Protein

Protein accession
A0A343X839 [UniProt]
Representative
72syZ
Source
UniProt (cluster: phalp2_36845)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MLVQCLLINCPMEIGYEHVFDFENRQNQMYFFEHKLNANRLTTEVNTKVDGFLEKVNIKFPYANARHYDYIIIFEPGTQVPYFFFITRMKMLTKDVTELSLKLDVFQTYQFDFKFNMSFVDRCHVRRWEKYDDNIPTDNNLDEGLEYGATTIKTIENVKKMRSNYILATTTPIGKLGASTGGGGTGAGGCGDPSKGIPTNKYYRYLKGIEGLNQYPVDIGDGVTTFGYGVTKENEPTYFAKLGAPPVSEKKASEVLFELIPARYGNLVASQFKKDGINMSTVDKHKFDAFVDLCYNTGYYNSKLYKMWLAGESMDKIKSEWLVYAIMPGSIFEEGLRRRRKEEWLMFSEGTYSNSPITIHGDRGQSIGTVEGDGYMIECENVTDKYFTVNNEGGQNWIMPAEGKVTATYPVYPSGSAHSGIDVGCPEGTPVRASKDGVCIKRREITTSYGKYLFIEHAENLISIYAHNSKLLINEGDHVKAGDIIAYSGNTGNSTGAHSHFEIRVNNIAINPAPSLKVGDIIKHKGV
Physico‐chemical
properties
protein length:527 AA
molecular weight:59226,4 Da
isoelectric point:6,26
hydropathy:-0,39
Representative Protein Details
Accession
72syZ
Protein name
72syZ
Sequence length
995 AA
Molecular weight
102339,36080 Da
Isoelectric point
9,34381
Sequence
MSDIEGLIRRPTEPSPSSITPLLGTNRLQSAVDHMSKSVDKVSGWLDKASDRLAKMSAPTAGMGSGTTLNGGKQNGGGSSIGGVRMLGAGASNGAASGTPHSFLGMPYQQNIPTMTQQYGAPTQTGGKSNGGAVNWPRYGAALGGAWGAATVQAGLDRTQSFVASNTSAQLMTRSVIGGDWQRLRTGVVHDNWTATSDQDAFAGVANLRASGFTYGSRQWNSQMSQAKNYSMMDPTVSGADAGARIAAPQQIATTNYLLGRGINTRGKTGMAVADQMVDKFIKSNKSWSQKDYDSLWGAQGGARLATNQIAKVDPNAAALFQDRLQGTMQAQMHGMTKEAYRSAIDSGNWDALKQYGFSETDLNKTKEKAARQRNIDDNMAGGFSTGLNNAVDAIGAFQEALEKVTDGPLGAMAGYGHGWAGSSGLLGSATHIGGSMAGGYFGGKMASSLAKNGVKGTAINAASSGAGAVAKGASGVASVAGKAGKFMKGVPLLGLGIDAATTAFQGDERDRRKQNAMSHGWGDGMATYMSWRDTFASNLTFGLYGGAPDTQDPSSGGSAGERYGMFGTGGEKGGQAVKPVGNAPITAPFGRYKKSGKAHYGIDFGVPSGTPVRANRSGKVVVAGWSNTGFGNHVRIDIGDGTIEIYGHLSQLNVRVGQTIKAGDVIGKSGSSGNSTGPHLHFEVRKGGGGTGNAVDPSSYLKGADNPAPVSADAGSGSSVGSAGKGADGLGSARSMTASPWGVGEGQIVSGALGSLVGSMRSGSSGEGDSGAADAPSSPATAASGQFRDVLARAGFKGTSLGMAYAIMMAESGGNAHAHNTNKATGDNSYGLFQINMLGGMGPERRSKFHLANNDALFDPLTNAKVAYDMSKGGSDWHDWSTYKRGDYKKYLGGQQKSYDVGSTNIDVDQVARVHKGEMILDPVTADEMRKALSSNRPTDLFGSKGGKGGGIRIDNLTIQTAHQFTDSAATDLAKQFLSIVNNHDEVSTIMGGN
Other Proteins in cluster: phalp2_36845
Total (incl. this protein): 4 Avg length: 884,0 Avg pI: 7,67
Protein ID Length (AA) pI
72syZ 995 9,34381
4MSie 994 9,54514
I2E8W3 1020 5,51221
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_26491
27CrY
 1 27,6% 1123 4.239E-51

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage CPS2
[NCBI] 		2175605 Guelinviridae > Brucesealvirus > Brucesealvirus CPS2
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH248069 [NCBI]
CDS location
range 2999 -> 4582
strand +
CDS
ATGTTAGTACAATGTTTATTAATAAATTGCCCTATGGAGATAGGATATGAGCACGTGTTCGACTTTGAAAACAGACAAAACCAAATGTATTTTTTTGAGCATAAATTAAATGCCAATAGACTTACAACAGAGGTTAACACAAAGGTTGACGGTTTTTTGGAGAAAGTAAATATTAAGTTCCCATACGCTAACGCTAGACATTACGACTATATAATTATATTTGAACCAGGGACACAAGTACCATATTTTTTCTTTATAACACGTATGAAAATGTTAACTAAGGACGTTACAGAACTATCGTTAAAATTAGATGTATTTCAAACTTACCAATTCGACTTTAAATTTAATATGTCCTTTGTGGACAGATGTCATGTTAGACGTTGGGAAAAATACGACGATAACATACCTACAGACAACAATTTAGACGAGGGGTTGGAATACGGAGCAACAACAATAAAGACAATAGAAAATGTTAAAAAAATGCGTTCAAATTATATTTTGGCTACTACTACACCTATAGGCAAACTGGGAGCAAGTACAGGCGGGGGCGGTACTGGTGCAGGTGGTTGTGGCGACCCGTCAAAAGGAATACCAACCAATAAATATTATCGTTACTTAAAAGGTATAGAAGGGTTAAACCAATACCCAGTAGACATTGGCGACGGGGTTACAACTTTTGGGTATGGTGTAACAAAAGAGAACGAGCCGACCTACTTTGCTAAGCTAGGAGCACCCCCAGTAAGTGAGAAAAAAGCGAGTGAGGTTTTATTTGAATTAATACCTGCAAGGTATGGAAATTTAGTCGCTAGTCAGTTTAAAAAGGACGGCATTAATATGTCAACAGTAGACAAGCACAAATTCGACGCATTTGTAGACCTATGCTATAATACGGGTTATTACAACTCTAAGCTTTATAAAATGTGGTTAGCAGGTGAGAGCATGGACAAAATAAAGTCAGAGTGGTTGGTATATGCCATAATGCCTGGTAGCATATTTGAAGAGGGTCTAAGAAGGAGACGTAAAGAGGAATGGTTAATGTTTTCAGAGGGAACCTATTCAAACTCACCTATTACAATACATGGAGATAGAGGACAATCAATCGGAACAGTTGAAGGCGACGGTTACATGATAGAATGTGAAAATGTTACAGACAAGTATTTTACTGTTAACAATGAAGGGGGTCAAAACTGGATTATGCCCGCAGAAGGAAAAGTTACGGCAACATATCCTGTATATCCTAGTGGTTCGGCTCATAGCGGTATTGATGTTGGTTGTCCCGAAGGCACACCAGTTAGAGCAAGTAAAGACGGCGTGTGTATTAAGCGTCGTGAGATTACAACATCTTATGGAAAATATTTGTTTATAGAACACGCAGAAAATTTAATTTCTATTTACGCTCATAATAGTAAGCTTTTAATCAATGAAGGCGACCATGTGAAAGCGGGCGACATTATAGCCTATAGCGGTAATACTGGAAACAGTACAGGAGCACACAGTCATTTTGAAATTAGAGTAAATAATATAGCAATTAACCCTGCACCTAGTTTAAAAGTGGGGGACATTATAAAGCATAAGGGGGTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (72syZ) rather than this protein.
PDB ID
72syZ
Method AlphaFoldv2
Resolution 51.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50