Protein

Protein accession
A0A2Z4QC94 [UniProt]
Representative
7uiQL
Source
UniProt (cluster: phalp2_17750)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSTTPMTAQQFVDALKKEGVKVSESFKGWRTHERDDETGRTFGPVNGVVIHHTAGRDSLQLCIKGTSALPGPLCHTHLAKDATATMISAGRANHAGGFTQNAHDAVLAERKVHPRPSGAESVDGNDHYYGIEIENLGNGSDVYPAKQYDAAVRWAAAICRFHGWTAQSVIGHKEGTTRKIDPKGPVEGKGQFDMDQFRADVQKRLDAKPAPKPEPKPEPKPEPKPPVTPPKSTIVKLNPAVKPGAKHAQVKELQQLLIKAGYGPIEGAVTSFYGKNTEAAVARFHERNPKYKAYGVRRDPAIGPSGFIALQKQAGRR
Physico‐chemical
properties
protein length:317 AA
molecular weight:34367,5 Da
isoelectric point:9,56
hydropathy:-0,67
Representative Protein Details
Accession
7uiQL
Protein name
7uiQL
Sequence length
153 AA
Molecular weight
15753,55690 Da
Isoelectric point
9,03539
Sequence
VQIAIGGDQAPSDAALRSARALYDEACAKTGRQLSKHGHRDGFATECPGGRLYAWVKAGMPAPGGGGGGGTVALDPAVKPGVNHPQVRLLQELLMKAGYGPIPGAVTDFYGANTQAAVARFHDRHPEFKSAGVSHDVAIGGRGFAVLQQEAGR
Other Proteins in cluster: phalp2_17750
Total (incl. this protein): 7 Avg length: 293,4 Avg pI: 9,34
Protein ID Length (AA) pI
7uiQL 153 9,03539
A0A291LHE3 317 9,35973
A0A291LGZ3 316 9,35954
A0A291LHU5 317 9,34703
A0A345MI49 317 9,37249
A0A411CPT1 317 9,35954
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_40588
7Clcy
 7 33,8% 121 3.375E-05
2 phalp2_35681
3yvcZ
 6 27,4% 113 5.195E-04

Domains

Domains [InterPro]
Unannotated
PG_1
Representative sequence (used for alignment): 7uiQL (153 AA)
Member sequence: A0A2Z4QC94 (317 AA)
1 153 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Yosif
[NCBI] 		2201421 Yosifvirus > Yosifvirus yosif
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH248947 [NCBI]
CDS location
range 22917 -> 23870
strand +
CDS
GTGAGTACGACCCCCATGACCGCGCAGCAGTTCGTGGACGCCCTGAAGAAGGAGGGCGTGAAGGTCTCCGAGAGCTTCAAGGGCTGGCGCACGCATGAGCGTGACGACGAGACCGGTCGCACCTTCGGCCCCGTGAACGGCGTGGTCATCCACCACACCGCTGGCCGCGACAGCCTCCAGCTCTGCATCAAGGGCACCAGCGCGCTCCCCGGTCCGCTCTGCCACACGCACCTGGCCAAGGACGCCACGGCCACGATGATCTCGGCTGGCCGAGCCAACCACGCGGGCGGCTTCACCCAGAACGCCCACGACGCGGTCCTCGCCGAGCGCAAGGTGCACCCGCGCCCGAGCGGCGCTGAGTCGGTGGACGGCAACGACCACTACTACGGCATCGAGATCGAGAACCTGGGCAACGGCTCCGACGTCTACCCGGCCAAGCAGTACGACGCTGCGGTCCGCTGGGCTGCCGCGATCTGCCGCTTCCACGGCTGGACCGCCCAGAGCGTCATCGGCCACAAGGAGGGCACGACCCGCAAGATCGACCCGAAGGGTCCGGTCGAGGGCAAGGGCCAGTTCGACATGGACCAGTTCCGTGCCGACGTGCAGAAGCGTCTCGACGCCAAGCCCGCTCCGAAGCCCGAGCCCAAGCCCGAGCCGAAGCCCGAGCCCAAGCCTCCGGTCACTCCCCCGAAGTCCACGATCGTGAAGCTCAACCCGGCTGTGAAGCCCGGCGCGAAGCACGCCCAGGTCAAGGAGCTCCAGCAGCTCCTCATCAAGGCGGGCTACGGCCCGATCGAGGGTGCGGTGACCAGCTTCTACGGCAAGAACACCGAGGCGGCTGTCGCCCGGTTCCATGAGCGGAACCCGAAGTACAAGGCGTACGGTGTCCGGCGCGACCCGGCGATCGGCCCCTCGGGCTTCATCGCTCTCCAGAAGCAGGCCGGGCGGCGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7uiQL) rather than this protein.
PDB ID
7uiQL
Method AlphaFoldv2
Resolution 89.66
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50