Protein

Protein accession
A0A6G6XJF3 [UniProt]
Representative
7d3iJ
Source
UniProt (cluster: phalp2_36852)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTLFGIDVSNHQKQFDFARAKREGMVFATHKITEGDYYRDTYWARAKAEMKREFPGLWGGYVFCRRASHPKREAELLASHAGSTDFPLQIDYEDTDGGGSYDDMVARYEAYRAVGFTQFLPIYLPRWFWQGRMGAPDLRDFPLPVWNSDYGSSRAGNYKAIYPGDDNGGWASFKGKPVALLQYTERGNVAGQAIDVNAFRGSMQDLQELFGGGKDMAVEHEILRQETGSLEVGKFPGHKTRRHEGSVQGSFTQTDLMREMDRELNSVFSLEGRPVDPSKGDTVVGHVLSLRAEVAELRKLIEEKLK
Physico‐chemical
properties
protein length:306 AA
molecular weight:34585,4 Da
isoelectric point:6,10
hydropathy:-0,61
Representative Protein Details
Accession
7d3iJ
Protein name
7d3iJ
Sequence length
461 AA
Molecular weight
50545,99000 Da
Isoelectric point
6,28067
Sequence
MAPRYWPLARGHIITSGYGPRWGTWHRGVDFGWPGGSAGQPVYAVQAGTVVSVGWDPSPGGFGHYLDIDSDDSQGANLWVYGHIVPEVQRGQQVTAGQRIAHVNGDRSTNGGVDPHCHVEVHNRVRQPFGPGRMDPMPFLQGAAYPAEASAPTPEVPVSRVLYGIDVSNHQREFDFAAAKREGFVFATHKVTEGGGYRDPFWPRAREQMREHFAGLFGGYVFCRRGSHPEREADTLLQHLGDSSIPIQLDYEDTIGGGSLEDMWARIHAIQVRGMRVFSVYLPRWFWRDRMGSPNLAGIPALWNSHYVSGKGYASTLYETAPGTITAGWAGFHPGGPPVQILQFSETARVTGQLIDVNAFRGTITELRALFAGDTGGFLMALSDAEQRQLFEAVCKPRPSLVEPEFLGGQPPAELDSATFARTADYQAFHAARQAERAAGLVEKLTERIAQLEQRLANGGK
Other Proteins in cluster: phalp2_36852
Total (incl. this protein): 93 Avg length: 427,9 Avg pI: 5,76
Protein ID Length (AA) pI
7d3iJ 461 6,28067
1bCT5 428 9,00625
1cgqv 441 4,90619
1d7Io 463 5,33993
3bZcJ 434 5,88405
3gnGA 430 6,06321
5FBTh 475 4,97241
5inoz 439 6,63501
5tG96 448 4,55578
6Svcv 424 5,71155
73fiS 430 6,31370
75eTf 464 5,40268
76YDt 424 5,48197
7A2Bv 428 5,87632
7AeqX 410 6,62540
7AesV 408 7,02458
7AetT 410 6,59715
7AuyW 408 7,85916
7BKpu 419 5,21807
7C9F1 444 5,12838
7RbKn 432 6,11624
7XLJG 399 5,92168
7bl9Q 409 8,31940
7cAqF 422 5,87075
7cFuT 443 6,25862
7cNiu 424 6,25140
7d1J7 471 5,68131
7dJl5 430 6,18342
7dPO6 466 5,08296
7fSAg 414 6,28136
7fUTW 413 5,47981
7fY1V 413 5,76776
7hrbC 454 6,01865
7kBCL 424 5,71155
7lEpo 352 7,14281
7ocQY 431 5,00174
7oeT8 464 4,87937
7ol6v 500 6,05269
7ol7X 496 7,04783
7owIa 455 5,43110
7pHzX 413 5,35988
7pIiQ 413 5,45725
7pOcD 419 5,77924
7pP1h 427 5,47049
7pP6e 413 5,61543
7pPZE 419 5,29236
7pQ6Q 422 5,27889
7pRey 422 5,16180
7pT68 413 5,45111
7pT9e 413 5,47981
7pTGL 413 5,36506
7pWJ9 413 5,25399
7pWQQ 413 5,47981
7pWho 419 5,47754
7pXj5 413 5,47981
7q49P 419 5,46754
7q5AP 413 5,35983
7q5KE 419 5,37699
7q5Un 413 5,16640
7q8y4 413 5,23882
7qado 413 5,25399
7qfnz 427 5,26900
7qfw8 413 5,70166
7qi1l 413 5,35988
7ql3s 413 5,61157
7qr3T 443 4,90079
7tMYg 431 6,34189
7tN0U 455 5,67415
7umwR 460 4,86385
7vaXg 474 5,45424
7vn6J 461 5,83995
7w0i1 470 5,50158
7w0kr 458 6,21787
7wgKs 392 5,17425
7wgLk 436 5,88411
7x2hp 467 5,66482
7xjkz 437 5,73655
7yeU3 371 5,47993
7yfzi 409 8,57889
7yyzP 424 5,80385
7zhYg 439 5,02794
8IKBB 443 5,00470
8IKBf 443 4,93700
8IKBi 443 4,90870
8IKBj 478 5,30509
8IKBn 443 4,85987
8IKBr 443 4,82690
8IKBu 367 5,01925
8Lmjc 426 6,01001
8Lovu 443 5,03789
8MCUe 426 8,39986
A0A4Y6EJJ2 306 6,27067
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10481
415Yr
 125 36,4% 417 2.408E-123
2 phalp2_24103
8hjZU
 14 47,2% 290 4.575E-112
3 phalp2_20034
1pbFu
 55 39,4% 307 5.062E-77
4 phalp2_16646
gfrU
 11 27,1% 332 1.572E-36

Domains

Domains [InterPro]
PET_M23
GH25
Unannotated
Representative sequence (used for alignment): 7d3iJ (461 AA)
Member sequence: A0A6G6XJF3 (306 AA)
1 461 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Gordonia phage Skog
[NCBI] 		2704033 Skogvirus > Skogvirus Skog
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN908687 [NCBI]
CDS location
range 2184 -> 3104
strand +
CDS
ATGACCCTGTTCGGGATCGACGTCAGCAACCACCAGAAGCAGTTCGACTTCGCGCGAGCCAAGCGCGAGGGCATGGTCTTCGCCACCCACAAGATCACCGAAGGTGACTACTACCGCGACACCTACTGGGCGCGCGCCAAGGCCGAGATGAAGCGCGAGTTCCCCGGCCTCTGGGGCGGGTACGTCTTCTGTCGGCGCGCCTCGCACCCCAAGCGCGAGGCCGAACTGCTTGCCTCGCACGCGGGCTCGACCGACTTCCCGCTGCAGATCGACTACGAGGACACCGATGGCGGCGGCAGCTACGACGACATGGTGGCCCGCTACGAGGCCTATCGTGCGGTCGGCTTCACCCAGTTCCTGCCCATCTACCTGCCGCGCTGGTTCTGGCAAGGGCGCATGGGTGCTCCCGACCTTCGTGACTTCCCTCTGCCGGTGTGGAACTCCGACTATGGCAGCAGCCGGGCGGGCAACTACAAGGCCATCTACCCCGGCGATGACAACGGGGGATGGGCGAGCTTCAAGGGGAAGCCCGTCGCACTTCTGCAGTACACCGAGCGCGGCAATGTCGCTGGACAAGCCATCGACGTCAACGCTTTTCGGGGAAGTATGCAAGACTTACAAGAACTCTTTGGAGGAGGAAAAGATATGGCTGTAGAGCACGAGATCCTGCGTCAGGAGACCGGCTCGCTGGAGGTCGGAAAGTTCCCCGGTCACAAGACCCGTCGCCATGAGGGCAGCGTGCAGGGGTCCTTCACGCAGACCGACCTCATGCGTGAGATGGACCGAGAACTCAACAGCGTCTTCAGTCTCGAAGGACGCCCGGTGGACCCCAGCAAGGGCGACACTGTGGTCGGCCACGTCCTCAGCCTGCGGGCCGAGGTCGCCGAACTCCGCAAGCTCATCGAGGAGAAGCTCAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7d3iJ) rather than this protein.
PDB ID
7d3iJ
Method AlphaFoldv2
Resolution 87.91
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50