Protein

Protein accession
A0A4D6BCB3 [UniProt]
Representative
7j23J
Source
UniProt (cluster: phalp2_26068)
Protein name
Cell wall hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSFLSKIKDGCLASWENGILPSVSAAQAILESGWGESLLAQYPNHNLFSIKVSPDWKGKRVVIPTQEYVDGKFITVAATFRKYDSWEESIKDHALFFSENDWRQFHYQNVIGEEDYKIACLALQAAGYATDPNYGAKLISLIERNHLNTWDEGILSHKGEKTMGKHLIICGHGQGQTGYDPGATNPGLGITEVGKVREFASLMKRYSGNQIDYITEQNVYDYRSLGSIGKGYETITELHFNAFNGQAKGAEVLIYAGYNPDELDQKLLSILARRFTNRGFKKVDWLYNANVAANRGYNYRLVEIAFIDNNSDMATYEANKEGMAREFVQAITGQVQSVSPSTNTPQSGAISYHVGDSVVVQKHATHYQTGQGISSWVKGKTFKIIRVKDVYQSSSKKAYLLEGINSWVLEQRCNWVNKRT
Physico‐chemical
properties
protein length:420 AA
molecular weight:47112,4 Da
isoelectric point:7,67
hydropathy:-0,43
Representative Protein Details
Accession
7j23J
Protein name
7j23J
Sequence length
302 AA
Molecular weight
33511,29060 Da
Isoelectric point
9,49021
Sequence
MGKHLVICGHGQGRSGYDPGAVNRQLDITEAGKVREFANLMKQYSGSNIDYVTDQNVYDYQSLASIGKGYDSITELHFNAFNGQARGTEILIYSGYNPDSLDQKLLGVLSKRFTNRGFKKVNWLYNANVAASRGYNYRLVEIAFIDNNSDMAIYEQHKVAMAQEFVHAITGQTQAPAVTPSRPSHLNVGDSVVVQAHATHYQTGQAISKWVKGKTYQILQVKSVNQSNSRYAYLLGGIKSWVLEQDVKATTKGHSERTYTVQKGDTLYGIAKKFNTSASNLSSKNKITNPSLIRIGQVIRLD
Other Proteins in cluster: phalp2_26068
Total (incl. this protein): 9 Avg length: 368,7 Avg pI: 9,00
Protein ID Length (AA) pI
7j23J 302 9,49021
1gOld 283 9,17258
7RneT 302 9,47655
7m2B1 306 9,29984
NsQ3 301 9,56010
A0A4D6AUP0 468 8,84430
A0A4D6AIU6 468 8,73381
A0A4D6AHN4 468 8,73381
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24803
725t1
 19 72,7% 305 1.785E-165
2 phalp2_23517
71Vqv
 51 62,8% 312 2.014E-134
3 phalp2_20638
4NMLJ
 3 27,6% 282 5.720E-22
4 phalp2_22023
5iret
 1 29,3% 225 1.897E-18
5 phalp2_38400
11B5K
 1 26,8% 332 5.757E-15
6 phalp2_24034
84xVV
 39 31,2% 208 7.732E-15

Domains

Domains [InterPro]
Ami3
Unannotated
LysM
Representative sequence (used for alignment): 7j23J (302 AA)
Member sequence: A0A4D6BCB3 (420 AA)
1 302 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan638
[NCBI] 		2548293 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK448999 [NCBI]
CDS location
range 31139 -> 32401
strand +
CDS
ATGAGTTTTTTATCAAAGATTAAAGACGGCTGTTTAGCGTCTTGGGAGAACGGCATTCTTCCGTCCGTGTCAGCAGCACAAGCTATCTTAGAGAGTGGTTGGGGTGAGTCTTTGTTAGCTCAGTACCCTAATCATAATCTCTTTAGTATTAAAGTGAGTCCTGACTGGAAAGGAAAGCGTGTTGTCATTCCAACTCAAGAATATGTGGATGGTAAGTTTATCACGGTTGCCGCCACCTTTAGAAAGTATGACTCATGGGAGGAATCTATTAAAGACCATGCGTTATTCTTTTCAGAGAATGACTGGCGTCAGTTCCACTATCAGAATGTGATTGGTGAAGAAGACTACAAAATAGCCTGTCTGGCTCTTCAAGCAGCAGGCTATGCGACTGATCCGAATTATGGAGCTAAACTCATCAGTCTTATTGAAAGAAATCATCTCAACACTTGGGATGAAGGTATTTTAAGTCATAAAGGAGAAAAAACTATGGGAAAACATCTTATCATTTGTGGGCATGGTCAGGGACAAACTGGATATGATCCTGGAGCGACGAATCCAGGACTAGGTATTACTGAAGTAGGGAAGGTACGTGAGTTTGCATCGTTGATGAAACGCTACTCTGGTAATCAGATTGATTATATTACGGAGCAAAATGTCTATGACTACCGTAGCTTAGGTAGTATCGGAAAAGGGTACGAGACCATTACAGAACTTCATTTTAATGCCTTTAATGGGCAAGCAAAAGGAGCCGAAGTACTCATTTATGCGGGTTATAATCCTGATGAGTTGGACCAGAAACTCCTTAGTATTCTTGCGCGTCGTTTTACGAATCGTGGGTTTAAGAAAGTGGACTGGCTCTATAATGCCAATGTTGCGGCAAACCGTGGGTATAACTATCGTCTCGTAGAAATAGCTTTTATCGATAACAATAGCGATATGGCAACTTATGAAGCTAATAAAGAAGGCATGGCTCGTGAGTTTGTCCAAGCGATTACTGGTCAAGTTCAATCAGTGTCTCCCAGCACCAATACTCCTCAGTCAGGGGCTATTTCCTATCACGTTGGTGATTCTGTGGTTGTTCAAAAGCATGCGACACATTATCAAACAGGACAAGGAATCTCATCTTGGGTGAAAGGCAAGACTTTCAAAATCATTCGTGTGAAAGATGTTTACCAATCTAGCAGCAAAAAAGCGTACCTTCTTGAAGGTATTAATTCCTGGGTCTTGGAGCAAAGATGTAACTGGGTCAACAAACGGACATAG

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000225ca22_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7j23J) rather than this protein.
PDB ID
7j23J
Method AlphaFoldv2
Resolution 90.18
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50