Protein

Protein accession
A0A218M2W9 [UniProt]
Representative
2YvPg
Source
UniProt (cluster: phalp2_30084)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDYIVSDAGAALAMEFEGFEPAAYLDMVGVPTIGYGLTRWFGRPGKPRVQMGETIDRETAFQELVFTLQSFWDEVENRVMVPLEQYQVDALASFIYNVGTTAFLGSTMLRKLNNGDFEGAANEFQRWNKAGGQVVRGLTRRRAAEEALFRGATR
Physico‐chemical
properties
protein length:154 AA
molecular weight:17245,3 Da
isoelectric point:4,94
hydropathy:-0,21
Representative Protein Details
Accession
2YvPg
Protein name
2YvPg
Sequence length
389 AA
Molecular weight
40505,93580 Da
Isoelectric point
9,61548
Sequence
MARKTSQVGVDLIKEFEGLRLTAYQDSVGVWTIGYGHTNNTASADKYPVYAGQTISKAKAETILKADLITFENAVNNYVTVSINQNQFDALVSFSFNLGAGALRTSTLLQKLNNGDVNGAANEFGRWVNAGGVQLPGLVRRREAEKQLFLSGSTGGGGNGGNGGGSGGGSTDTYVVKSGDTLSGIAVKFGVTVSQLKKWNNISNADSIQIGQKLIVKEPSGGGGSGGSQKTYTVKSGDTLSGIAVKFGVTVSQLKKWNNISNADSIQIGQKLTVKEPSGGSGGSGGGSTETYTVKSGDTLSGIAVKFGVTTAQLQKWNNISNADSLQIGQKLIVKEPVGGSQTTYTVKSGDTLSGIAVKFNVTVSNLMKWNNISNADTIKIGQKLIIKN
Other Proteins in cluster: phalp2_30084
Total (incl. this protein): 3 Avg length: 230,7 Avg pI: 7,93
Protein ID Length (AA) pI
2YvPg 389 9,61548
A0A6J5RSI8 149 9,22254
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1915
4hcut
 54 48,6% 288 1.372E-59

Domains

Domains [InterPro]
GH24
LysM
LysM
LysM
LysM
Representative sequence (used for alignment): 2YvPg (389 AA)
Member sequence: A0A218M2W9 (154 AA)
1 389 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Acidovorax phage ACP17
[NCBI] 		2010329 Busanvirus > Busanvirus ACP17
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KY979132 [NCBI]
CDS location
range 66676 -> 67140
strand +
CDS
ATGGACTACATCGTATCGGACGCGGGCGCAGCGCTCGCAATGGAATTTGAAGGCTTCGAGCCGGCCGCTTACCTTGACATGGTGGGCGTTCCGACAATCGGCTACGGTCTGACCCGCTGGTTCGGCCGCCCCGGCAAGCCCCGCGTTCAGATGGGAGAGACCATCGACCGAGAGACGGCGTTCCAGGAACTGGTGTTCACACTCCAGAGCTTCTGGGACGAAGTTGAGAACCGCGTCATGGTCCCTCTGGAGCAATACCAAGTGGATGCACTCGCCTCGTTCATCTACAACGTGGGGACGACGGCCTTCCTGGGCTCCACGATGCTGCGCAAGCTGAACAATGGCGACTTCGAAGGCGCTGCAAACGAGTTCCAGCGCTGGAACAAAGCTGGCGGTCAAGTCGTGCGAGGCCTGACTCGCCGGCGTGCTGCTGAAGAGGCGCTGTTCCGAGGTGCGACACGATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi000b60f966_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (2YvPg) rather than this protein.
PDB ID
2YvPg
Method AlphaFoldv2
Resolution 79.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50