Protein

Protein accession
A0A4Y5NXW3 [UniProt]
Representative
72gmg
Source
UniProt (cluster: phalp2_32215)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNPEFITVHNTYNDATANNEVAYMIRNDNQVSFHIAVDDKEAVQGIPLERNAWHCGDGGGNGNRKSIGVEICYSLSGGDRYYKAEDNAAIVVAGLMKQYNIPISKVRTHQSWSGKYCPHRMLAEGRWNSFIERVQNAYNGGGSPVMPTPIPPSNDGTKVAYINGDNVNLRKGPGTGYAVIRKLGKGECYQVWGESNGWLNLGGDQWVYNDSSYIRYTGENAPAPSKPSNDGIGVVTITADVLRVRTGPGTNYGVVKNVYQSERYQSWGYRDGWYNVGGDQWVSGEYVKFEK
Physico‐chemical
properties
protein length:291 AA
molecular weight:32199,3 Da
isoelectric point:6,96
hydropathy:-0,64
Representative Protein Details
Accession
72gmg
Protein name
72gmg
Sequence length
282 AA
Molecular weight
31609,68850 Da
Isoelectric point
9,23904
Sequence
MKYHERNVRNLNQLADNTKAAAFKWYQYCVDNGIDVLIYETIRTKEKQREYVNKGASQTMKSYHIVGQALDFVPIKSNGTEDWNGYNKEPWASAIRYAKQIGFEWGGDWKGFVDSPHLQYNYKGYGTDTFGKGAQNVPSPPPVSNDSARIAYINGNNVNLRKGPGTGYGVIRQLGKGEAYQVFAESNGWLNLGGDQWVYNDPSYIRYTGKSTPVTPQPSNDGVGVVTITADVLRVRTGPGTNYGIVKNVYQGEKYQSFGNKNGWYNVGGNQWVSGEYVNFKK
Other Proteins in cluster: phalp2_32215
Total (incl. this protein): 11 Avg length: 266,1 Avg pI: 7,84
Protein ID Length (AA) pI
72gmg 282 9,23904
4MHyD 213 9,40344
78iqY 283 4,81053
7KBNL 279 8,99497
7ouZR 281 7,56387
7rkg4 275 8,79782
7rpPy 279 8,86423
8IE7S 213 6,10840
e6uU 221 8,92354
A0A9E7PJ93 310 6,53480
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1844
3xTtn
 8 25,6% 242 1.280E-15
2 phalp2_33303
6crLy
 183 25,2% 214 3.076E-10

Domains

Domains [InterPro]
PET_M15
SH3_3
SH3_3
Representative sequence (used for alignment): 72gmg (282 AA)
Member sequence: A0A4Y5NXW3 (291 AA)
1 282 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08239, PF13539

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BthS-TP21T
[NCBI] 		2582416 Waukeshavirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK843319 [NCBI]
CDS location
range 20003 -> 20878
strand +
CDS
ATGAATCCAGAATTCATTACTGTCCACAATACTTATAACGATGCTACAGCAAATAACGAAGTGGCTTATATGATTCGTAATGATAACCAAGTATCGTTTCATATTGCGGTAGACGATAAAGAAGCTGTACAAGGTATTCCTTTAGAGCGTAACGCTTGGCATTGCGGTGATGGTGGCGGTAACGGAAATCGTAAATCTATTGGAGTTGAAATCTGTTACTCTCTAAGTGGTGGAGATCGATATTATAAAGCGGAGGATAATGCAGCTATCGTCGTAGCTGGGCTCATGAAACAGTACAATATTCCAATTAGTAAAGTTCGCACACATCAATCATGGAGTGGAAAGTATTGTCCTCATCGTATGTTAGCAGAAGGACGTTGGAATAGTTTTATTGAAAGAGTCCAAAATGCATATAACGGTGGAGGTAGTCCAGTAATGCCAACTCCTATTCCACCTTCAAACGATGGTACAAAAGTTGCTTACATTAATGGCGATAACGTGAATTTACGAAAAGGACCTGGAACTGGATATGCAGTTATTCGTAAGTTAGGTAAAGGAGAATGCTACCAAGTATGGGGTGAGTCAAATGGTTGGCTAAACTTGGGTGGCGATCAGTGGGTATATAATGATTCATCATATATTCGTTATACAGGAGAAAATGCACCAGCTCCTTCTAAACCTTCAAATGATGGCATTGGTGTAGTAACTATTACAGCTGATGTATTACGTGTTCGTACTGGTCCAGGAACTAACTATGGTGTCGTAAAAAATGTGTACCAAAGTGAAAGATATCAATCTTGGGGATATAGAGACGGTTGGTATAATGTTGGCGGCGACCAATGGGTTTCTGGTGAATATGTGAAGTTTGAAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0030420 establishment of competence for transformation biological process None (UniProt)
GO:0030435 sporulation resulting in formation of a cellular spore biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (72gmg) rather than this protein.
PDB ID
72gmg
Method AlphaFoldv2
Resolution 83.61
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50