Protein

Protein accession
A0A142F1N7 [UniProt]
Representative
VOps
Source
UniProt (cluster: phalp2_30928)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKIHDLRKQTPKRSTTRPISAITKIVRHHSATTGGDFWAFWNGRWKGSGWKTGGYHEIILRDGSVQLCYDPTMATNGVLDHNSYTYHICVVGNGQFTEAQEKTFDVRAKLAMERFGLKAGDVVGHREIPGAATECPGINMNTVRARLVGAKVETPKTEIKNETVKTSKPKSSTSPYDLIRRYFPNVSVLQRQLIAVGENLSRFRDDGVPGDETLNAIKSFQRKERLTVDGIPGPKTQARLRSKIRYVRLLRLMNPRLRGNDVRLIQRVLGVTADGIFGPITQSAVREYQRKHRLKVDGIVGPQTWSHLFG
Physico‐chemical
properties
protein length:310 AA
molecular weight:34873,6 Da
isoelectric point:10,25
hydropathy:-0,53
Representative Protein Details
Accession
VOps
Protein name
VOps
Sequence length
232 AA
Molecular weight
25426,67370 Da
Isoelectric point
9,11127
Sequence
MVIIDIRSKTPRTNGTRKETTIKKIARHHSATPTGSWEIFWPFWNKTKGWGTGGYHEIILRNGDVQLCYDPVEITNGIANHNTSTYHICVVGNGSFTDEQEKTFDERCKIAMKRFGLPAKDVLGHNEFSGTSTSCPGINMTLVRARIGSGINMVADAPTPVKKEDEELKFSSPTLKKETETSLVSKAHRQIVVSAAIKAGAHASWSEKLANGALTEADVLGLAIKYTVAVNK
Other Proteins in cluster: phalp2_30928
Total (incl. this protein): 3 Avg length: 265,3 Avg pI: 9,50
Protein ID Length (AA) pI
VOps 232 9,11127
A0AAE8XHA2 254 9,11984
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37356
8qdpv
 23 39,2% 163 2.771E-27
2 phalp2_13835
7eu8K
 10 38,3% 154 3.309E-26
3 phalp2_39380
4H4oF
 116 33,5% 161 2.142E-15
4 phalp2_28594
878Gz
 18 30,2% 162 8.973E-10
5 phalp2_20629
4LMYa
 21 31,3% 172 3.966E-09
6 phalp2_13177
2nG2h
 13 27,0% 155 1.849E-07
7 phalp2_35086
5dlBU
 33 26,8% 179 4.466E-07
8 phalp2_21323
1KDDb
 25 29,7% 175 5.989E-07
9 phalp2_29574
45kKU
 4 24,1% 199 1.115E-05
10 phalp2_23216
7DAyW
 82 21,2% 174 4.775E-05

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): VOps (232 AA)
Member sequence: A0A142F1N7 (310 AA)
1 232 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage Mgbh1
[NCBI] 		1796993 Magadivirus > Magadivirus Mgbh1
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KU665491 [NCBI]
CDS location
range 27690 -> 28622
strand +
CDS
ATGAAGATTCACGACCTACGGAAACAGACGCCTAAGCGATCAACCACGCGTCCTATTTCCGCGATCACGAAGATTGTCCGCCACCACAGCGCGACCACAGGCGGCGATTTTTGGGCGTTTTGGAACGGACGGTGGAAGGGGAGCGGTTGGAAGACGGGCGGTTATCACGAAATTATCTTACGCGACGGCTCCGTCCAATTATGTTATGACCCGACTATGGCGACAAATGGCGTGCTAGATCACAATTCGTACACGTATCATATATGCGTCGTCGGTAACGGCCAGTTTACGGAAGCACAGGAAAAGACGTTCGATGTCCGCGCTAAACTGGCGATGGAGCGCTTCGGTCTTAAAGCGGGCGACGTAGTGGGTCACCGAGAGATTCCGGGAGCCGCGACGGAATGTCCGGGAATCAACATGAATACGGTGCGGGCGCGGTTAGTAGGGGCGAAAGTGGAGACGCCTAAAACGGAAATAAAGAACGAAACAGTCAAGACGTCTAAGCCAAAGTCATCTACGTCTCCTTACGATCTAATTCGAAGATACTTCCCGAATGTTTCCGTACTACAGCGTCAGCTTATCGCAGTAGGCGAAAATCTATCTCGATTCCGAGACGACGGTGTTCCGGGCGATGAGACGCTTAACGCGATCAAGTCGTTTCAACGTAAAGAAAGGCTTACTGTAGACGGTATCCCAGGACCTAAAACGCAAGCACGGTTACGTAGTAAGATTCGATATGTAAGACTACTTCGCCTGATGAATCCGAGATTACGAGGTAATGATGTACGTCTAATTCAACGTGTACTTGGCGTTACAGCAGACGGTATCTTCGGTCCAATTACGCAATCGGCAGTCCGAGAATATCAACGTAAACACAGATTAAAGGTAGACGGAATTGTCGGACCGCAAACATGGAGTCACCTGTTTGGGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (VOps) rather than this protein.
PDB ID
VOps
Method AlphaFoldv2
Resolution 85.14
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50