Protein

Protein accession
A0A649VFI4 [UniProt]
Representative
1ruqi
Source
UniProt (cluster: phalp2_4095)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTTKDQVAQITIAEAKARGYTRSECLAIMSTFYQESGWNDTIWDPTHTTYGIAQQDGSYPHRFDGAAAQIKGFFDKLDVWRAKPGASTDIWLNICWMQQAPNWPSADYWYANGRRAYLTEIKSRIATVTPYLDKYWPADGGTAVPDEPRPDFNEFALWSSNSSARSGKPTMFLIHTQEGGGGDAAAENLAKWFQNGNGVSYHYTISQASDGGVTVVDCVDTDRAAWSVGNANSISINLCFAGSRASWSRDQWMKQSNAIDVAAYLAVQDAKKYGFEPLVVPPPYVNGRPGISDHRWVTDVFKWGTHTDVGDWFPWDYFTERVNHWANGGKTEPEPPKVKRFPDDWTDREILIEVLRQLRGYNLDGWPQLGGKSLVDAVAEIRNVVCDK
Physico‐chemical
properties
protein length:388 AA
molecular weight:43531,9 Da
isoelectric point:5,34
hydropathy:-0,53
Representative Protein Details
Accession
1ruqi
Protein name
1ruqi
Sequence length
125 AA
Molecular weight
14302,80720 Da
Isoelectric point
6,89164
Sequence
VTTKDQVAQITIAEAKARGYTRSECLAIMSTFYQESGWNDTIWDPTHTTYGIAQQDGSYPHRFDGAAAQIKGFFDKLDVWRAKPGASTDIWLNICWMQQAPNWPSADYWYANGRRAYLTEIKSRI
Other Proteins in cluster: phalp2_4095
Total (incl. this protein): 71 Avg length: 385,0 Avg pI: 5,55
Protein ID Length (AA) pI
1ruqi 125 6,89164
7ud76 167 5,04943
A0A481W3X4 360 5,11513
A0A385DQI6 397 5,45338
A0A7M1CMH0 384 5,64391
A0A482JH45 383 5,78078
A0A5P8PJF4 402 5,50323
A0A5J6T552 397 5,24507
A0A385E1C5 398 5,70029
A0A5P8DAL4 397 5,44264
A0A7G9W133 396 5,92611
A0A097EVH7 402 5,79669
S5VMP7 384 5,51971
A0A2D1GH84 397 5,65482
S5XXS1 388 5,23722
A5YJZ8 403 5,07830
A0A346FBX0 397 5,45338
G1D4E5 396 5,84677
A0A3G8FJX8 397 5,53301
A0A0K1LS89 397 5,53830
A0A1D8EXR4 397 5,44719
Q9FZS0 384 5,51971
G1DU08 384 5,51971
A0A2P1CHJ0 397 5,31202
A0A2P1N3H3 400 5,36341
A0A0H4TI64 387 5,68915
G8I4V3 384 5,51971
A0A076YKD5 387 5,92617
A0A142K6J9 386 5,15930
A0A649VFB9 403 5,22773
A0A2S1PBY7 384 5,51971
A0A2Z5H6D8 398 5,62839
A0A386KRX7 388 5,55751
A0A385DZ80 389 5,74542
A0A482JJ51 403 5,14804
A0A481VUK3 397 5,56689
A0A5Q2WIJ8 388 5,43627
A0A649V7W8 388 5,69245
A0A649V752 388 5,43627
A0A7D5JKK1 393 5,66840
A0A088FVW8 397 5,44719
A0A7G9UXW2 384 5,51971
R4JPZ6 398 5,87001
A0A385DR99 396 5,78936
G1JZ48 397 5,16794
A0A1W6JTM5 388 5,22245
A0A2D1GA44 397 5,65482
A0A2R4AQK2 389 5,74542
A0A2S1PB03 398 5,87001
A0A386KRM7 384 5,64391
A0A3G3LZ22 384 5,51971
A0A411BTF1 397 5,44719
A0A4Y6EM49 385 5,61867
A0A5J6D9H3 384 5,55353
A0A5J6T3H5 402 5,50323
D4N7H4 384 5,64391
A0A8T8JDS3 384 5,51971
A0A977KN30 396 5,43627
A0A9E7QHS4 396 5,69245
A0A9E7TXE6 384 5,55353
A0A9E8S2N5 398 5,87001
A0AA49B3W5 397 5,53301
A0AA96GPT2 400 5,72047
A0AA96K989 397 5,65482
A0AAE7VFK0 389 5,74542
A0AAE8XBD7 384 5,51971
A0AAE8XJ39 400 5,72047
A0AAE8XJE5 396 5,23597
A0AAE9C423 384 5,51971
A0AAX4Q1S5 384 5,51971
Similar Clusters

No similar clusters were found for representative 1ruqi.

Domains

Domains [InterPro]
Disordered region 1
Unannotated
Disordered region 2
Representative sequence (used for alignment): 1ruqi (125 AA)
Member sequence: A0A649VFI4 (388 AA)
1 125 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Strokeseat
[NCBI] 		2656607 Cheoctovirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN586004 [NCBI]
CDS location
range 26586 -> 27752
strand +
CDS
GTGACCACGAAAGATCAAGTCGCCCAAATCACCATCGCCGAAGCCAAGGCGCGCGGCTACACCCGCAGCGAATGCCTGGCGATCATGTCCACCTTCTACCAAGAGTCCGGCTGGAACGACACCATCTGGGATCCCACCCACACCACCTACGGCATTGCCCAGCAGGACGGCTCCTACCCACACCGCTTCGACGGTGCCGCAGCCCAAATCAAAGGCTTCTTCGACAAGCTCGACGTGTGGCGCGCCAAACCCGGTGCCAGCACCGATATATGGCTGAACATCTGCTGGATGCAGCAGGCCCCCAACTGGCCCAGCGCTGACTACTGGTACGCCAACGGTCGCCGCGCCTACCTCACCGAAATCAAGTCACGCATCGCCACCGTCACCCCATACCTCGACAAGTACTGGCCCGCCGATGGAGGTACCGCCGTGCCCGACGAACCACGCCCCGACTTCAACGAGTTCGCCCTGTGGTCTAGCAACAGCAGTGCCCGCAGCGGCAAGCCCACTATGTTCCTGATCCACACCCAGGAAGGCGGCGGTGGGGACGCAGCTGCCGAGAACCTGGCGAAGTGGTTCCAGAACGGCAACGGCGTCTCGTACCACTACACGATCTCCCAGGCGTCCGATGGTGGTGTGACGGTGGTCGATTGCGTCGACACCGACCGCGCCGCCTGGTCTGTGGGCAACGCCAACAGCATCAGCATCAACCTGTGCTTCGCGGGGTCGCGAGCATCCTGGTCGCGGGATCAGTGGATGAAGCAGTCCAACGCGATCGACGTCGCAGCATACCTCGCGGTGCAGGACGCGAAGAAGTACGGCTTCGAACCACTCGTGGTTCCCCCGCCGTACGTGAATGGCCGCCCAGGCATCTCGGACCACCGGTGGGTGACCGACGTGTTCAAGTGGGGCACCCACACCGATGTTGGTGACTGGTTCCCGTGGGACTACTTCACCGAACGCGTCAACCACTGGGCCAACGGTGGCAAGACCGAACCTGAACCGCCGAAGGTGAAACGCTTCCCCGACGACTGGACCGACCGCGAAATCCTCATCGAGGTTCTACGCCAGCTCCGCGGCTACAACCTCGATGGCTGGCCCCAGCTCGGCGGCAAGTCCCTCGTCGACGCCGTCGCCGAAATCCGAAATGTCGTCTGCGACAAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1ruqi) rather than this protein.
PDB ID
1ruqi
Method AlphaFoldv2
Resolution 97.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50