Protein

Protein accession
A0A222YTZ0 [UniProt]
Representative
8MCi0
Source
UniProt (cluster: phalp2_23661)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MDNSAKGNIAAASLILGVATAVFVSAASETGNFPLDSIEKPATSTSASPEATPSESEAPKAVYSPQPSLTSSPSVKPTPKVTTIRISPVAYSKSISSTKDYAKGKLKKKYPKSWKKQWNCLNPLWKHESSWNYKAKNPYSGAYGIPQSLPASKMKAAGKDWKTNPRTQVRWGLDHYIYKRYGTPCKAWGHFKNKGWY
Physico‐chemical
properties
protein length:197 AA
molecular weight:21634,4 Da
isoelectric point:9,89
hydropathy:-0,70
Representative Protein Details
Accession
8MCi0
Protein name
8MCi0
Sequence length
184 AA
Molecular weight
20289,03520 Da
Isoelectric point
9,78019
Sequence
MDQKMKGNIASMALCLGVAAAVFAQAASDMGALPLEAEKPNVTQSVSPKATPSTNESPVVNVPKITPPVTLNASPVAYSNSVKSSKDYAYSKIKGTYKKTYKTQWPCLNNLWIKESSWNYKAKNPYSGAYGIPQALPATKMASAGKDWKTNARTQINWGLHKYIYPRYGTPCNAWSHFKRKGWY
Other Proteins in cluster: phalp2_23661
Total (incl. this protein): 53 Avg length: 180,3 Avg pI: 9,86
Protein ID Length (AA) pI
8MCi0 184 9,78019
11xLj 181 9,84202
13lHa 177 10,06005
1QFDA 181 9,69658
27Qc3 181 9,39287
27vWz 167 10,21819
2YEVE 179 9,90533
38gEs 179 9,86639
48DBN 179 9,81036
49kNM 181 9,94111
49sYc 179 9,79483
4at6h 179 9,87638
4bjmM 179 9,97424
4pPcj 183 9,67201
50IC1 167 10,29478
587nG 174 9,83815
5c504 182 9,87683
5cfA7 179 9,82364
5cuwF 167 10,17558
5eIRC 183 9,37230
5g8U0 181 9,87735
5gGOl 183 9,41221
5ntBU 179 9,91313
5ntUl 183 9,59768
5w7kE 179 9,93582
6S6rp 185 10,03342
6ycMD 183 9,35348
7AdPa 197 9,89140
7AdXw 181 10,05605
7AeLU 181 9,96419
8MCtz 181 9,88405
8MCxv 181 9,96419
8lhKe 158 9,47229
8nAXO 179 9,83744
JCox 181 9,97424
aBGP 179 9,97482
A0A345M9R4 184 9,78019
A0A345M7S7 181 9,84202
A0A411C4D4 181 10,05605
A0A345M8G7 181 9,96419
A0A345MH77 181 9,88405
A0A345MG85 181 9,96419
A0A411CFP4 181 10,05605
A0A4Y6EQ98 181 9,86271
A0A5Q2WDE2 181 9,86271
A0A5Q2WJD4 181 9,86271
A0A5Q2WQ81 181 9,86271
A0A7T0M0B6 181 9,86271
A0A9E7ISD5 181 9,77987
A0AA49H3N5 191 10,05128
A0AAF0GEC3 181 9,83261
A0AAX4LUC6 180 9,70709
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33782
1b2W0
 33 47,0% 151 1.124E-43
2 phalp2_31384
2QlK7
 11 43,5% 156 1.559E-40
3 phalp2_38619
2aAe3
 5 40,7% 135 6.825E-33
4 phalp2_2932
U3n1
 1044 47,8% 115 2.914E-28
5 phalp2_6786
86lVr
 10 37,0% 154 1.526E-25
6 phalp2_14148
2iIxu
 157 34,5% 139 1.404E-19
7 phalp2_20998
7ANG1
 61 33,0% 139 3.571E-19
8 phalp2_17421
4T3CZ
 2 30,5% 167 5.147E-17
9 phalp2_701
1Dp8S
 6 33,8% 127 2.120E-15
10 phalp2_5567
3Wp4H
 119 34,4% 122 3.936E-15

Domains

Domains [InterPro]
Disordered region
Unannotated
Representative sequence (used for alignment): 8MCi0 (184 AA)
Member sequence: A0A222YTZ0 (197 AA)
1 184 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Mildred21
[NCBI] 		2023959 Stanwilliamsviridae > Samistivirus > Samistivirus mildred21
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MF155946 [NCBI]
CDS location
range 16070 -> 16663
strand -
CDS
ATGGATAACAGTGCTAAGGGCAACATAGCCGCAGCGAGTCTGATTCTCGGTGTTGCAACAGCAGTATTTGTCAGCGCAGCATCTGAGACAGGCAACTTCCCCCTTGATTCAATTGAGAAGCCTGCGACTAGCACTTCAGCATCACCAGAAGCAACACCAAGCGAGAGTGAGGCACCGAAGGCTGTATATTCACCACAGCCAAGTCTGACATCTTCACCTTCTGTTAAGCCTACGCCGAAGGTTACGACAATACGCATCAGTCCTGTTGCTTACTCGAAGTCAATTTCGAGCACGAAGGACTACGCAAAGGGTAAGCTCAAGAAGAAGTATCCTAAGTCATGGAAGAAGCAGTGGAACTGTCTGAATCCTCTTTGGAAGCATGAGTCTTCTTGGAACTATAAGGCTAAGAATCCTTATTCTGGAGCTTATGGAATTCCTCAGTCACTACCGGCCTCAAAGATGAAGGCGGCTGGAAAGGACTGGAAGACCAATCCTCGAACGCAGGTACGATGGGGTCTTGACCACTACATCTACAAGCGTTACGGTACTCCTTGCAAGGCTTGGGGTCACTTCAAGAACAAGGGTTGGTACTGA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000b948690_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8MCi0) rather than this protein.
PDB ID
8MCi0
Method AlphaFoldv2
Resolution 76.02
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50