)
Protein name
Uncharacterized protein orf5
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTCGSTKEPHLMTAKSVIPAEWLPPAKMLRIICHWTAGNHKATSFDREHYHLLVEGDGTLVRGLPSITLNEAPAKKGYAAHTLNCNSGSIGVSLCCMAGATEAPFAAGSAPMTPIQWSKLASVVAELCRHYRIDVTPKTVLSHAEVQPNLGILQRGKWDYTRLPFDPSVKGATAVGDRLRAAVKADL
Physico‐chemical
properties
protein length:187 AA
molecular weight:20126,1 Da
isoelectric point:8,94
hydropathy:-0,08
Representative Protein Details
Accession
6Rshc
Protein name
6Rshc
Sequence length
245 AA
Molecular weight
26029,62750 Da
Isoelectric point
9,08174
Sequence
MKTTVQALQRRLIALGFPLPKFGADGDPGGETIAAVGKALDELQKLRALSEPLFPAGTSASTVAAARERLGLGGAVPSEWMPAAKMGRIICHWTAGAHKASEFDRGHYHILIEDDGKLVRGIPSIALNEAPAKKGYAAHTLGANSGSIGISLCCMGGANEAPFDPGKYPMTREQWDALTSVVADLCRRYAIPVTDKTVLSHAEVQNNLGIQQRGKWDFTRLAFDPSVKGAKACGDKLRAEAKAKL
Other Proteins in cluster: phalp2_1021
Total (incl. this protein): 90 Avg length: 231,4 Avg pI: 8,18
Protein ID Length (AA) pI
6Rshc 245 9,08174
11JZL 228 9,45205
1ItSR 229 4,74057
1NRij 237 6,21974
1NVl1 240 6,12869
1bbeD 243 4,58346
1bdLo 243 4,58346
1blIA 222 4,73062
1dC8J 227 4,78166
1j7sq 242 8,62021
1qZ9S 243 8,79093
1qn5i 243 9,33704
242Cg 243 8,89833
2SBIX 253 5,24012
2VLFF 245 8,24952
2YHQ1 230 7,00321
2cGvJ 245 8,25171
2cGwN 230 8,24965
2suBx 241 9,22299
3OL1M 220 9,51187
40vXh 239 9,02894
4CyKc 267 10,02246
4U2A1 255 9,70902
4U2Sc 241 9,44663
4W39F 275 8,59559
4Wtz3 215 5,80732
4o0BO 234 8,97788
4uDMS 249 9,61683
5As3v 234 4,71647
5AsPO 232 4,93569
5GUtx 230 4,41738
5qQEx 226 5,59520
6Khjz 230 4,41539
6QWqK 244 9,44025
6RA3K 176 8,53956
6RpnX 243 9,18425
6RqKb 243 9,20107
6RqMe 234 8,69525
6RqZv 176 8,53956
6RqsN 243 9,08039
6RqyR 243 9,26212
6RsHN 252 9,42162
6RtS6 241 9,35760
6RuMm 235 8,90445
6Rzjx 245 8,30838
6T1i4 240 8,38761
71BZy 176 9,41472
71TkE 239 8,95758
72bat 238 6,99992
75sGB 236 9,11075
79w39 178 8,75302
7B7zk 187 8,94294
7LH2a 256 9,25606
7cuTB 252 9,21513
7dBHN 243 9,21848
7dByZ 243 9,18425
7doVC 235 8,86120
7dxMT 240 9,01257
7faNj 233 8,19169
7i6WL 176 9,25529
7i71Y 245 9,00883
7kSBF 232 8,20014
7m6RW 237 8,81439
7p0Zw 243 9,34381
7pYpM 256 9,50865
7pZIh 241 9,02798
7po9h 244 9,27328
7rMN5 233 9,19218
7sOoJ 235 8,85120
7si0P 233 7,63401
7t1nF 231 8,22876
7t1pZ 245 7,68051
7tK1Y 235 8,93985
7taAk 227 8,32804
7taFd 231 8,55297
7tar5 235 8,16758
7vE0H 239 8,74212
7woHx 237 8,78042
7yh4V 226 9,19424
7z7it 174 8,92953
7zqDC 238 9,12500
7zr46 238 9,09651
81e8W 241 7,04703
8J5Ej 233 7,66277
RyF7 227 5,79089
Sno7 227 4,63519
e8bY 177 9,31976
fYnW 185 9,51175
A0A6G5YAG9 174 8,92521
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9404
8Fz4V
 29 69,0% 171 3.528E-95
2 phalp2_19974
6PE0f
 7 67,8% 168 1.990E-86
3 phalp2_20043
1rrOC
 14 42,2% 251 3.061E-84
4 phalp2_21458
8eHRi
 401 58,1% 177 4.841E-76
5 phalp2_22282
7wBZw
 14 46,9% 164 1.016E-49
6 phalp2_3022
1KBl0
 18 36,7% 188 3.283E-40
7 phalp2_26583
8s4n7
 984 33,1% 166 7.843E-14
8 phalp2_21712
3mZuj
 73 25,1% 215 2.810E-08
9 phalp2_11261
6Jhk9
 16 25,5% 188 2.926E-07

Domains

Domains [InterPro]
Unannotated
Ami2
Representative sequence (used for alignment): 6Rshc (245 AA)
Member sequence: Q8W6M2 (187 AA)
1 245 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Sinorhizobium phage PBC5
[NCBI] 		179237 No lineage information
Host Sinorhizobium meliloti
[NCBI] 		382 Proteobacteria > Alphaproteobacteria > Rhizobiales > Rhizobiaceae > Sinorhizobium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
AF448724 [NCBI]
CDS location
range 3308 -> 3871
strand -
CDS
ATGACGTGCGGCTCAACGAAGGAGCCCCACCTCATGACCGCCAAAAGCGTAATCCCCGCTGAATGGCTACCGCCAGCGAAGATGCTTCGCATCATCTGCCATTGGACCGCCGGCAATCACAAAGCCACCAGCTTCGATCGCGAGCACTACCATTTACTGGTAGAGGGAGATGGCACGCTAGTTCGCGGCCTGCCTTCAATCACCCTCAACGAGGCCCCCGCCAAGAAGGGCTATGCAGCCCACACCCTGAATTGCAACAGCGGTTCTATCGGAGTGTCGCTCTGCTGCATGGCGGGCGCCACCGAAGCGCCGTTTGCAGCCGGTTCCGCTCCCATGACGCCGATCCAGTGGAGCAAATTGGCATCCGTGGTCGCGGAACTGTGCCGCCATTACCGAATCGACGTGACGCCAAAGACGGTGCTTTCCCACGCGGAAGTGCAGCCAAATCTCGGTATCCTGCAACGCGGGAAATGGGACTACACCAGGCTGCCGTTCGATCCATCCGTGAAGGGAGCCACTGCAGTCGGCGACCGTCTTCGGGCTGCAGTGAAGGCGGATCTTTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000009c1c5_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (6Rshc) rather than this protein.
PDB ID
6Rshc
Method AlphaFoldv2
Resolution 91.42
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50